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Researchers uncover how brown fat cells increase metabolic activity

Special fat cells known as brown adipocytes help maintaining body temperature by converting calory-rich nutrients into heat.

16 Sep 2024

Breakthrough in understanding formaldehyde toxicity during development and aging

AMeD syndrome is a severe genetic condition found in children that present with accelerated aging, global developmental delay and bone marrow failure, among others, progressing to Myelodysplastic Syndrome and Acute Myeloid Leukaemia.

13 Sep 2024

The potential benefits of aged black garlic on inflammation and prostate cancer

Researchers investigate the anti-inflammatory and anti-prostate cancer properties of aged black garlic extract.

13 Sep 2024

Nucleophagy identified as key DNA repair mechanism in cancer treatments

A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is particularly relevant for patients undergoing colorectal cancer treatments.

12 Sep 2024

Ropirio Therapeutics secures exclusive license for novel lymphatic system activators

The Wyss Institute at Harvard University announced today that Ropirio Therapeutics, Inc. (Ropirio) has secured a worldwide, exclusive license from Harvard's Office of Technology Development (OTD) and Boston University (BU)'s Technology Development office for novel molecules that activate the lymphatic system - a first in the pharma industry.

11 Sep 2024

Study links periodontal bacteria to worsening rheumatoid arthritis

Periodontal disease, which affects the gums and tissues that surround the teeth, is one of the most prevalent dental conditions worldwide.

5 Sep 2024

Immune cells prevent the lungs' protective barrier from healing after viral infections

Investigators involved in a multicenter study co-led by Cedars-Sinai discovered a pathway by which immune cells prevent the lungs' protective barrier from healing after viral infections like COVID-19.

4 Sep 2024

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia and bone marrow failure disorders.

2 Sep 2024

Study explores link between prostate cancer treatment and Alzheimer’s disease

Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem.

29 Aug 2024

The critical role of PGK1 in Parkinson's disease

An enzyme called PGK1 has an unexpectedly critical role in the production of chemical energy in brain cells, according to a preclinical study led by researchers at Weill Cornell Medicine. The investigators found that boosting its activity may help the brain resist the energy deficits that can lead to Parkinson's disease.

21 Aug 2024

Ketogenic diet can boost efficacy of pancreatic cancer therapy

A study of fasting and the ketogenic diet reveals a new vulnerability of pancreatic tumors to an existing cancer drug.

14 Aug 2024

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

Study demonstrates that a novel prime/boost vaccination protocol using live-attenuated influenza vaccines effectively induces strong immune responses in pigs, offering a promising approach for future influenza vaccination strategies.

13 Aug 2024

New ultrasound-based tool offers precise measurement of lung diseases

Researchers have established a suite of parameters that can be determined using ultrasound to quantitatively measure different physical characteristics of the lung.

13 Aug 2024

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

Using zebrafish "Avatars", an animal model developed by the Cancer Development and Innate Immune Evasion lab at the Champalimaud Foundation (CF), led by Rita Fior, Mayra Martínez-López – a former PhD student at the lab now working at the Universidad de las Américas in Quito, Ecuador – and colleagues studied the initial steps of the Bacillus Calmette-Guérin (BCG) vaccine's action on bladder cancer cells.

8 Aug 2024

New $11.3 million grant to explore endothelial cell dysfunction in cardiovascular disease

With a new $11.3 million Program Project grant from the National Institutes of Health, experts from the Vascular Biology Center at the Medical College of Georgia at Augusta University are working to better understand the underlying mechanisms of cardiovascular disease.

8 Aug 2024

Animal Model News and Research

Researchers uncover how brown fat cells increase metabolic activity

Breakthrough in understanding formaldehyde toxicity during development and aging

The potential benefits of aged black garlic on inflammation and prostate cancer

Nucleophagy identified as key DNA repair mechanism in cancer treatments

Ropirio Therapeutics secures exclusive license for novel lymphatic system activators

Study links periodontal bacteria to worsening rheumatoid arthritis

Immune cells prevent the lungs' protective barrier from healing after viral infections

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Study explores link between prostate cancer treatment and Alzheimer’s disease

The critical role of PGK1 in Parkinson's disease

Ketogenic diet can boost efficacy of pancreatic cancer therapy

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

New ultrasound-based tool offers precise measurement of lung diseases

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

New $11.3 million grant to explore endothelial cell dysfunction in cardiovascular disease

New bioactive material regenerates high-quality cartilage in the knee joints of large-animal model

Vanderbilt researchers illuminate white matter signals in the spinal cord

UVA researchers identify a potential treatment for respiratory symptoms of long COVID

Researchers identify a potential therapeutic target for advanced multiple sclerosis

New study helps better understand the pathology of fatty liver disease MASH

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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