Adipose News and Research

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GE Healthcare receives FDA 510k clearance for CoreScan to treat obesity-related disease

GE Healthcare today announced 510k clearance of CoreScan - a widely-accessible application dedicated to quickly and accurately quantifying visceral adipose tissue, or visceral "belly" fat, during body composition analysis.

26 May 2011

Key U.S. patents increase commercial rights and clinical indications

Australian regenerative medicine company, Mesoblast Limited (ASX:MSB; OTC ADR: MBLTY), today announced that the company’s product development strategy has been significantly strengthened by novel composition of matter claims granted by the United States Patent and Trade Mark Office (USPTO) in two distinct patent families to which Mesoblast has exclusive worldwide commercial rights.

23 May 2011

Cytori Therapeutics announces independent clinical study results in breast reconstruction presented at the Association of Breast Surgery conference

Cytori Therapeutics, Inc. (NASDAQ: CYTX) reports that surgeons from North Tees and Hartlepool NHS Foundation Trust have presented clinical outcomes using Adipose-Derived Regenerative Cell (ADRC) fat grafting in reconstructive breast surgery at the Association of Breast Surgery Conference in Manchester, UK, May 16-17, 2011. The procedure, referred to by Cytori as RESTORE, was separately investigated in Cytori’s own RESTORE 2 trial.

17 May 2011

Scientists decipher how hair stem cells can communicate with each other

In one of the first studies to look at the population behavior of a large pool of stem cells in thousands of hair follicles - as opposed to the stem cell of a single hair follicle - Keck School of Medicine of USC scientists deciphered how hair stem cells in mice and rabbits can communicate with each other and encourage mutually coordinated regeneration, according to an article published in the April 29 edition of the journal Science.

10 May 2011

Breakthrough research offers hope for new obesity treatment

By knocking down the expression of a protein in rat brains known to stimulate eating, Johns Hopkins researchers say they not only reduced the animals' calorie intake and weight, but also transformed their fat into a type that burns off more energy. The finding could lead to better obesity treatments for humans, the scientists report.

4 May 2011

Fat stem cells may help develop new regenerative therapies for cardiovascular disease

Stem cells extracted from body fat may pave the way for the development of new regenerative therapies including soft tissue reconstruction following tumor removal or breast mastectomy surgery, the development of tissue-engineered cartilage or bone, and the treatment of cardiovascular disease.

4 May 2011

Study examines racial differences between obesity and vitamin D among children

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that while black and white children with vitamin D deficiency both had higher fat levels, black children were more likely to have higher levels of fat just under their skin and white children were more likely to have higher levels of fat between their internal organs.

28 Apr 2011

Blueberries may help fight obesity

Recently a study out of the Texas Women's University looked at whether blueberries with their high polyphenol content could help in fighting obesity. Blueberries after all have already been cited as having positive health effects on other conditions like cardiovascular disease and metabolic syndrome. The study was conducted in Petri dishes (not live animals) using a blueberry polyphenol extract and tissue cultures from mice.

27 Apr 2011

New book on aging

Aging is a natural part of life. From the minute we are born we are heading in one certain direction: towards death. That said, it is possible to arrive at that ultimate destination graceful and vital to our last days rather than chronically ill suffering from one or many debilitating illnesses.

25 Apr 2011

Tissue Genesis commences PVD clinical trials with adipose-derived adult stem cell-coated vascular grafts

Tissue Genesis, Inc., an emerging leader in adult stem cell and regenerative medicine, announced today that it has begun clinical trials for peripheral vascular disease (PVD) with adipose (fat) derived adult stem cell-coated vascular grafts at the University of Louisville Hospital. Tissue Genesis is the first to initiate a FDA-approved trial using the patient's own adipose-derived adult stem cells (ASCs) prepared at the point-of-care.

20 Apr 2011

New research confirms high-fat diet can contribute to type 2 diabetes

A diet high in saturated fat is a key contributor to type 2 diabetes, a major health threat worldwide. Several decades ago scientists noticed that people with type 2 diabetes have overly active immune responses, leaving their bodies rife with inflammatory chemicals.

12 Apr 2011

Blueberry polyphenols can reduce obesity

The benefits of blueberry consumption have been demonstrated in several nutrition studies, more specifically the cardio-protective benefits derived from their high polyphenol content.

11 Apr 2011

Key regulator of fat cell development may provide a target for obesity and diabetes drugs

New research by scientists at The Scripps Research Institute and collaborating institutions has identified a key regulator of fat cell development that may provide a target for obesity and diabetes drugs.

8 Apr 2011

Biochemical battle of the bulge: New developments

Dozens of researchers in the coming days will lay out what's around the corner in the biochemical battle of the bulge as part of the Experimental Biology 2011 conference in Washington, D.C.

8 Apr 2011

Adipocytes associated with breast cancer could amplify 'aggressive' effect of tumors in obese patients

Apart from its direct effect on health (such as cardiovascular diseases and diabetes), obesity is increasingly suspected of playing a role in the prognosis of breast cancer and, in particular, its propensity to spread. However, no direct cause and effect relationship had been demonstrated until now. This breakthrough has finally been made through the collaborative work of two teams of researchers from Inserm, CNRS and the Université Paul Sabatier.

6 Apr 2011

Specific plant oil may reduce belly fat in humans

Scientists have known for years that belly fat leads to serious medical problems, including diabetes, cardiovascular disease, hypertension and stroke. Now, a University of Missouri researcher has found a plant oil that may be able to reduce belly fat in humans.

24 Mar 2011

CDI announces publication of footprint-free iPSCs production method in PLoS ONE journal

Cellular Dynamics International, the world's largest producer of human tissue cells for drug discovery and safety testing, today announced the publication of research demonstrating an efficient and scalable method of creating DNA integration-free, or footprint-free, induced pluripotent stem cells under a feeder-free condition using chemically defined media.

5 Mar 2011

Study confirms risk of triple-negative breast cancer among obese, physically inactive women

New findings published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, confirm the risk of breast cancer among women who are obese and not physically active, and suggests additional mechanisms beyond estrogen.

1 Mar 2011

Scientists fuse human fat stem cells with rat cardiomyocytes to form new muscles

If Dr. Doolittle is famous for talking to animals, then here's a story that might make him hold his tongue: According to new research published online in The FASEB Journal, scientists have successfully fused human stem cells derived from subcutaneous adipose tissue with muscle cells from rat hearts.