Angiotensin Converting Enzyme 2 News and Research

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Convalescent plasma post-vaccination increases binding and neutralizing antibodies against SARS-CoV-2 variants

A recent study assesses the boost in antibodies against SARS-CoV-2)variants post-vaccination in plasma samples from previously infected COVID-19 patients.

7 Nov 2021

“Catching SARS-CoV-2 in the act” – viral infection of nasal mucosa spares nerve cells

A new study discusses the entry of SARS-CoV-2 into the respiratory and olfactory mucosa of the nasal cavity.

4 Nov 2021

SARS-CoV-2 detected in white-tailed deer with possible zooanthroponotic spillover events

The study aimed to test the hypothesis that the infection and transmission of SARS-CoV-2 of deer occurred in nature.

4 Nov 2021

Pre-clinical follow-up study boosting with original formulation and next generation INO-4802 SARS-CoV-2 vaccine candidate

Researchers describe the antibody-inducing effects of DNA-based synthetic vaccines INO-4800 and INO-4802 against SARS-CoV-2 in non-human primates.

3 Nov 2021

Impact of SARS-CoV-2 infection on human semen quality

A new review article aimed to extract, review and summarize these articles from the mentioned databases to determine the link between SARS-CoV-2 infection and semen quality.

3 Nov 2021

Anti-inflammatory diets in COVID-19

A recent review of research published in the journal Diseases has shown that anti-inflammatory diets can be useful in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or reducing the severity of coronavirus disease 2019 (COVID-19).

3 Nov 2021

SARS-CoV-2 neutralizing antibodies discovered in a 20-year-old human antibody library

In an article published in the open-access journal Advance Engineering, a multinational team of researchers reported the selection and characterization of 3 potent SARS-CoV-2 antibodies - S-E6, S-B8, and S-D4 - from a pre-COVID-19 human combinatorial antibody library that was established 20 years ago.

3 Nov 2021

Isolation of potent neutralizing monoclonal antibodies using nanoparticles displaying SARS-CoV-2 S glycoprotein

A new study aimed to identify several potent neutralizing RBD-directed and NTD-directed mAbs that used a nanoparticle displaying the S glycoprotein to capture SARS-CoV-2-specific B cells.

2 Nov 2021

Identification of common genes in COVID-19 and COPD

Based on protein-protein interactions, the paper shows the presence of ten genes that overlap between the two illnesses, also shared by several other deadly and debilitating diseases.

2 Nov 2021

Placental cell-type productively infected with SARS-CoV-2

A new preprint describes the development of a new platform for evaluating the risk of SARS-CoV-2 infection in placental tissue.

2 Nov 2021

SARS-CoV-2 variants neutralized by camel nanobodies

Researchers from the US recently isolated two VHH nanobodies - 7A3 and 8A2 - from dromedary camels (Camelus dromedaries) using phage display. These nanobodies were found to have a high affinity for the spike RBD and broad neutralization abilities against SARS-CoV-2 and its variants.

2 Nov 2021

Curcumin, a bioactive component of turmeric, effectively neutralizes SARS-CoV-2 in vitro

The researchers investigated the neutralizing activity of turmeric root extract, curcumin-containing capsules, and pure curcumin against SARS-CoV-2.

1 Nov 2021

Study finds inhaled microspheres reduce SARS-CoV-2 infective effectiveness

A new study develops an inhaled microfluidic microsphere with a genetically engineered membrane from the ACE2 receptor-overexpressing cells and macrophages.

1 Nov 2021

The impact of SARS-CoV-2 variants on the COVID-19 epidemic in South Africa

A new study explores the role of new SARS-CoV-2 variants in sustaining the pandemic in South Africa.

31 Oct 2021

New Canadian serology solution for SARS-CoV-2 infections and vaccination

A new study developed a “Made-in-Canada” solution for enabling scalable and reproducible SARS-CoV-2 serology.

31 Oct 2021

The ability of natural flavonoids to inhibit SARS-CoV-2

A recent systematic review discusses naturally occurring flavonoids as a promising antiviral alternative against SARS-CoV-2.

31 Oct 2021

Structure of human-infecting canine coronavirus HuPn-2018 spike glycoprotein

As CCoV-HuPn-2018 has been recently isolated in a child's respiratory swab, researchers from the University Of Washington have been examining the structure of the virus.

28 Oct 2021

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

A new study identifies a potent SARS-CoV-2 antiviral, Pheophorbide a (PheoA), which is a compound derived from the plant Marchantia polymorpha L.

27 Oct 2021

The difference in the dynamics of SARS-COV-2 variants

A new study provides a detailed description of the varying interactions between SARS-CoV-2 and the host cell ACE-2 receptor.

27 Oct 2021

Taking lessons in molecular therapeutics from earthworms to combat COVID

Scientists were interested in further investigating the defense mechanism of earthworms in an effort to discover therapeutic solutions against SARS-CoV-2.

27 Oct 2021