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Genetic marker predicts earlier onset of prostate cancer in Caucasian men

Fox Chase Cancer Center researchers have identified a genetic marker that is associated with an earlier onset of prostate cancer in Caucasian men who have a family history of prostate cancer. If the data are confirmed, the marker may help clinicians personalize prostate cancer screening.

17 May 2009

Family-based prevention program helps teens override a gene linked to risky behavior

A family-based prevention program designed to help adolescents avoid substance use and other risky behavior proved especially effective for a group of young teens with a genetic risk factor contributing toward such behavior, according to a new study by researchers at the University of Georgia.

15 May 2009

Advances in cystic fibrosis genetic testing

San Juan Capistrano, CA and Chantilly, VA –Three reports describing advances in cystic fibrosis genetic testing appear in the May 2009 issue of The Journal of Molecular Diagnostics .

27 Apr 2009

MicroRNA may link smoking risk gene to neurobiology of addiction

During the past several years, significant progress has been made in identifying susceptibility genes for nicotine dependence through genetic linkage and association analyses.

23 Apr 2009

Common gene variant linked to development of prostate cancer

Researchers have described how a common genetic variation may be involved in the development of prostate cancer.

22 Apr 2009

Genetic variations in inflammation pathway may predict risk of invasive bladder cancer

Genetic variations in the inflammation pathway may predict who would respond to Bacillus-Calmette-Guerin (BCG) treatment and who might experience a recurrence among patients with non-muscle invasive bladder cancer, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009.

20 Apr 2009

RNA interference can be used to silence genes selectively - potential for Huntington's disease therapy

Howard Hughes Medical Institute researchers have designed tiny RNA molecules that shut off the gene that causes Huntington's disease without damaging that gene's healthy counterpart, which maintains the health and vitality of neurons.

12 Apr 2009

Genetic risk factors play role in autoantibody-negative rheumatoid arthritis

During the past few years, several new genetic risk factors for rheumatoid arthritis (RA) have been identified.

8 Apr 2009

Helicos BioSciences releases transcriptome sequencing datasets as open access

Helicos BioSciences has announced the release of transcriptome sequencing (RNA-Seq) datasets on the HeliSphere Technology Center, the company's open access Web site for sharing Helicos datasets and bioinformatics software tools.

6 Apr 2009

Study looks at vitamin supplements for celiac disease

Coeliac disease is a typical example of a malabsorption syndrome conferring increased risk for various deficiency states, including folate and vitamin B12.

2 Apr 2009

Possible genetic cause for advanced colorectal cancer in blacks

Researchers have identified a possible genetic cause for increased risk for a more advanced form of colorectal cancer in blacks that leads to shorter survival, according to data published in Clinical Cancer Research , a journal of the American Association for Cancer Research.

1 Apr 2009

A comparative analysis of four beta blocker trials

ARCA biopharma, Inc. has announced that a comparative analysis of primary endpoint data from four beta blocker trials was presented at the American College of Cardiology 58th Annual Scientific Session being held March 29-31, 2009.

29 Mar 2009

Researchers look at genetic dynamics of inbreeding depression

Researchers have taken a first look at the broad genetic changes that accompany reproductive declines in inbred populations.

12 Mar 2009

Study looks at effect of vitamin B6, folate, and vitamin B12 supplements in coeliac disease

Coeliac disease is a typical example of a malabsorption syndrome conferring increased risk for various deficiency states, including folate and vitamin B12.

3 Mar 2009

Researchers discover gene variation linked to cocaine addiction and cocaine-induced paranoia

Researchers from Boston University School of Medicine (BUSM) and Yale University School of Medicine and the University of Connecticut School of Medicine, have discovered that variants in the á-endomannosidase (MANEA) gene are associated with cocaine addiction and cocaine-induced paranoia in European American and African American populations.

2 Mar 2009

Statistical analysis could yield new drug target for multiple sclerosis

An elaborate statistical analysis of genes from more than 7,000 individuals has identified an amino acid that appears to be a major risk factor for multiple sclerosis, a devastating autoimmune disorder that afflicts 2.5 million people worldwide.

15 Feb 2009

Researchers uncover serotonin transporter gene SLC6A4's role in severity of drinking

New research from the University of Virginia Health System could help explain why some alcoholics are more severe drinkers than others.

5 Feb 2009

Genetic variation cues social anxiety in monkeys and humans

A genetic variation involving the brain chemical serotonin has been found to shape the social behavior of rhesus macaque monkeys, which could provide researchers with a new model for studying autism, social anxiety and schizophrenia.

15 Jan 2009

Discovery of first gender-linked susceptibility gene for late-onset Alzheimer's disease

In the Jan. 11 online edition of Nature Genetics, they report the results of their two-stage genome-wide association study of patients with Alzheimer's disease. The research showed that women who inherited two copies of a variant in the PCDH11X gene, found on the X chromosome, are at considerably greater risk of developing Alzheimer's disease.

12 Jan 2009

Innovative brain-scan technology helps visualize brain aging before symptoms appear

UCLA scientists have used innovative brain-scan technology developed at UCLA, along with patient-specific information on Alzheimer's disease risk, to help diagnose brain aging, often before symptoms appear.

6 Jan 2009