Albumin News and Research

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Sudden cardiac death number one risk for patients on dialysis

In a 10-year study of more than a thousand kidney failure patients, sudden cardiac death emerged as the number one cause of death for patients on dialysis, according to a Johns Hopkins researcher. The study, already published online and appearing in the Nov. 2 issue of Kidney International, identified systemic inflammatory response and malnutrition as key risk factors for the fatal heart attacks.

22 Oct 2008

Dual-mode nanoparticles image tumors using MRI and PET

Medical imaging represents one of the most used and useful procedures in the oncologist's diagnostic toolkit, even though each of the most useful techniques-magnetic resonance imaging (MRI), computerized tomography x-ray imaging (CT), and positron emission tomography (PET) scanning-has its own set of limitations.

17 Aug 2008

High levels of urinary albumin excretion predict hypertension

Healthy individuals with higher levels of albumin excretion, even levels considered normal, are at increased risk of developing hypertension (high blood pressure), according to a study appearing in the October 2008 issue of the Journal of the American Society Nephrology (JASN).

25 Jun 2008

Discovery of new biomarkers for growth hormone - potential for detecting growth hormone abuse

Researchers have found potential new biomarkers for growth hormone, which they say could help the sports community in detecting growth hormone abuse. The results of the animal study will be presented at The Endocrine Society's 90th Annual Meeting in San Francisco.

17 Jun 2008

Scientists identify proteins in mice that might act as biomarkers for growth hormone

Ohio University scientists have identified several proteins in mice that might act as biomarkers for growth hormone. The research could be the first step to finding a more reliable way to detect recombinant human growth hormone (rhGH), which some athletes and teenagers use illegally to boost muscle and reduce fat.

17 Jun 2008

Collaborative effort by FDA and EMEA expected to yield additional safety data when assessing new drugs

In the first use of a framework allowing submission of a single application to the two agencies, the Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) worked together to allow drug companies to submit the results of seven new tests that evaluate kidney damage during animal studies of new drugs. The tests measure the levels of seven key proteins or "biomarkers" found in urine that can provide additional information about drug-induced damage to kidney cells, also known as renal toxicity.

15 Jun 2008

CSL Behring study shows extended half-life recombinant VIIa leads to longer biologic activity

CSL Behring today presented results of a pre-clinical study that not only demonstrates the feasibility of genetically fusing factor VIIa to human albumin, but that this therapeutic protein with a prolonged half-life can lead to a longer biologic effect.

3 Jun 2008

Discovery of important markers of high risk of type 2 diabetes

Doctors are aware of a range of risk factors, mostly related to the patients' family history, overweight, and lifestyle, that contribute to the risk of developing type 2 diabetes.

26 Apr 2008

Fat-cell hormone linked to kidney disease

Reduced levels of a hormone produced by fat cells and linked to the development of insulin resistance may also be related to a higher risk of kidney disease, according to a study led by researchers at the University of California, San Diego School of Medicine and Thomas Jefferson University.

22 Apr 2008

Two new clinical trials show promise for basal cell carcinoma and pancreatic cancer

Clinical researchers at Scottsdale Healthcare and TGen have announced the results of two clinical trials that show promise for patients battling cancer.

16 Apr 2008

Uric acid in the blood may be an early sign of diabetic kidney disease

For patients with type 1 diabetes, increased levels of uric acid in the blood may be an early sign of diabetic kidney disease appearing before any significant change in urine albumin level, the standard screening test, reports a study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology.

19 Mar 2008

Uric acid may provide early clues to diabetic kidney disease

For patients with type 1 diabetes, increased levels of uric acid in the blood may be an early sign of diabetic kidney disease - appearing before any significant change in urine albumin level, the standard screening test, reports a study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology.

18 Mar 2008

Urine protein microalbuminuria may be present before hypertension diagnosis in at-risk adolescents

A protein that is an early indicator of kidney dysfunction in adults may predict hypertension in black adolescents, Medical College of Georgia researchers have found.

28 Feb 2008

XYNTHA approved for teatment of hemophilia A by FDA

Wyeth Pharmaceuticals, a division of Wyeth ( NYSE:WYE) , announced today that it has received approval from the U.S. Food and Drug Administration for XYNTHA(TM) (Antihemophilic Factor [Recombinant], Plasma/Albumin-Free), a recombinant factor VIII product, for patients with hemophilia A for both the control and prevention of bleeding episodes and surgical prophylaxis.

22 Feb 2008

Advanced Cell Technology demonstrates highly efficient process for the generation of high-purity hepatocytes

Advanced Cell Technology, Inc. has reported for the first time a robust and highly efficient process for the generation of high-purity hepatocytes (liver cells).

21 Feb 2008

Test for blood sugar not accurate in diabetic dialysis patients

The standard test for measuring blood sugar control in people with diabetes is not accurate in those on kidney hemodialysis, according to new research at Wake Forest University Baptist Medical Center.

21 Feb 2008

Standard test for blood sugar control not accurate in diabetic dialysis patients

21 Feb 2008

Two new studies examine non-invasive ways to determine liver fibrosis and cirrhosis

An enhanced version of the Original European Liver Fibrosis panel was found to have good diagnostic accuracy for fibrosis in patients with non-alcoholic fatty liver disease. Conversely, transient elastography was unreliable for detecting cirrhosis in patients with acute liver damage. The studies are published in the February issue of Hepatology, a journal by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The articles are also available online at Wiley Interscience.

5 Feb 2008

Breakdown of kidney's self-cleaning ability makes them more vulnerable to dysfunction and disease

The kidney actively cleans its most selective filter to keep it from clogging with blood proteins, scientists from Washington University School of Medicine in St. Louis reveal in a new study.

30 Jan 2008

Smart hydrogel particles: biomarker harvesting

The long and challenging effort to find blood-borne markers for cancer and other diseases may soon enter a new realm of success using a new nanoparticle that preferentially and rapidly removes small proteins and other molecules from blood while simultaneously protecting them from degradation.

16 Jan 2008

Albumin News and Research

Sudden cardiac death number one risk for patients on dialysis

Dual-mode nanoparticles image tumors using MRI and PET

High levels of urinary albumin excretion predict hypertension

Discovery of new biomarkers for growth hormone - potential for detecting growth hormone abuse

Scientists identify proteins in mice that might act as biomarkers for growth hormone

Collaborative effort by FDA and EMEA expected to yield additional safety data when assessing new drugs

CSL Behring study shows extended half-life recombinant VIIa leads to longer biologic activity

Discovery of important markers of high risk of type 2 diabetes

Fat-cell hormone linked to kidney disease

Two new clinical trials show promise for basal cell carcinoma and pancreatic cancer

Uric acid in the blood may be an early sign of diabetic kidney disease

Uric acid may provide early clues to diabetic kidney disease

Urine protein microalbuminuria may be present before hypertension diagnosis in at-risk adolescents

XYNTHA approved for teatment of hemophilia A by FDA

Advanced Cell Technology demonstrates highly efficient process for the generation of high-purity hepatocytes

Test for blood sugar not accurate in diabetic dialysis patients

Standard test for blood sugar control not accurate in diabetic dialysis patients

Two new studies examine non-invasive ways to determine liver fibrosis and cirrhosis

Breakdown of kidney's self-cleaning ability makes them more vulnerable to dysfunction and disease

Smart hydrogel particles: biomarker harvesting

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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