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Researchers discover new biological mechanism to regenerate and repair myelin

A study led by Dr. Hyun Kyoung Lee, associate professor at Baylor College of Medicine and investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, has discovered a new biological mechanism to regenerate and repair myelin, a protective sheath that insulates neuronal fibers and plays a vital role in ensuring rapid and accurate neurotransmission.

24 Aug 2023

Diabetes drug promotes longevity by stimulating the body's production of ether lipids

Metformin, the most commonly used drug to treat type 2 diabetes, not only lowers blood sugar levels but has revealed to extend lifespan in C. Elegans -- an animal model that shares similar metabolic systems with humans and are often used to model human diseases.

23 Aug 2023

Artificial intelligence and polyclonal antibody sequencing redefine the future of antibody discovery

In this interview, News-Medical had the opportunity to speak with Dr. Xiaobing Han, Principal Scientist for Antibody Discovery at Rapid Novor.

From Rapid Novor Inc 23 Aug 2023

Sleep dysfunction is underreported and underrecognized in Huntington's disease

A good night's sleep is essential for everyone. In individuals with Huntington’s disease (HD), sleep disturbances constitute an additional burden that may exacerbate disease outcomes and impact patients’ quality of life.

21 Aug 2023

Can nutritional interventions positively impact psoriasis severity?

Improvement in psoriasis (Ps) through nutritional strategies.

15 Aug 2023

Virginia Tech researchers receive $2.6M NIH grant to study new pancreatic cancer treatment

Only about 10 percent of patients survive as long as five years after a diagnosis of pancreatic cancer.

14 Aug 2023

Scientists develop novel animal model of neurobrucellosis

Neurobrucellosis is a severe long-term complication of brucellosis, one of the most common bacterial zoonotic diseases.

10 Aug 2023

Scientists discover a therapeutic target for Alzheimer's disease

Scientists at Université Laval and the University of Lethbridge have succeeded in reversing certain cognitive manifestations associated with Alzheimer's disease in an animal model of the disease.

10 Aug 2023

UTHSC professor receives $2.56 million to continue glioblastoma research

Lawrence Pfeffer, PhD, Professor in the Department of Pathology at the University of Tennessee Health Science Center, recently was awarded $2.56 million from the National Cancer Institute over the next five years to identify and target molecular pathways that will enhance glioblastoma's sensitivity to currently approved drug therapies.

7 Aug 2023

NCI funds study to investigate the underlying cellular mechanisms that drive ER+ breast cancer

The National Cancer Institute (NCI) has awarded a 5-year, $2.7 million grant to researchers at Sanford Burnham Prebys to investigate and elucidate the underlying cellular mechanisms that drive the most common form of breast cancer.

7 Aug 2023

Can vitamin D have positive effects on reducing cortical pathology, oxidative stress, and neurofilament light chain serum levels?

Researchers use an established murine model of cortical inflammatory demyelination to investigate the effects of vitamin D.

2 Aug 2023

How effective is physical activity in alleviating obesity-related inflammation in diabetes?

Scientists determine whether physical activity can be used as an effective intervention to mitigate obesity-related inflammation in diabetes.

1 Aug 2023

Stem cells offer new hope for Crohn's disease treatment

Research from Ann & Robert H. Lurie Children's Hospital of Chicago found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn's disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage.

28 Jul 2023

Researchers make breakthrough in fight against mucosal melanoma

Although rare, mucosal melanoma in humans has a low survival rate. It has been difficult to investigate due to a lack of similar cancers in animals for study.

26 Jul 2023

Biomimetic materials pulsed with low-energy blue light can reshape damaged corneas

An injectable biomaterial activated by pulses of low-energy blue light has tremendous potential for on-the-spot repair to the domed outer layer of the eye, a team of University of Ottawa researchers and their collaborators have revealed.

26 Jul 2023

Brazilian researchers identify new way to stop excessive inflammation in COVID-19

Researchers at the University of São Paulo (USP) in Brazil have identified a new class of molecules capable of stopping the excessive inflammation typical of the severe form of COVID-19 without impairing the immune response to SARS-CoV-2, the virus that causes the disease.

25 Jul 2023

Single target, multiple possibilities: microRNA holds promise for epilepsy treatment

Study investigated the role of micro-ribonucleic acid (miRNA) miR-335-5p as a potential therapeutic target for epilepsy.

25 Jul 2023

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world. But many people would be surprised to learn that this painting offers the first evidence of a disease called familial hypercholesterolemia (FH).

20 Jul 2023

Intensive exercise slows the course of Parkinson's disease, study finds

Neuroscientists from the Faculty of Medicine of the Catholic University, Rome Campus, and the A. Gemelli IRCCS Polyclinic Foundation found that intensive exercise could slow the course of Parkinson's disease and described the biological mechanisms.

14 Jul 2023

Primate brain cell atlas provides molecular and cellular basis for neural circuit research

A team of nearly 100 scientists recently mapped the cell-type taxonomy in the macaque cortex and revealed the relationship between cell-type composition and various primate brain regions by using the self-developed spatial transcriptome sequencing technology Stereo-seq and snRNA-seq technology, which provides a molecular and cellular basis for further investigation into neural circuits.