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New clues may help explain why some people are more susceptible to stress than others

UT Southwestern Medical Center researchers have found new clues that might help explain why some people are more susceptible to stress than others.

31 Mar 2010

Study suggests two distinct versions of multiple sclerosis

There may be two distinct versions of multiple sclerosis, a study in both animal models and human blood samples suggests. What's more, a patient's responsiveness to the most popular first-line drug for this episodic and all-too-often recurring autoimmune condition seems to depend on which version that patient has.

30 Mar 2010

Inovio Biomedical's total revenue increased to $2.6M for quarter ended December 31, 2009

Inovio Biomedical Corporation today reported financial results for the quarter and year ended December 31, 2009.

29 Mar 2010

UAB researchers discover first bio-marker for MS

Researchers at the University of Alabama at Birmingham have found the first bio-marker for multiple sclerosis that might predict which patients will respond to a standard therapy and which will not.

29 Mar 2010

Inflamed tissues linked to increased production of protein involved in pain signaling

Using a novel animal model to study craniofacial pain, researchers at Oregon Health & Science University's School of Dentistry have discovered that when tissues are inflamed, the nerve cells carrying pain information from the head to the brain produce in large quantities a protein involved in pain signaling.

26 Mar 2010

New devices pave way for applications in cardiology and neurology

A team of cardiologists, materials scientists, and bioengineers have created and tested a new type of implantable device for measuring the heart's electrical output that they say is a vast improvement over current devices. The new device represents the first use of flexible silicon technology for a medical application.

26 Mar 2010

Stretchable electronic device holds promise for treating irregular heart rhythms

The electronics can bend, stretch and twist. No small feat. Now the flexible and stretchable electronics can map waves of electrical activity in the heart with better resolution and speed than that of conventional cardiac monitoring technology.

24 Mar 2010

Ultraviolet portion of sunlight may play bigger role in controlling MS: Study

For more than 30 years, scientists have known that multiple sclerosis (MS) is much more common in higher latitudes than in the tropics. Because sunlight is more abundant near the equator, many researchers have wondered if the high levels of vitamin D engendered by sunlight could explain this unusual pattern of prevalence.

23 Mar 2010

Effective defense against HIV: Acne drug minocycline

Johns Hopkins scientists have found that a safe and inexpensive antibiotic in use since the 1970s for treating acne effectively targets infected immune cells in which HIV, the virus that causes AIDS, lies dormant and prevents them from reactivating and replicating.

20 Mar 2010

Acne drug prevents HIV breakout

18 Mar 2010

Bone marrow stem cells offer potential treatment for patients with peripheral arterial disease

Bone marrow stem cells suspended in X-ray-visible microbubbles dramatically improve the body's ability to build new blood vessels in the upper leg-providing a potential future treatment for those with peripheral arterial disease or PAD, say researchers at the Society of Interventional Radiology's 35th Annual Scientific Meeting in Tampa, Fla.

18 Mar 2010

New findings promise to have fundamental significance in the fight against cancer

Cells have two different protection programs to safeguard them from getting out of control under stress and from dividing without stopping and developing cancer. Until now, researchers assumed that these protective systems were prompted separately from each other.

18 Mar 2010

Novel procedure opens door to new and future treatment for pancreatic cancer

Pancreatic cancer-known as the most fatal cancer with no known effective treatment-requires a radical new therapy. A promising approach may come in the form of tiny gold nanoparticles-loaded with a therapeutic agent to kill cancer-in a novel procedure called "nanoembolization," said researchers at the Society of Interventional Radiology's 35th Annual Scientific Meeting in Tampa, Fla.

17 Mar 2010

Viron Therapeutics' VT-346 anti-TNF protein exhibits positive results in transgenic mouse model for arthritis

Viron Therapeutics Inc. announced that VT-346, an anti-TNF protein therapeutic, demonstrated positive results in a pivotal proof of concept study in the gold standard transgenic mouse model for arthritis. VT-346 achieved a statistically significant, dose dependent impact in this preclinical model of arthritis and prevented deterioration due to disease in terms of weight gain, arthritic score and pathology parameters. VT-346 had particularly strong protective effects on therapeutically-important bone and cartilage damage in this model.

