Amyotrophic Lateral Sclerosis News and Research

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Scientists decode the marker protein that can be used to ‘‘see’’ neuroinflammation

Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric diseases.

25 Sep 2023

Researchers find a promising drug candidate for the treatment of ALS

A research group at the University of Helsinki and its partners have found a promising drug candidate for the treatment of amyotrophic lateral sclerosis (ALS).

22 Sep 2023

Ongoing gene therapy trials have driven increased use of ALS genetic testing, finds study

Researchers at The Ohio State University Wexner Medical Center and College of Medicine led the creation of evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.

19 Sep 2023

Is maple syrup the ultimate natural sweetener? Researchers say it's more than just tasty!

Scientists explore the myriad benefits of maple syrup, revealing its nutritional, pharmacological, and sensory advantages over traditional sweeteners. From antioxidant and anti-inflammatory properties to controlling blood sugar and even potential anticancer effects, maple syrup is more than just a tasty topping.

14 Sep 2023

People who require specialized neurologic care most often travel long distances, study finds

Nearly one in five people on Medicare travel 50 or more miles one way to see a neurologist, a doctor who diagnoses and treats diseases of the brain and nervous system, according to research published in the September 13, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

13 Sep 2023

Unhealthy pathobiome in the brain could cause some forms of Alzheimer's and related dementias

The human microbiome includes the genetic material of more than 100 trillion tiny microorganisms – fungi, yeast, bacteria, and even viruses, most of which hang out in our gastrointestinal tract to serve as guardians of our health.

13 Sep 2023

Scientists develop new method to detect key fat-filled particles in the brain

Scientists have created a method to detect key fat-filled particles known as lipoproteins in the central nervous system, opening a new view into the workings of the brain.

12 Sep 2023

Ohio State University Wexner Medical Center administers first targeted gene therapy for ALS

The Ohio State University Wexner Medical Center is one of the first nationwide to administer a targeted gene therapy for patients with a specific form of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.

8 Sep 2023

Speech Accessibility Project needs more participants with Parkinson's

The Speech Accessibility Project is almost halfway through its first phase of gathering voice recordings from people with Parkinson's.

24 Aug 2023

Engineered adeno-associated virus vector yields high transduction of the brain vasculature

Researchers have developed an engineered adeno-associated virus (AAV) vector that yields high transduction of brain vascular pericytes and smooth muscle cells.

24 Aug 2023

Zebrafish model could help unlock Parkinson's disease mechanisms

Nearly one million people in the United States are living with Parkinson's disease, making it the second-most common neurodegenerative disease after Alzheimer's.

21 Aug 2023

A new Medicare proposal would cover training for family caregivers

Even with extensive caregiving experience, Patti LaFleur was unprepared for the crisis that hit in April 2021, when her mother, Linda LaTurner, fell out of a chair and broke her hip.

18 Aug 2023

Machine learning in neurodegenerative disease research: a growing trend

Scientists explore the utility of machine learning methods in the field of neurodegenerative disease diagnosis, prognosis, and treatment effect prediction.

4 Aug 2023

Study finds α5 integrin as a potential therapeutic target in amyotrophic lateral sclerosis

Researchers examined the therapeutic effects of targeting integrins for treating Amyotrophic lateral sclerosis (ALS).

3 Aug 2023

Research reveals surprising genetic overlap between neurological and psychiatric disorders

Researchers compared the shared genetic risk and biological foundations of neurological and mental illnesses.

1 Aug 2023

Monoclonal antibody shows promise in slowing progression of ALS

New research reveals a type of monoclonal antibody already tested in certain forms of cancer may be a promising treatment in stopping the progression of amyotrophic lateral sclerosis, or ALS, a fatal neurodegenerative disease.

31 Jul 2023

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Researchers at the Francis Crick Institute and UCL have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS).

21 Jul 2023

Study highlights the potential of cell replacement therapy for Huntington's disease

New research appearing in the journal Nature Biotechnology answers important questions about the viability of treatments that seek to replace diseased and aged cells in the central nervous system with healthy ones.

17 Jul 2023

Study suggests anxiety increases the risk of subsequent cognitive progression in non-dementia elderly

Researchers investigate the effects of anxiety on cognitive degeneration in non-dementia elderly.

14 Jul 2023

British neuroscientist wins Hartwig Piepenbrock-DZNE Prize for contributions to dementia research

This year's "Hartwig Piepenbrock-DZNE Prize", endowed with 60,000 euros, goes to the British neuroscientist Alison Goate, DPhil. The award recognizes her outstanding contributions to research into Alzheimer's disease and frontotemporal dementia.

13 Jul 2023