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Collaborative grant program boosts health research across Tennessee

Researchers from the University of Tennessee Health Science Center College of Medicine-Knoxville; the University of Tennessee, Knoxville; and the University of Tennessee Health Science Center Office of Research understand the challenges affecting the health and wellness of Tennesseans.

19 Jul 2024

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Blocking IL-11 signaling extends lifespan and healthspan in mice, reducing age-related metabolic decline, frailty, and cancer incidence.

18 Jul 2024

Accurate adiposity measurements key to tackling obesity-related diseases, study finds

Accurate adiposity assessment is critical for understanding obesity-related disease risks, but current clinical measurement methods have significant limitations.

16 Jul 2024

Common therapies contain different cell types, study finds

Researchers from University of California San Diego have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain completely different types of cells. The results challenge the current "one-cell-cures-all" paradigm in orthopedic stem cell therapeutics and highlight the need for more informed and rigorous characterization of injectable stem cell therapies before they are marketed for use in patients.

13 Jul 2024

Kobe University unveils key protein variants in exercise and weight loss

Some people lose weight slower than others after workouts, and a Kobe University research team found a reason.

11 Jul 2024

Researchers receive $2 million in grants to advance studies on age-related cognitive impairment

Two University of Oklahoma researchers have been awarded more than $2 million in grants from the Hevolution Foundation to further their studies on age-related cognitive impairment, with an emphasis on improving "health span," or the number of years a person remains healthy.

9 Jul 2024

Beyond BMI: New framework for obesity diagnosis prioritizes overall health

The system for diagnosing and managing obesity can no longer be about just body mass index (BMI), which is excluding many people who would benefit from obesity treatment.

8 Jul 2024

Heparan-sulfate proteoglycans found to influence Alzheimer's cell pathology

The impact of heparan-sulfate-modified proteoglycans (HSPGs) on Alzheimer's disease-associated pathways.

5 Jul 2024

Scientists unveil KLF15 transcription factor's role in white fat cells, opening new paths for obesity therapy

Researchers found that KLF15 is crucial for maintaining white adipocyte properties in subcutaneous fat, and its deletion induces beige adipocyte characteristics, suggesting new obesity treatment pathways.

4 Jul 2024

White blood cell type identified as important contributor to inflammation in obesity

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

3 Jul 2024

From Africa to Eurasia: Genetic insights into human migration and cold adaptation

"Who are we and where do we come from?" This quintessential question has intrigued humanity for millennia.

2 Jul 2024

Study shows the potential of heat treatments to promote healthier aging

New research performed with mice suggests that daily time in a warm environment such as a sauna might help older adults, especially women, combat age-related obesity and insulin resistance.

1 Jul 2024

Regulatory T cells exist as large, mobile population that travels through body to repair damaged tissue

Researchers investigated populations of regulatory T cells, a type of white blood cell, in various tissues.

1 Jul 2024

New study links psoriasis severity to skin microbiome dysbiosis

A multi-omics analysis of host-microbe interactions in psoriasis.

28 Jun 2024

Rapeseed diacylglycerol oil may combat obesity by enhancing lipid metabolism

A study in "Nutrients" explores how rapeseed diacylglycerol oil (RDG) affects fat accumulation and metabolism in obese mice, showing significant benefits in reducing obesity-related indices and improving lipid metabolism.

26 Jun 2024

High-fat diet triggers anxiety in male rats through gut-brain axis disruption

Researchers investigate the impact of a high-fat diet on gut microbiome diversity and its effects on anxiety-related symptoms.

20 Jun 2024

New insights into the role of adipokines in atrial fibrillation pathogenesis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Atrial fibrillation (AF) is a prevalent cardiac arrhythmia characterized by irregular and frequently rapid electrical activity in the atria.

14 Jun 2024

Antioxidants combat high-fat diet-induced female reproductive issues, study reveals

Researchers in Italy review how antioxidants from biological matrices can protect against reproductive issues caused by high-fat diets in women.

11 Jun 2024

Evening exercise most effective in reducing blood sugar levels for overweight and obese adults

New research reveals that moderate to vigorous physical activity in the evening for sedentary adults with overweight and obesity is most beneficial in lowering daily blood sugar levels, according to a study published in Obesity, The Obesity Society's (TOS) flagship journal.

10 Jun 2024

Research reveals light's impact on metabolism beyond circadian rhythms

A recent Nature Metabolism review highlights how light exposure or deprivation affects metabolic activities like thermogenesis and glucose homeostasis through non-circadian pathways.

4 Jun 2024