Anemia News and Research

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Anemia is a decrease in normal number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency. The three main classes of anemia include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis). Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few.

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Their tickets were booked. Their schedules were set. The students were finally going to test their product on real people. But in July, Sierra Leone's COVID-19 level spiked almost overnight, and Lehigh's Sickle Cell Anemia Diagnostic Device team lost yet another opportunity to conduct fieldwork.

1 Nov 2021

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

Kawasaki disease (KD) is rare, with fewer than 6,000 diagnosed cases per year in the United States. It is most common in infants and young children and causes inflammation in the walls of some blood vessels in the body.

27 Oct 2021

Gene therapy strategy against Angelman syndrome shows early promise

Scientists at the UNC School of Medicine have reported in the journal JCI Insight encouraging early tests of a gene therapy strategy against Angelman syndrome, a neurodevelopmental disorder that features poor muscle control and balance, hard-to-treat epilepsy, and intellectual disabilities.

22 Oct 2021

Red blood cells play a much larger role in the immune system than previously thought

New research has revealed that red blood cells function as critical immune sensors by binding cell-free DNA, called nucleic acid, present in the body's circulation during sepsis and COVID-19, and that this DNA-binding capability triggers their removal from circulation, driving inflammation and anemia during severe illness and playing a much larger role in the immune system than previously thought.

20 Oct 2021

Millets can play a promising role in preventing and reducing iron deficiency anemia, study shows

A new study has shown that regular consumption of millets can improve hemoglobin and serum ferritin levels to reduce iron deficiency anemia, which is rising globally.

19 Oct 2021

Better clinical outcomes in COVID-19 and vaccine-related myocarditis than classic myocarditis in children

Researchers have investigated the differences between 'classic' myocarditis, COVID-19 induced myocarditis, and vaccine-related myocarditis.

11 Oct 2021

Nearly 20% of adults have elevated troponin levels after major non-cardiac surgery

About 20% of adults who have major non-cardiac surgery had elevated troponin levels, yet nearly all of them did not have symptoms of injury, according to a new scientific statement from the American Heart Association.

4 Oct 2021

Small sachet of fortified food-based supplement could promote healthy development of children

A small sachet of a fortified food-based supplement added to young children's daily diets in low- and middle-income countries has shown remarkable results in preventing child mortality and malnutrition, while also promoting healthy development.

30 Sep 2021

Review describes nutritional imbalances in adults with celiac disease following a gluten-free diet

A review by the GLUTEN3S research group at the UPV/EHU-University of the Basque Country describes the nutritional imbalances found in adults suffering from celiac disease who follow a gluten-free diet. The keys to avoiding possible problems among these patients are proper monitoring and good nutritional education, to ensure a diet that is not only gluten-free but well-balanced also.

27 Sep 2021

Penn scientists win 2021 Lasker Award for the discovery of therapeutic mRNA technology

As mRNA-based SARS-CoV-2 vaccines are deployed to protect hundreds of millions of people across the world and point the way to end the deadly global COVID-19 pandemic, the University of Pennsylvania scientists whose prescient discovery science effort laid the foundation for swift vaccine development have been awarded the 2021 Lasker~DeBakey Clinical Medical Research Award.

24 Sep 2021

Potential covalent SARS-CoV-2 spike protein inhibitors

There remains a significant need for new and effective drugs that can be used to treat COVID-19.

23 Sep 2021

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients

Heart abnormalities are common complications of sickle cell anemia (SCA) that can contribute to severe disease symptoms and even death.

16 Sep 2021

Combination of chemotherapy and immune checkpoint inhibitors shows promise in NSCLC patients with untreated brain metastases

Treatment with atezolizumab plus carboplatin and pemetrexed was safe and yielded promising brain progression-free survival in patients with nonsquamous non-small cell lung cancer with untreated and asymptomatic brain metastases.

12 Sep 2021

Physical exercise can improve cancer-induced anemia

Many cancer patients suffer from anemia leaving them fatigued, weak, and an impaired ability to perform physical activity.

9 Sep 2021

People living with HIV have higher risk of sudden cardiac death, finds study

People living with human immunodeficiency virus (HIV) have a higher risk of sudden cardiac death than people who do not have HIV, especially if the virus is not well-controlled or if they have other heart disease risk factors.

8 Sep 2021

Stanford researchers engineer an efficient, multi-purpose, mini CRISPR system

The common analogy for CRISPR gene editing is that it works like molecular scissors, cutting out select sections of DNA. Stanley Qi, assistant professor of bioengineering at Stanford University, likes that analogy, but he thinks it's time to reimagine CRISPR as a Swiss Army knife.

4 Sep 2021

Shorter survival of multiple myeloma subgroup linked to worse kidney damage

Nearly 20% of patients with multiple myeloma have a form in which they make extreme quantities of one component of the abnormal antibody they are producing, and these so-called "free monoclonal light chains" pile up and damage the kidneys, investigators say.

31 Aug 2021

Researchers identify 55 lingering effects of COVID-19

As COVID-19 hospitalizations once again soar in a fourth surge more than 18 months after the pandemic started, some patients continue to experience symptoms long after recovering from COVID, according to a Houston Methodist study recently published in Nature's Scientific Reports.

30 Aug 2021

Large Israeli study offers detailed look at safety profile of mRNA vaccine against SARS-CoV-2

A deep look into a nationwide mass vaccination setting in Israel revealed that the BNT162b2 (Pfizer–BioNTech) vaccine is not linked with an elevated risk of a majority of the adverse events under study, with the exception of myocarditis. However, even that potentially severe adverse event is much more pervasive following the infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), found a new study published in the New England Journal of Medicine (NEJM).

30 Aug 2021

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Combining a histone deacetylase inhibitor drug with immunotherapy agents is safe, and may benefit some patients with advanced cancers that have not responded to traditional therapy, according to results of a phase 1 clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center, Bloomberg~Kimmel Institute for Cancer Immunotherapy and several other centers including University of Pittsburgh Cancer Institute, Yale Cancer Center and City of Hope in Los Angeles, which participated in study enrollment, and the University of Southern California and University College Cork in Ireland, which collaborated on analysis of the data.

16 Aug 2021

Anemia News and Research

Further Reading

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

Gene therapy strategy against Angelman syndrome shows early promise

Red blood cells play a much larger role in the immune system than previously thought

Millets can play a promising role in preventing and reducing iron deficiency anemia, study shows

Better clinical outcomes in COVID-19 and vaccine-related myocarditis than classic myocarditis in children

Nearly 20% of adults have elevated troponin levels after major non-cardiac surgery

Small sachet of fortified food-based supplement could promote healthy development of children

Review describes nutritional imbalances in adults with celiac disease following a gluten-free diet

Penn scientists win 2021 Lasker Award for the discovery of therapeutic mRNA technology

Potential covalent SARS-CoV-2 spike protein inhibitors

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients

Combination of chemotherapy and immune checkpoint inhibitors shows promise in NSCLC patients with untreated brain metastases

Physical exercise can improve cancer-induced anemia

People living with HIV have higher risk of sudden cardiac death, finds study

Stanford researchers engineer an efficient, multi-purpose, mini CRISPR system

Shorter survival of multiple myeloma subgroup linked to worse kidney damage

Researchers identify 55 lingering effects of COVID-19

Large Israeli study offers detailed look at safety profile of mRNA vaccine against SARS-CoV-2

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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