Amniotic Fluid News and Research

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Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.

9 Oct 2005

Amnioinfusion does not reduce the risk of meconium aspiration syndrome

An international randomized trial, funded by the Canadian Institutes of Health Research (CIHR), has revealed that amnioinfusion, the infusion of saline into the uterus, does not reduce the risk of meconium aspiration syndrome (MAS), as previously believed.

6 Sep 2005

Changes to prenatal genetic testing could mean more babies born with abnornalities

A study in the UK suggests that a proposed change to the type of prenatal genetic testing offered to couples in the UK, could possibly result in certain chromosome abnormalities being missed.

4 Jul 2005

Birth abnormality rates could increase if proposed changes to prenatal testing go ahead

A proposed change to the type of prenatal genetic testing offered to couples in the UK could result in certain chromosome abnormalities being missed, suggests a study published online today (Thursday June 30, 2005) by The Lancet.

1 Jul 2005

Maternal smoking during pregnancy associated with chromosomal abnormalities

A preliminary report suggests that maternal smoking during pregnancy is associated with increased chromosomal abnormalities in fetal cells, according to a study in the current issue of JAMA.

9 Mar 2005

Pregnant women who smoke risk their child getting cancer

Smoking has a wide range of possible consequences during and after pregnancy, such as infertility, coagulation problems, obstetric complications such as extrauterine pregnancy and placenta previa, and intrauterine growth retardation, according to background information in a recent study.

8 Mar 2005

Researchers can now predict who will benefit from cerclage

Doctors treating pregnant women with threatened preterm birth sometimes sew the cervix closed, a procedure known as cerclage. Despite this traditional intervention, many women still lose the pregnancy.

1 Mar 2005

New technique to identify fetal genetic material from amniotic fluid

A preliminary report suggests that cell-free fetal messenger RNA (ribonucleic acid) can be extracted from amniotic fluid (fluid around the fetus), and then be analyzed to study gene expression changes that may reflect the well-being of the fetus, according to a paper in the February 16 issue of JAMA, a theme issue on medical applications of biotechnology.

15 Feb 2005

Ingestion of afterbirth appears to promote maternal behavior in mammals

A behavioral neuroscientist at the University at Buffalo holds that the ingestion of afterbirth by a mother, a feature of pregnancy in nearly all non-human mammals, not only relieves postpartum pain, but optimizes the onset of maternal behavior by mediating the activity of specific opioid activity circuits in the brain.

13 Feb 2005

Markers for premature birth risk at the molecular level

For the first time, researchers have successfully profiled the amniotic fluid metabolome (the sum of all metabolic processes occurring in the amniotic fluid), in order to identify which women who have experienced preterm labor are also at risk for delivering a premature baby.

10 Feb 2005

Turning point in the history of preterm labor diagnosis

A combination of four proteins that result from inflammation and infection and lead to premature birth can be rapidly and accurately detected in the amniotic fluid of pregnant women using proteomics technology, Yale researchers report in two studies in the February issue of British Journal of Obstetrics and Gynecology.

7 Feb 2005

Suctioning babies to prevent a potentially fatal respiratory disease is probably ineffective

The widely practised procedure of suctioning babies to prevent a potentially fatal respiratory disease is probably ineffective, conclude authors of a study in this week’s issue of THE LANCET. Suctioning is used to remove mucus from baby’s airway or breathing passages.

15 Aug 2004

Lack of a gene called LBP-1a in the embryo prevents normal growth of blood vessels in the placenta

The lack of a gene called LBP-1a in the mouse embryo prevents normal growth of blood vessels in the placenta. This finding suggests that a similar defect in humans could play a role in fetal growth retardation, infant mortality and spontaneous abortion.

6 Aug 2004

Amniotic Fluid News and Research

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

Amnioinfusion does not reduce the risk of meconium aspiration syndrome

Changes to prenatal genetic testing could mean more babies born with abnornalities

Birth abnormality rates could increase if proposed changes to prenatal testing go ahead

Maternal smoking during pregnancy associated with chromosomal abnormalities

Pregnant women who smoke risk their child getting cancer

Researchers can now predict who will benefit from cerclage

New technique to identify fetal genetic material from amniotic fluid

Ingestion of afterbirth appears to promote maternal behavior in mammals

Markers for premature birth risk at the molecular level

Turning point in the history of preterm labor diagnosis

Suctioning babies to prevent a potentially fatal respiratory disease is probably ineffective

Lack of a gene called LBP-1a in the embryo prevents normal growth of blood vessels in the placenta

New method for detecting premature birth

Link between oral bacterium and premature babies

Research suggests protein released from lungs could initiate labour

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

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