Adenine News and Research

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Adenine is one of the four bases in DNA that make up the letters ATGC, adenine is the "A". The others are guanine, cytosine, and thymine. Adenine always pairs with thymine.

Potential drugs to treat neurodegenerative diseases garner $3 million grant

A new four-year, $3 million grant will enable Scripps Research scientists to advance compounds that may protect neurons in diseases caused by toxic protein accumulation, including Parkinson's, ALS, Alzheimer's and Creutzfeldt-Jakob disease.

18 Sep 2018

A form of vitamin B3 shows potential to prevent acute kidney injury

Acute kidney injury, an often fatal condition without a specific treatment, affects up to 10 percent of all hospitalized adults in the United States and 30-40 percent in low-income countries.

21 Aug 2018

MGH researchers explore how genetic abnormality in Ewing sarcoma unleashes tumor growth

A Massachusetts General Hospital research team has used epigenome editing tools to investigate how the genetic abnormality that drives Ewing sarcoma - the second most common bone cancer in children and young adults - unleashes tumor growth.

2 Aug 2018

Researchers use guide RNAs to improve base editing system

Researchers have used guide RNAs to improve the adenine base editing (ABE) system, used by scientists to alter genetic codes in animal models of disease.

1 Aug 2018

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

A new Tel Aviv University study suggests there is hope of treating certain inborn congenital metabolic diseases -- a hope found in green tea and in red wine.

2 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

Researchers scale up fluorescence imaging technique to analyze larger areas

Researchers have scaled up a powerful fluorescence imaging technique used to study biological processes on the cellular level. Previously limited to samples just millimeters in area, the expanded approach can analyze samples with areas up to 4 square centimeters.

27 Jun 2018

Chemists find new way to make enzymes do a non-natural reaction

Princeton chemists have found a way to make a naturally occurring enzyme take on a new, artificial role, which has significant implications for modern chemistry, including pharmaceutical production.

22 Jun 2018

Non-invasive optical imaging detects early molecular signatures of disease

Chronic conditions including obesity, cardiovascular disease, and cancer often begin with early, subtle changes in cellular metabolism.

13 Jun 2018

Research identifies new genetic variations that could indicate higher prostate cancer risk

As the result of a six-year long research process, Fredrick R. Schumacher, PhD, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent.

12 Jun 2018

Researchers reveal role NAD+ molecule in turning on genes that make fat cells

Glucose is the energy that fuels cells, and the body likes to store glucose for later use. But too much glucose can contribute to obesity, and scientists have long wanted to understand what happens within a cell to tip the balance.

1 Jun 2018

New study puts forth most comprehensive tree of life for malaria parasites

A new study led by the American Museum of Natural History puts forth the most comprehensive tree of life for malaria parasites to date.

24 May 2018

Study reveals essential malaria parasite genes

Researchers have exploited a quirk in the genetic make-up of the deadly malaria parasite, Plasmodium falciparum, to create 38,000 mutant strains and then determine which of the organism's genes are essential to its growth and survival.

3 May 2018

New shape of DNA found in human cells

DNA double helix discovery is one of the major breakthroughs in human scientific history. Now in a new research, scientists have found that there may be another new shape in the DNA machinery within the cells of humans.

25 Apr 2018

Autofluorescence imaging evaluates cell metabolism and wound healing

Kyle Quinn, assistant professor of biomedical engineering at the University of Arkansas, has published a review highlighting recent advances in autofluorescence imaging and discussing its role in evaluating cell metabolism.

5 Apr 2018

UD researcher investigates role of new compound in fighting age-related diseases

A University of Delaware researcher is investigating a novel compound's role in combating age-related chronic diseases like mild cognitive disorder and dementia.

3 Apr 2018

Natural dietary supplement tends to improve blood pressure and arterial health

Scientists have long known that restricting calories can fend off physiological signs of aging, with studies in fruit flies, roundworms, rodents and even people showing that chronically slashing intake by about a third can reap myriad health benefits and, in some cases, extend lifespan.

29 Mar 2018

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Drug resistance is a major obstacle to effective treatment for patients with cancer and leukemia. Epigenetic modifying drugs have been proven effective for some patients with hematologic malignancies, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).

23 Mar 2018

Researchers develop technology to program DNA for delivering cancer drugs

DNA has an important job – it tells your cells which proteins to make. Now, a research team at the University of Delaware has developed technology to program strands of DNA into switches that turn proteins on and off.

19 Mar 2018

Engineers develop optical tool that can read metabolism at subcellular resolution

Metabolic changes in cells can occur at the earliest stages of disease. In most cases, knowledge of those signals is limited, since we usually detect disease only after it has done significant damage. Now, a team led by engineers at Tufts University School of Engineering has opened a window into the cell by developing an optical tool that can read metabolism at subcellular resolution, without having to perturb cells with contrast agents, or destroy them to conduct assays.

9 Mar 2018