Age Related Macular Degeneration News and Research

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Experimental gene therapy proven safe for preserving vision of people with AMD

In a small and preliminary clinical trial, Johns Hopkins researchers and their collaborators have shown that an experimental gene therapy that uses viruses to introduce a therapeutic gene into the eye is safe and that it may be effective in preserving the vision of people with wet age-related macular degeneration.

17 May 2017

Age-related macular degeneration could be arrested by switching to low-glycemic diet, study finds

A study in mice finds that development of age-related macular degeneration (AMD) could be arrested by switching from a high-glycemic diet (starches as are found in white bread) to a low-glycemic (starches found in whole grains).

16 May 2017

New type of eye drop could potentially revolutionize treatment of AMD

Scientists at the University of Birmingham have developed a type of eye drop which could potentially revolutionize the treatment of one of the leading causes of blindness in the UK.

15 May 2017

Machine learning algorithm can help predict progression of age-related macular degeneration

Scientists have demonstrated that a machine learning algorithm, using images of patients' retinas obtained over time, can predict the critical moment when early or intermediate age-related macular degeneration (AMD) will progress into severe AMD.

8 May 2017

Research reveals 9.8 million Brits risk losing their sight after shunning eye tests

The Vision of Britain report, commissioned by Optegra Eye Health Care, shows an alarming percentage of Britain’s eye problems are left too late to treat, leaving 9.8 million of us living in fear of losing our sight.

3 May 2017

ARVO 2017 to showcase latest advances in treatments for eye disease and blindness

The Annual Meeting of the Association for Research in Vision and Ophthalmology is the largest gathering of eye and vision researchers in the world, with over 11,000 attendees from more than 75 countries.

2 May 2017

Healthy Vision Month: NEI focuses on women’s eye health

May is Healthy Vision Month when the National Eye Institute encourages everyone to make eye health a priority. This message is especially important for women, who make up two-thirds of all people living with blindness or visual impairment from diseases such as age-related macular degeneration, glaucoma, and cataract.

29 Apr 2017

Study finds underdiagnoses of age-related macular degeneration in primary eye care

Approximately 25 percent of eyes deemed to be normal based on dilated eye examination by a primary eye care ophthalmologist or optometrist had macular characteristics that indicated age-related macular degeneration, according to a study published by JAMA Ophthalmology.

28 Apr 2017

Scientists discover novel therapeutic target for retinal neovascularization

A team led by Massachusetts Eye and Ear researchers has identified a novel therapeutic target for retinal neovascularization, or abnormal blood vessel growth in the retina, a hallmark of advanced diabetic eye disease (proliferative diabetic retinopathy).

11 Apr 2017

JAX professor receives grant from National Eye Institute to study diseases of retinal pigment epithelium

The National Eye Institute has awarded Jackson Laboratory Professor Patsy Nishina, Ph.D., and Associate Professor Gregory Carter, Ph.D., a four-year grant totaling $2,414,304 to study diseases of the retinal pigment epithelium (RPE), with the goal of identifying druggable targets for age-related macular degeneration and other heritable retinal diseases.

11 Apr 2017

Careful counselling from clinicians may help alleviate anxiety in wAMD patients

Highly effective current treatments for vision loss need to be allied with careful counselling to ensure patients maintain good psychological health as well as good vision, new research recommends.

From The University of Manchester 11 Apr 2017

Proteomics unravels molecular mechanisms influenced by genetic variations

How does type 2 diabetes develop? A team of researchers headed by the Helmholtz Zentrum München and the Technical University of Munich has come closer to finding an answer to this problem. The team examined the functional effects of exemplary genetic variations relevant for type 2 diabetes. Their approach can be applied to many clinical pictures.

28 Mar 2017

New research identifies signal that appears to trigger retinal regeneration in zebrafish

If you were a fish and your retina was damaged, it could repair itself and your vision would be restored in a few weeks.

10 Mar 2017

In-home occupational therapy reduces depression symptoms in patients with impaired vision

Johns Hopkins researchers report that in-home occupational therapy appears to reduce the rate and severity of depression in people at higher risk for the disorder because of seriously impaired vision.

8 Mar 2017

TSRI scientists discover how key protein establishes proper vision

Scientists from the Florida campus of The Scripps Research Institute have discovered how a protein called α2δ4 establishes proper vision.

6 Mar 2017

Study finds useful way to evaluate impact of stress in AMD

Age-related macular degeneration, the leading cause of vision loss among older adults in the United States, is often associated with psychological stress.

3 Mar 2017

Scientists engineer smallest CRISPR-Cas9 system to date

Scientists at the Center for Genome Engineering, within the Institute for Basic Science0, in collaboration with KIM Eunji and KIM Jeong Hun have engineered the smallest CRISPR-Cas9 to date, delivered it to the muscle cells and in the eyes of mice via adeno-associated viruses and used it to modify a gene causing blindness.

21 Feb 2017

New RNAi treatment safely blocks ocular inflammation in mice

Scientists have developed a new RNA interference therapeutic agent that safely blocked ocular inflammation in mice, potentially making it a new treatment for human uveitis and diabetic retinopathy.

14 Feb 2017

Wills Eye expert discusses what patients need to know about Age-Related Macular Degeneration

Carl D. Regillo, MD Chief of the Wills Eye Hospital Retina Service discusses what patients need to know about Age-Related Macular Degeneration.

8 Feb 2017

Study suggests that iPSCs do not develop more mutations than subcloned cells

It's been more than 10 years since Japanese researchers Shinya Yamanaka, M.D., Ph.D., and his graduate student Kazutoshi Takahashi, Ph.D., developed the breakthrough technique to return any adult cell to its earliest stage of development (a pluripotent stem cell) and change it into different types of cells in the body.