Animal Model News and Research

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Does the heart contain stem cells that are self-renewing?

If you've ever used a loofah in the shower, you've stirred up some stem cells. As the outer layer of skin sloughs off, stem cells in the dermis rush to repair and replace those buffed away.

21 Jul 2005

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

In a ground-breaking study, scientists at Children's Hospital of Pittsburgh have discovered that adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply, a previously unknown characteristic indicating that post-natal stem cells may play an important therapeutic role.

27 Jun 2005

Gleevec or similar drugs might be useful in preventing adverse side effects of smallpox vaccine

Mice given a relatively new cancer drug can survive an otherwise lethal dose of vaccinia virus, a relative of smallpox virus, report scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID).

27 Jun 2005

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

27 Jun 2005

Foxp2 gene plays an essential role in the development of social communication

The association between Foxp2 and language was first identified in a family in which half the members had severe speech and grammar impairments. Studies showed that all the affected family members had a mutation in the Foxp2 gene.

21 Jun 2005

Australian scientists develop unique animal model for asthma

The State Government of Victoria, Australia has announced that Melbourne veterinary scientists have developed a unique animal model for asthma that may help drug companies fast track the creation of therapies for the disease.

19 Jun 2005

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer’s disease have an immune defect making it difficult to clean away these wastes.

From MP Biomedicals, LLC 10 Jun 2005

A promising animal model demonstrates course of epilepsy

A promising animal model of epilepsy became even more valuable with the demonstration that the course of the disorder closely parallels that of one of the most common forms of epilepsy in humans.

6 Jun 2005

Triple approach is promising against cancer cells

A trimodal treatment strategy combining chemotherapy, radiation therapy, and a protein kinase inhibitor is much more effective against cancer cells than any combination of only two treatment methods.

1 Jun 2005

Is winter flu worse because of exercise-induced 'window of susceptibility'?

When you exercise or work outside in winter, that dry feeling at the back of your throat indicates the cold air has irritated your throat. Racehorses share a similar experience: exercising in below-freezing air causes mild airway injury.

26 May 2005

Brain fatty acid levels linked to depression

A group of researchers from Israel has discovered that rats exhibiting the signs of depression have increased levels of the omega-6 fatty acid, arachidonic acid, in their brains. The details of their findings appear in the June issue of the Journal of Lipid Research, an American Society for Biochemistry and Molecular Biology journal.

25 May 2005

Ceramide can be administered through the blood stream to target and kill cancer cells

A Penn State College of Medicine study shows for the first time in an animal model that ceramide, a naturally occurring substance that prevents the growth of cells, can be administered through the blood stream to target and kill cancer cells.

25 May 2005

Researchers generate patient-specific stem cells

Researchers have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury.

20 May 2005

Disease progression model of pancreatic cancer developed

Building on previous work, researchers at the University of Pennsylvania School of Medicine have developed an animal model of pancreatic cancer that closely mimics disease progression in humans. From this, they hope to develop new treatments for this deadly disease.

20 May 2005

Cataract treatment in the blink of an eye

Researchers at the University of Canterbury, New Zealand are pioneering the development of an eye drop to halt the development of cataracts.

10 May 2005

Antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system

By studying animals, Johns Hopkins researchers have discovered that the antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body.

1 May 2005

Physical activity appears to inhibit Alzheimer's

Physical activity appears to inhibit Alzheimer's-like brain changes in mice, slowing the development of a key feature of the disease, according to a new study.

26 Apr 2005

P12 protein influences key cell-signaling pathway

New research shows that a protein produced by a cancer-causing virus influences a key signaling pathway in the immune cells that the virus infects. This stimulates the cells to divide, helping the virus spread through the body.

26 Apr 2005

Body's 24-hour internal clock linked to obesity and diabetes

Obesity and diabetes in both adults and children are rising at alarming rates and a wide range of culprits -- super-sized food portions, lack of exercise due to television, computers, suburban sprawl and loss of gym classes, high-fat and fast foods, sugar-laden drinks and psychological trauma -- have been blamed.

21 Apr 2005