Anemia News and Research

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Anemia is a decrease in normal number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency. The three main classes of anemia include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis). Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few.

Study: Iron infusions superior to blood transfusions for surgical patients with anemia

In a rigorous medical records study covering tens of thousands of patients, Johns Hopkins Medicine researchers conclude that some patients with preoperative anemia have better outcomes if they get iron infusions before surgery rather than standard red blood cell transfusions.

25 Jul 2024

Unraveling the role of TAL1 and miR-146b-5p in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive form of leukemia that arises from the malignant transformation of T-cell progenitors.

23 Jul 2024

DDX41: A unique player in myeloid leukemogenesis

A new editorial paper was published in Oncotarget's Volume 15 on July 2, 2024, entitled, "DDX41 and its unique contribution to myeloid leukemogenesis."

19 Jul 2024

Scurvy on the rise in the United States: Pediatric cases triple in five years

Researchers found that pediatric scurvy cases tripled from 2016 to 2020, highlighting a significant rise in incidence, particularly among low-income, male, and autistic children.

19 Jul 2024

Low-GI Mediterranean diet boosts quality of life but not sleep in diabetes-prone adults

Researchers found that a low-glycemic index Mediterranean diet improves some aspects of health-related quality of life but not sleep in adults at risk for type 2 diabetes.

15 Jul 2024

Study highlights marked increase in iron deficiency among female military recruits

After five months of basic military training, the proportion of female recruits with iron deficiency had more than doubled, from 25% to 55%.

8 Jul 2024

Small molecule discovery offers hope for treatment of Angelman syndrome

Angelman syndrome is a rare genetic disorder caused by mutations in the maternally-inherited UBE3A gene and characterized by poor muscle control, limited speech, epilepsy, and intellectual disabilities.

8 Jul 2024

Decoding the significance of subnormal liver enzyme activity

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).

3 Jul 2024

Study reveals laboratory predictors of periprosthetic joint infection in morbidly obese patients

For patients with severe obesity undergoing knee or hip replacement, commonly obtained laboratory values – including markers of anemia and inflammation – are independent predictors of the risk of periprosthetic joint infection (PJI), reports a study in The Journal of Bone & Joint Surgery.

1 Jul 2024

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Researchers investigated whether stem-like T lymphocytes are involved in ulcerative colitis pathogenesis.

21 Jun 2024

Promising gene editing therapy shows hope in sickle cell disease cure

Researchers have presented the latest findings from a clinical trial aimed at discovering a cure for sickle cell disease, a painful genetic blood disorder with limited treatment options.

14 Jun 2024

Study advocates for liberal blood transfusions in TBI intensive care

Increased use of blood transfusions after major traumatic brain injury could help people hospitalized in intensive care units regain greater functional independence and a better quality of life.

13 Jun 2024

MEK inhibitor trametinib shows potential in pediatric JMML treatment

The MEK inhibitor trametinib (Mekinist) was an effective treatment for pediatric patients with relapsed or refractory juvenile myelomonocytic leukemia (JMML) enrolled in a phase II clinical trial, with seven of 10 patients alive after a median of two years.

13 Jun 2024

Stanford study finds 15-day paxlovid treatment safe but ineffective for long COVID

In a clinical trial conducted by Stanford Medicine investigators and their colleagues, a 15-day course of Paxlovid -; an antiviral drug combination targeting SARS-CoV-2, the virus that causes COVID-19 -; proved safe as an extended-duration treatment but didn't lessen select symptoms of the syndrome known as long COVID: the persistence, or reappearance, of COVID-related symptoms three months or more after an initial COVID-19 infection.

7 Jun 2024

Novel technique maps enhancer-gene interactions in single cells

The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time.

5 Jun 2024

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Clinicians at Georgetown University's Lombardi Comprehensive Cancer Center reported promising preliminary findings based on outcomes in the first six patients with metastatic pancreatic cancer enrolled in a phase 2 clinical trial of the experimental drug BXCL701 in combination with the immunotherapy drug pembrolizumab (Keytruda).

3 Jun 2024

Anemia News and Research

Further Reading

Study: Iron infusions superior to blood transfusions for surgical patients with anemia

Unraveling the role of TAL1 and miR-146b-5p in T-cell acute lymphoblastic leukemia

DDX41: A unique player in myeloid leukemogenesis

Scurvy on the rise in the United States: Pediatric cases triple in five years

Low-GI Mediterranean diet boosts quality of life but not sleep in diabetes-prone adults

Study highlights marked increase in iron deficiency among female military recruits

Small molecule discovery offers hope for treatment of Angelman syndrome

Decoding the significance of subnormal liver enzyme activity

Study reveals laboratory predictors of periprosthetic joint infection in morbidly obese patients

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Promising gene editing therapy shows hope in sickle cell disease cure

Study advocates for liberal blood transfusions in TBI intensive care

MEK inhibitor trametinib shows potential in pediatric JMML treatment

Stanford study finds 15-day paxlovid treatment safe but ineffective for long COVID

Novel technique maps enhancer-gene interactions in single cells

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Pregnant women less likely to suffer long COVID, study finds

Heavy menstrual bleeding raises heart disease risk in young women

Inherited iron defects uncovered in endemic Indian population

FDA clears Nova’s Stat Profile Prime Plus analyzer for micro capillary sample mode

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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