16 Mar 2010

Cytheris study: rhIL-7 treatment restores T cell trafficking and improves survival in animal model of sepsis

Cytheris SA, a clinical stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced publication of data from a preclinical study in a clinically relevant animal model of sepsis showing that recombinant human Interleukin-7 (rhIL-7) treatment not only restores T cell trafficking and function, but also translates into improved survival.

16 Mar 2010

MMG effectively locates nerves during minimally invasive spine surgery

An electronic device is an accurate technique for locating and avoiding nerves during spinal procedures, suggests a study by Henry Ford Hospital researchers.

16 Mar 2010

Sigma-Aldrich and Pfizer sign new agreement

Sigma-Aldrich® today announced that it has entered into an agreement with Pfizer under which Sigma-Aldrich will sell approximately 100 Pfizer-developed small molecule compounds to life science researchers for target characterization, assay development, screening and in vivo animal model applications.

15 Mar 2010

XOMA 052 reduces adverse consequences that lead to development of congestive heart failure

XOMA Ltd., a leader in the discovery and development of antibody therapeutics, announced results demonstrating that a murine equivalent of XOMA 052, its novel, high-affinity antibody to interleukin-1 beta (IL-1 beta), significantly reduced adverse consequences that usually lead to the development of congestive heart failure in a mouse model of acute myocardial infarction (heart attack).

15 Mar 2010

GTC Biotherapeutics reports total net loss of $1.7M for fourth-quarter 2009

GTC Biotherapeutics, Inc. today reported its financial results for the fourth quarter and fiscal year ended January 3, 2010. The total net loss for the fourth quarter was $1.7 million, or $0.09 per share, compared with $6.2 million, or $0.60 per share, for the fourth quarter of 2008. The total net loss for 2009 was $27.9 million, or $2.18 per share, compared to $22.7 million, or $2.31 per share, for 2008.

12 Mar 2010

Independently-conducted studies confirm significant bioavailability of orally delivered insulin

ACCESS PHARMACEUTICALS, INC. announced that it has received reports of significant bioavailability of orally delivered insulin in two independently-conducted animal studies. The studies, which confirm earlier findings, were performed as part of on-going work with commercial collaborators that are evaluating Access' Cobalamin™ Oral Drug Delivery Technology.

12 Mar 2010

Animal Model News and Research

New clues may help explain why some people are more susceptible to stress than others

Study suggests two distinct versions of multiple sclerosis

Inovio Biomedical's total revenue increased to $2.6M for quarter ended December 31, 2009

UAB researchers discover first bio-marker for MS

Inflamed tissues linked to increased production of protein involved in pain signaling

New devices pave way for applications in cardiology and neurology

Stretchable electronic device holds promise for treating irregular heart rhythms

Ultraviolet portion of sunlight may play bigger role in controlling MS: Study

Effective defense against HIV: Acne drug minocycline

Acne drug prevents HIV breakout

Bone marrow stem cells offer potential treatment for patients with peripheral arterial disease

New findings promise to have fundamental significance in the fight against cancer

Novel procedure opens door to new and future treatment for pancreatic cancer

Viron Therapeutics' VT-346 anti-TNF protein exhibits positive results in transgenic mouse model for arthritis

Cytheris study: rhIL-7 treatment restores T cell trafficking and improves survival in animal model of sepsis

MMG effectively locates nerves during minimally invasive spine surgery

Sigma-Aldrich and Pfizer sign new agreement

XOMA 052 reduces adverse consequences that lead to development of congestive heart failure

GTC Biotherapeutics reports total net loss of $1.7M for fourth-quarter 2009

Independently-conducted studies confirm significant bioavailability of orally delivered insulin

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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