Angiotensin News and Research

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Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.

Research probes interaction between SARS-CoV-2 and influenza

Researchers from Germany and France tried to determine if epidemiological studies based on co-detection prevalence data can offer a reliable estimation of interactions among respiratory viruses. They designed a simulation study by building on a general epidemiological model of co-circulation of 2 respiratory viruses that cause seasonal epidemics.

8 Sep 2021

The role of nanobodies in capturing and containing SARS-CoV-2

Scientists have repurposed the Nb Ty1 for the detection and neutralization of SARS-CoV-2.

8 Sep 2021

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

A new study successfully identifies a series of inhibitors that possesses pancoronavirus activity against SARS-CoV, SARS-CoV-2, and MERS-CoV.

7 Sep 2021

Maternal SARS-CoV-2 vaccination in early-third trimester may optimize neonatal seroprotection

Researchers in Israel have conducted a study showing that vaccinating pregnant women against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) early on in the third trimester may maximize transplacental antibody transfer, potentially helping to prevent severe coronavirus disease 2019 (COVID-19) during infancy.

6 Sep 2021

Study sheds light on neurologic symptoms caused by SARS-CoV-2 infection

Researchers in Australia and Finland have provided important insights into how infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – might affect nervous system circuitries and cause neurologic symptoms.

6 Sep 2021

Is the SARS-CoV-2 Lambda variant more vaccine-resistant than the Delta variant?

Researchers in the USA and China recently published a report in which they discussed the potential factors that confer high infectivity and immune resistance on the Delta and Lambda variants.

6 Sep 2021

Study finds a restricted number of possible escape mutations for SARS-CoV-2 Delta variant

The emergence of escape mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is somewhat less likely for the Delta variant in comparison with the original or wild type virus, shows a recent study currently available on the bioRxiv* preprint server while it undergoes peer review.

5 Sep 2021

SARS-CoV-2 fusion peptides play distinct roles according to neutron scattering

A new study determines the physical and thermodynamic events associated with the interactions that lead to the fusion between SARS-CoV-2 and the host.

5 Sep 2021

Efficacy of vaccines against the SARS-CoV-2 Delta variant

A new study uses statistical models to determine vaccine efficacy against the various SARS-CoV-2 variants and clinical endpoints for SARS-CoV-2 variants.

5 Sep 2021

Hypopituitarism and COVID-19 – exploring a possible bidirectional relationship?

In a recent study published in Reviews in Endocrine and Metabolic Disorders, the researchers discuss the extra-pulmonary manifestations of COVID-19.

5 Sep 2021

Impact of colloidal aggregation in COVID-19 drug repurposing screens

A recent study investigated the influence of colloidal aggregation on early drug development in repurposing screens

3 Sep 2021

Antibody cocktail neutralizes SARS-CoV-2 and has projected protection up to 12 months

A new study reports long-lasting, effective protection against severe disease with the AZD7442 antibody cocktail.

3 Sep 2021

Should pregnant women be vaccinated against COVID-19?

A recent study examines whether COVID-19 risks in pregnant women justify the administration of COVID-19 vaccines to pregnant individuals.

2 Sep 2021

Risk of COVID-19 transmission from animals to older adults

A new study in the journal GeroScience deals with this aspect of the disease, especially with respect to preventing higher death rates in older adults.

2 Sep 2021

An assessment of post-vaccination immune response to SARS-CoV-2 Delta in elderly and health care workers

A new cohort study comparing immune responses among vaccinated elderly persons and healthcare workers has been conducted.

2 Sep 2021

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

A new study published in mBio discusses the microevolution of SARS-CoV-2.

31 Aug 2021

The tale of mRNA vaccines: Turning calamity into opportunity

In a review paper published in the journal Nature Reviews, researchers from Carnegie Mellon University and the University of Pennsylvania have described the underlying technologies for mRNA vaccines and their future prospects with improved delivery systems and applications in diseases beyond the ongoing COVID-19 pandemic.

31 Aug 2021

Role of glycans on the SARS-CoV-2 spike protein in human receptor interaction

A team of investigators, led by Dr. Benjamin F. Mann, from Merck, USA have published a new study on the preprint server bioRxiv*. They have used a biochemical approach to control the glycosylation profile of the S protein receptor-binding domain (RBD) and to analyze the effect of different glycosylation patterns on receptor binding.

30 Aug 2021

Will mRNA vaccine boosters be required for SARS-CoV-2 variants?

A new study shows that the highly effective mRNA Moderna vaccine designed against the original SARS-CoV-2 strain may lose some efficacy as new variants arise.

30 Aug 2021

Could genetic variants in host cell receptors (ACE2) explain COVID-19 susceptibility among certain ethnic groups?

Led by Ioannis Karakikes of Stanford University, a new study suggests some hospitalized patients with COVID-19 contain ACE2 genetic variants that increase ACE2 expression. Some variants that altered ACE2 protein expression and binding affinity were more prevalent in people with European backgrounds.

30 Aug 2021