Androgen News and Research

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New, improved organoids shed light on untreatable form of prostate cancer

A multi-institutional team of investigators led by bioengineer Ankur Singh has developed research tools that shed new light on a virtually untreatable form of prostate cancer, opening a pathway that may lead to novel therapeutics and a glimmer of hope for patients.

24 Nov 2021

Using the contraceptive pill to reduce risk of type-2 diabetes in women with PCOS

In this interview, News-Medical speaks to Professor Weibke Arlt about her recent research into how the contraceptive pill affects type 2 diabetes in women with PCOS.

22 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

Regular blood tests can identify prostate cancer patients who are resistant to treatment

Regular blood tests before and during chemotherapy for prostate cancer can detect whether or not a patient is resistant or developing resistance to treatment with docetaxel, according to research presented at the NCRI Festival.

11 Nov 2021

Study identifies RNA molecule that suppresses prostate tumors

Many patients with prostate cancer are treated with drugs that lower or block hormones that fuel tumor growth. While the drugs are effective for a time, most patients eventually develop resistance to these therapies.

6 Nov 2021

Understanding the current medical landscape of prostate cancer

In this interview, News-Medical talks to Dr. Simon Chowdhury and Laetitia Guilloux about the current state of prostate cancer, it's prevalence, treatment options and its future.

From Janssen Pharmaceuticals 2 Nov 2021

Prostate cancer drugs could be effectively repurposed to inhibit melanoma in men

New research shows that testosterone promotes melanoma proliferation by activating a newly recognized nonclassical testosterone receptor in melanoma cells called ZIP9 (encoded by the SLC39A9 gene), a zinc transporter that is not intentionally targeted by any available therapeutics but is widely expressed in human melanoma.

27 Oct 2021

Factors contributing to a weak antibody response to the Pfizer COVID-19 vaccine

A new study discusses risk factors for the failure of seroconversion following full vaccination with the COVID-19 Pfizer vaccine.

18 Oct 2021

Contraceptive pill can reduce the risk of type 2 diabetes in women with PCOS, study reveals

A study led by the University of Birmingham has revealed for the first time that the contraceptive pill can reduce the risk of type 2 diabetes by over a quarter in women with polycystic ovary syndrome (PCOS).

15 Oct 2021

Impact of BRCA1 mRNA expression on survival of patients breast and colorectal cancer

Oncotarget published "Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients" which reported that LMNB2 is a chromatin remodeling protein that also plays a role in eukaryotic cell proliferation by organizing the nuclear membrane during mitosis.

13 Oct 2021

Common gut bacteria can fuel prostate cancer growth and treatment resistance

Common gut bacteria can fuel the growth of prostate cancers and allow them to evade the effects of treatment, a new study finds.

7 Oct 2021

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.

27 Sep 2021

Compound extracted from orchid could be a potential treatment option for prostate cancer

Research led by the Centenary Institute has found that a compound extracted from a commonly cultivated orchid could be a potential new treatment option for prostate cancer.

22 Sep 2021

Cardiovascular safety of prostate cancer treatments remains unresolved

The relative cardiovascular safety of different types of androgen deprivation therapy (ADT) for prostate cancer remains unresolved after the PRONOUNCE trial was terminated early. The late breaking research is presented in a Hot Line session today at ESC Congress 2021.

30 Aug 2021

Does SARS-CoV-2 affect male fertility?

A recently published review describes the state of current knowledge regarding the impact of SARS-CoV-2 on the male reproductive system.

23 Aug 2021

Researchers identify genes associated with biochemical recurrence in prostate adenocarcinoma

Aging-US published "Identification of microenvironment related potential biomarkers of biochemical recurrence at 3 years after prostatectomy in prostate adenocarcinoma" which reported that the authors aimed to identify the potential prognostic genes in the prostate adenocarcinoma microenvironment and to estimate the causal effects simultaneously.

20 Aug 2021

UH researcher set to explore how testosterone works in the brain

Most people have some idea about the hormone testosterone –how it regulates male behavior or how too little of it might cause a decrease in libido and too much might cause aggressive and irritable behavior. Turns out, no one yet knows how testosterone really does all that.

16 Aug 2021

Genomic test may help identify prostate cancer patients at high risk of disease progression

After a biopsy comes back positive for prostate cancer, patients and their doctors are often left with a choice between taking a watch-and-wait approach, known as active surveillance, or proceeding with surgery or radiation.

27 Jul 2021

Anti-androgen therapy for patients with advanced prostate cancer may fuel bone metastasis

Dr Bock, under the mentorship of Distinguished Professor Dietmar Hutmacher, from QUT Centre for Biomedical Technologies, has focused her research on bone metastases from breast and prostate cancers.

7 Jul 2021

Serum testosterone status recovery an accurate predictor of survival in male COVID-19 patients

In a study available on the medRxiv* the preprint server, researchers from Spain showed that testosterone trajectories are very accurate individual predictors of survival in male patients with COVID-19. To better understand the relationship between testosterone levels and disease severity, they studied a group of male and female COVID-19 patients assessing their serum and blood biomarkers in association with outcome of disease.

6 Jul 2021