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High HDL-C levels and cardiovascular risks - what you need to know!

Research paper investigates the relationship between very high levels of high-density lipoprotein cholesterol (HDL-C) and cardiovascular outcomes in the general population. The study reveals that while men with high HDL-C face an increased risk of all-cause death and cardiovascular death, this association is not observed in women without coronary artery disease.

22 May 2023

Gout unveiled as surprising culprit in neurodegenerative diseases

Research highlights the association between gout and neurodegenerative diseases, revealing that gout patients exhibit smaller brain volumes, increased brain iron markers, and a higher incidence of conditions such as dementia, Parkinson's disease, and essential tremor, particularly within the first three years after diagnosis.

22 May 2023

Newly developed method can help identify the special differences in genetic information

Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests.

22 May 2023

What are the genetic associations between modifiable risk factors and Alzheimer's disease?

Researchers assessed associations between genetic risk factors and Alzheimer's.

19 May 2023

Turn down the heat: Spicy foods linked to memory decline in inactive seniors

Research investigates the association between spicy food consumption and Alzheimer's disease (AD) or cognitive decline in older adults. The study found that a high level of spiciness in food is associated with decreased memory or global cognition, and this relationship is worsened by a physically inactive lifestyle.

18 May 2023

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

The gene ECHS1 encodes for enoyl-CoA hydratase short-chain 1, a mitochondrial enzyme involved in branched-chain amino acid and fatty acid metabolism.

18 May 2023

Is there an association between long-term plasma caffeine intake and adiposity, type 2 diabetes, and cardiovascular diseases?

Investigate the effects of long-term exposure to higher plasma caffeine concentrations on T2D, adiposity, and cardiovascular diseases.

18 May 2023

Study explores the role of dynamin protein DYN-1 in regenerative axonal fusion

A study explores the role of the dynamin protein DYN-1 in axonal fusion. The axon is a long, thin protrusion of nerve cells that carries electrical impulses.

9 May 2023

Genetics can boost and complicate dementia risk linked to air pollution exposure

Three years ago, an international study commissioned by the journal Lancet listed 12 modifiable factors that increased the risk of dementia, including three new ones: excessive alcohol, head injury and air pollution.

3 May 2023

Is there an association between hearing aid use and risk of dementia?

Researchers examined the correlation between the use of hearing aids and the risk of developing dementia.

19 Apr 2023

Blood levels of glycans can predict the risk of Alzheimer's disease

Early diagnosis and treatment of Alzheimer's disease requires reliable and cost-effective screening methods.

12 Apr 2023

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes.

11 Apr 2023

Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK

Study explores the emerging invasive group A Streptococcus M1uk lineage,

7 Apr 2023

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

Researchers explored the correlation between autoimmunity and obesity.

3 Apr 2023

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

A recent review published in Biochemical Pharmacology summarized the ongoing research, providing insights into pathophysiology and emerging drugs for Alzheimer’s disease (AD).

31 Mar 2023

Can poor diet and lifestyle behaviors modify genomic susceptibility to impulsivity?

Researchers evaluated the effects of poor diet quality and lifestyle behaviors on modifying the genomic susceptibility to impulsivity.

30 Mar 2023

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

The authors of a new study under review at the journal Scientific Reports and currently posted to the Research Square preprint* server proposed a novel analysis pipeline to help identify mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription-polymerase chain reaction (RT-PCR) primer regions.

29 Mar 2023

Despite raising LDL levels, coffee lowers systolic and diastolic blood pressure

Researchers performed a cross-sectional analysis of the general population of Hamburg City, Germany.

27 Mar 2023

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

In a recent study published in the journal PLOS Pathogens, researchers in the United States of America (USA) and Canada found molecular evidence that the parasitic hookworms (Ancylostoma caninum) in pet dogs across the USA are becoming increasingly resistant to benzimidazole, a broad-spectrum anthelmintic drug used for infection control.

22 Mar 2023

Fiber intake associated with lower risk of cognitive decline in old people with ApoE ε4 genotype

Fiber intake is associated with a lower risk of developing cognitive decline in those old people with the Apolipoprotein E ApoE ε4 genotype, regarded as a genetic risk factor linked to the development of Alzheimer's disease.

22 Mar 2023

Allele News and Research

High HDL-C levels and cardiovascular risks - what you need to know!

Gout unveiled as surprising culprit in neurodegenerative diseases

Newly developed method can help identify the special differences in genetic information

What are the genetic associations between modifiable risk factors and Alzheimer's disease?

Turn down the heat: Spicy foods linked to memory decline in inactive seniors

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

Is there an association between long-term plasma caffeine intake and adiposity, type 2 diabetes, and cardiovascular diseases?

Study explores the role of dynamin protein DYN-1 in regenerative axonal fusion

Genetics can boost and complicate dementia risk linked to air pollution exposure

Is there an association between hearing aid use and risk of dementia?

Blood levels of glycans can predict the risk of Alzheimer's disease

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

Can poor diet and lifestyle behaviors modify genomic susceptibility to impulsivity?

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

Despite raising LDL levels, coffee lowers systolic and diastolic blood pressure

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

Fiber intake associated with lower risk of cognitive decline in old people with ApoE ε4 genotype

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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