Antibodies News and Research

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Study reveals developmental changes of the immune system during first week of life

Within the womb, a human fetus benefits from the protection of the placenta, limiting their contact with pathogens.

22 Oct 2020

New model could help identify people at risk for long COVID

Researchers in the UK, United States, and Sweden have presented new findings that could help identify individuals at risk of "long COVID" – a protracted course of coronavirus disease 2019 (COVID-19) symptoms last for more than 28 days.

22 Oct 2020

Study shows how genetic predisposition contributes to the development of multiple sclerosis

About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study led by the University of Zurich has now shown how this genetic predisposition contributes to the development of the autoimmune disease multiple sclerosis in combination with environmental factors.

22 Oct 2020

Study may pave way for more effective treatment for Hepatitis C

Virologists at Institut national de la recherche scientifique (INRS) have identified a critical role played by a cellular protein in the progression of Hepatitis C virus infection, paving the way for more effective treatment.

22 Oct 2020

Monoclonal Antibodies: Discovery, Characterization and Challenges

In this interview, News-Medical talks to David Apiyo, a senior manager of applications at Sartorius AG, about monoclonal antibody development and characterization.

22 Oct 2020

"Immunological imprinting" could influence antibody response to COVID-19

Researchers in the United States and Spain have shown that prior exposure to seasonal coronaviruses may influence antibody responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative agent of coronavirus disease 2019 (COVID-19).

21 Oct 2020

Study shows SARS-CoV-2 uses a receptor to efficiently infect human cells

To efficiently infect human cells, SARS-CoV-2, the virus that causes COVID-19, is able to use a receptor called Neuropilin-1, which is very abundant in many human tissues including the respiratory tract, blood vessels and neurons.

21 Oct 2020

3D imaging of SARS-CoV-2 infection in ferrets using light sheet microscopy

Researchers from the Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health demonstrate the ability to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in 3D tissue samples in ferrets. This will allow the detection of infection patterns in tissues and their interrelations.

20 Oct 2020

New vaccine targeting toxic Aβ may offer clinical benefit in treating Alzheimer's disease

Our immune system's capacity to mount a well-regulated defense against foreign substances, including toxins, weakens with age and makes vaccines less effective in people over age 65.

20 Oct 2020

Engineered decoy receptor could protect against coronaviruses

Researchers in the United States have shown that an engineered soluble decoy receptor tightly binds the spike protein of severe acute respiratory syndrome (SARS)-associated viruses. This could potentially provide protection against zoonotic betacoronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

20 Oct 2020

Scientists are developing a point-of-care SARS-CoV-2 detection system based on photonic sensors

Detecting SARS-CoV-2 virus and related antibodies is essential to control the COVID-19 pandemic. A multidisciplinary team of scientists from the University of Malaga, led by Robert Halir, researcher of the Department of Communications Engineering of the Higher Technical School of Telecommunications Engineering, aware of the limitations of current techniques, are developing a point-of-care detection system based on photonic sensors.

20 Oct 2020

Can ordinary COVID patients get the Trump treatment? It’s OK to ask

When Terry Mutter woke up with a headache and sore muscles on a recent Wednesday, the competitive weightlifter chalked it up to a hard workout.

20 Oct 2020

Older males who have recovered from COVID-19 are best plasma donors for treatment

Sex, age, and severity of disease may be useful in identifying COVID-19 survivors who are likely to have high levels of antibodies that can protect against the disease, according to a new study co-led by researchers at Johns Hopkins Bloomberg School of Public Health.

20 Oct 2020

New inhaled treatment may lead to self-administered therapy for COVID-19

An inhaled treatment against the SARS-CoV-2 virus may lead to a future self-administered therapy for COVID-19, the pandemic that has killed more than 1 million people worldwide.

20 Oct 2020

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

The COVID-19 pandemic has led to intensive scientific efforts to bring about an effective vaccine for global distribution. Many different vaccine design approaches are underway. A recent study published in the journal The Lancet Infectious Diseases in October 2020 reports a potentially successful inactivated virus vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Oct 2020

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Now, a new study presented on the preprint server bioRxiv in October 2020 describes the efficient design of an mRNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), based on the use of the viral receptor-binding domain (RBD) mRNA encapsulated in lipid nanoparticles (LNP).

19 Oct 2020

UCLA professor named to the National Academy of Medicine

Dr. Antoni Ribas, a world-renowned physician-scientist and professor of medicine at the David Geffen School of Medicine at UCLA, has been named to the National Academy of Medicine, one of the highest honors in the fields of health and medicine.

19 Oct 2020

Antigenic imprinting of sarbecovirus

A recent study published on the preprint server bioRxiv* in October 2020 shows that the design of a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) must consider the prior history of exposure to coronaviruses since these affect the antibody response to the virus.

19 Oct 2020

New lab test for detection of SARS-CoV-2 antibodies gives results more quickly than existing assays

Knowing you have developed antibodies against the SARS-CoV-2 virus after recovering from COVID-19 doesn't tell you everything about your immunity.

19 Oct 2020

Immunoglobulin M ACE2 autoantibodies associated with severe COVID-19

As the COVID-19 pandemic progresses with little prospect of immediate relief, a recent study by Johns Hopkins University researchers published on the preprint server medRxiv* in October 2020 discusses the association of Immunoglobulin M (IgM) autoantibodies against the host receptor that binds severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with severe disease via vascular endothelial damage. This could help develop better therapies and prognostic criteria.

19 Oct 2020