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Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Researchers at the University of Michigan Rogel Cancer Center have identified a novel treatment approach to an aggressive type of pediatric brain cancer, using therapies already approved to treat cancer.

16 Nov 2022

Do SSRIs lower the risk of long COVID?

Researchers conducted a retrospective study to determine whether SSRIs with immunomodulatory and antiplatelet properties can decrease the risk of post-acute sequelae of COVID-19 (PASC).

15 Nov 2022

Delay in consciousness in severe cases of COVID-19 may be caused by neural hibernation

An article published in the journal PNAS provides a conceptual analysis to interpret the brain state of coronavirus disease 2019 (COVID-19) patients experiencing prolonged recovery of consciousness.

10 Nov 2022

Environmental toxicants contribute to obesity and metabolic disease

In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders.

4 Nov 2022

Fermented dairy products can improve gut mucosal immunity

In a recent study published in the journal Immunology Letters, researchers assessed the role of fermented dairy products and dairy starters in modulating gut mucosal immunity.

3 Nov 2022

Piceatannol and mTOR inhibitor combination proves be an attractive therapeutic strategy for gastric cancer

This study is led by Dr. Longtao Huangfu, and Dr. Xiaoyang Wang (Peking University Cancer Hospital & Institute). A diet of fresh fruits and vegetables may reduce the prevalence of cancers, including GC (Eusebi et al., 2020; Liu et al., 2021).

28 Oct 2022

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

A new study confirmed that the SARS-CoV-2 spike protein does not bind to human AChR’s orthosteric sites, nor does it compete with ACh, choline, or nicotine.

28 Oct 2022

Advanced type of nanoparticle could help fight hard-to-treat cancers

Nanoparticles, or tiny molecules that can deliver a payload of drug treatments and other agents, show great promise for treating cancers.

27 Oct 2022

Dangers of recreational/medical cannabis use

Researchers describe the wide range of neurological effects associated with cannabis use.

26 Oct 2022

Combination treatment improves progression-free survival in patients with oligometastatic prostate cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to intermittent hormone therapy improved progression-free survival (PFS) in patients with oligometastatic prostate cancer.

25 Oct 2022

Vast majority of people with gender dysphoria continue using gender-affirming hormone treatment

Among individuals treated at a gender identity clinic in The Netherlands, those who used puberty supressing treatment before the age of 18 and then started gender-affirming hormones, 98% (704 out of 720) continued use at follow-up, according to an observational study published in The Lancet Child & Adolescent Health journal.

20 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Study explores the effect of COVID-19 on platelet function

A new study posted in the pre-print server bioRxiv* aimed to analyze the impact of COVID-19 on platelet proteome and relate the functional responses of platelets and the formation of platelet-neutrophil aggregate in hospitalized COVID-19 patients.

17 Oct 2022

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

A new study aimed to analyze the immunometalobism BALF cells from mild to severe COVID-19 patients using computational algorithms that quantified metabolic fluxes and metabolic pathways.

13 Oct 2022

Spike-specific memory B cells develop resilience to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers explored the cross-reactivity, avidity, and kinetics of memory B-cells and serum antibodies in vaccinated and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals.

4 Oct 2022

Agonist News and Research

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Do SSRIs lower the risk of long COVID?

Delay in consciousness in severe cases of COVID-19 may be caused by neural hibernation

Environmental toxicants contribute to obesity and metabolic disease

Fermented dairy products can improve gut mucosal immunity

Piceatannol and mTOR inhibitor combination proves be an attractive therapeutic strategy for gastric cancer

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

Advanced type of nanoparticle could help fight hard-to-treat cancers

Dangers of recreational/medical cannabis use

Combination treatment improves progression-free survival in patients with oligometastatic prostate cancer

Vast majority of people with gender dysphoria continue using gender-affirming hormone treatment

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Study explores the effect of COVID-19 on platelet function

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

Spike-specific memory B cells develop resilience to SARS-CoV-2

New capsule tunnels through mucus in the GI tract to deliver large protein drugs

Study reveals key role of AKG/OXGR1 signaling pathway in maintaining male reproduction

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Potential HIV vaccine component leads to strong protection in primates

New substance boosts the effect of protein-based COVID-19 vaccines

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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