Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

Existing drug may help decrease side effects of widely used cancer treatment

A Michigan State University researcher is part of an international team that found an existing drug may help decrease side effects of cisplatin, a widely used cancer treatment that was discovered at MSU in 1965.

30 Nov 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

New chemical probe can selectively inhibit human COQ8A protein in cells

Inhibition of the COQ8 protein could be beneficial in the treatment of diseases such as cancer. COQ8 is needed for the biosynthesis of coenzyme Q, also known as ubiquinone.

28 Nov 2022

Severe COVID-19 associated with an imbalance in key immune system signaling pathway

Researchers at the University of São Paulo in Brazil have found that severe COVID-19 is associated with an imbalance in an important immune system signaling pathway.

23 Nov 2022

Researchers make an incredible discovery about mammalian brains

In a new breakthrough to understand more about the mammalian brain, University of Copenhagen researchers have made an incredible discovery.

23 Nov 2022

Study reveals novel therapeutic targets for airway relaxation

Bronchial constriction is what makes many lung diseases like asthma so dangerous. Researchers have discovered a new signaling pathway that causes the airways to widen.

17 Nov 2022

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Researchers characterized the expression of IFN-1 and IFN-2, ISGs, and NF-κB in the upper respiratory tracts of patients with mild and severe COVID-19, to understand innate immune responses to SARS-CoV-2 infections.

17 Nov 2022

New drug could be a game changer for cancer patients undergoing chemotherapy

Cisplatin is a chemotherapy indicated to fight tumors in many types of cancer. However, it does have major side effects – especially kidney toxicity, that can lead to acute kidney failure.

15 Nov 2022

OHSU discovery could suggest new avenues to treat symptoms of Parkinson's disease

Researchers at Oregon Health & Science University have discovered that the neurotransmitter adenosine effectively acts as a brake to dopamine, another well-known neurotransmitter involved in motor control.

9 Nov 2022

Researchers decipher key mechanism in the pathogenesis of juvenile Parkinson's

Parkinson's disease affects 3% of population over 65 years old, and the average age of onset is 60. Regarding juvenile Parkinson, which represents the of all Parkison's cases, the disease begins before 40 years old.

8 Nov 2022

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

In a new study, researchers pursued direct-acting severe acute respiratory syndrome coronavirus-2 drugs that compete for nucleotide-binding pockets (NBPs) of SARS-CoV-2 proteins.

11 Oct 2022

Adenosine News and Research

Further Reading

Existing drug may help decrease side effects of widely used cancer treatment

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

New chemical probe can selectively inhibit human COQ8A protein in cells

Severe COVID-19 associated with an imbalance in key immune system signaling pathway

Researchers make an incredible discovery about mammalian brains

Study reveals novel therapeutic targets for airway relaxation

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

New drug could be a game changer for cancer patients undergoing chemotherapy

OHSU discovery could suggest new avenues to treat symptoms of Parkinson's disease

Researchers decipher key mechanism in the pathogenesis of juvenile Parkinson's

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Advanced type of nanoparticle could help fight hard-to-treat cancers

Dangers of recreational/medical cannabis use

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Does skin inflammation exacerbate COVID-19?

What is the impact of COVID-19 and organophosphates on cardiac health?

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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