Antibodies News and Research

RSS

Antibody-based Zika virus therapeutic protects monkeys from infection, study shows

Using blood samples from an individual previously infected with Zika virus, scientists funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, have developed an antibody-based Zika virus therapeutic that protected monkeys from infection.

5 Oct 2017

Monoclonal antibody “cocktail” inhibits Zika infection, study reveals

A collaborative study conducted by the Miller School of Medicine, University of Miami has revealed that a monoclonal antibody “cocktail” inhibited zika virus (ZIKV) infection in primates.

5 Oct 2017

New DNA-based Zika vaccine demonstrates safety and ability to elicit immune response

A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans, according to new research from the Perelman School of Medicine at the University of Pennsylvania, conducted in partnership with The Wistar Institute, Inovio Pharmaceuticals, and GeneOne Life Science, Inc.

5 Oct 2017

MRI and ultrasound can detect fetal brain damage caused by Zika in utero

Clinicians managing Zika-affected pregnancies should use magnetic resonance imaging (MRI) in addition to standard ultrasound (US) because the more detailed MRI images can reveal more extensive areas of damage to the developing fetal brain, according to research presented during IDWeek 2017.

4 Oct 2017

Novel microscopy technique can more accurately diagnose cancer than current methods

A novel microscopy technique to examine tumour tissue in three dimensions can more accurately diagnose cancer than current two-dimensional methods, according to a study conducted at Karolinska Institutet and Karolinska University Hospital in Sweden. The study is published in Nature Biomedical Engineering.

3 Oct 2017

Benefits of Biomarkers in Colorectal Cancer Treatment

Biomarkers fall into different categories: diagnostic biomarkers, are used to identify a disease; prognostic biomarkers, help clinicians to determine, for example, whether you're more likely to die or have problems with a disease; and there are some that can be used to inform treatment, to determine whether one therapy would be more successful than another.

2 Oct 2017

Scientists explore the reason behind impaired sense of smell in Parkinson's disease

The first symptom of Parkinson's disease is often an impaired sense of smell. This neurodegenerative disease primarily causes irreparable damage to nerve cells in a brain area involved in movement control.

30 Sep 2017

New paper-based test can diagnose Zika infection within 20 minutes

MIT researchers have developed a paper-based test that can diagnose Zika infection within 20 minutes. Unlike existing tests, the new diagnostic does not cross-react with Dengue virus, a close relative of the Zika virus that can produce false positives on many Zika tests.

27 Sep 2017

High-speed method generates mini-protein binders with potential to become new class of drugs

Scientists have created a high-speed method to generate thousands of different, small, stable proteins from scratch that can be custom-designed to bind to specific therapeutic targets.

27 Sep 2017

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Merck KGaA, Darmstadt, Germany, and Pfizer Inc. today announced that the Japanese Ministry of Health, Labor, and Welfare (MHLW) has approved BAVENCIO (avelumab, genetically recombinant Injection 200mg/mL for intravenous use) as the first and only treatment indicated for curatively unresectable Merkel cell carcinoma (MCC), a rare and aggressive cancer, in Japan.

27 Sep 2017

Cellular messaging mechanism could lead to new way of treating disease

A newly discovered cellular messaging mechanism could lead to a new way to deliver therapeutics to tissues affected by disease, according to a new study from Harvard T.H. Chan School of Public Health.

27 Sep 2017

Vaccine to prevent Lyme disease on the cards

Lyme disease is an infection that spreads with the bites of an infected tick. For the past four years, a vaccine to protect dogs from this disease has been available. Now, vaccinating humans against this disease has also become a possibility.

26 Sep 2017

Study: Antibody neutralizes dengue and Zika virus in mice

Brazil and other areas hardest hit by the Zika virus – which can cause babies to be born with abnormally small heads – are also home to dengue virus, which is spread by the same mosquito species.

25 Sep 2017

Triple-action antibody to be tested as HIV vaccine

Scientists from the National Institutes of Health (NIH) in collaboration with the pharmaceutical company Sanofi have engineered a three-pronged antibody that protected monkeys from two strains of Human Immunodeficiency Virus (HIV) better than the equivalent naturally occurring antibodies.

22 Sep 2017

New study shows how staph cells evade the body's immune system

For years, medical investigators have tried and failed to develop vaccines for a type of staph bacteria associated with the deadly superbug MRSA. But a new study by Cedars-Sinai investigators shows how staph cells evade the body's immune system, offering a clearer picture of how a successful vaccine would work.

21 Sep 2017

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Fungal infections represent an increasing health crisis, especially for immune-deficient patients. American scientists now report in the journal Angewandte Chemie that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action.

21 Sep 2017

Researchers design novel small antibody fragment with improved crystallizability

Antibodies are a powerful weapon system in defending our body against invaders such as bacteria and viruses. Each antibody consists of four polypeptide chains: two heavy chains and two light chains joined to form a Y-shaped molecule.

21 Sep 2017

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

20 Sep 2017

'Small intestinal permeable peptides' improve biopharmaceuticals absorption in digestive tract

Biopharmaceuticals, medium- and high-molecular weight biologically active macromolecules, are not easily absorbed by the small intestine, the main organ responsible for gastrointestinal absorption, resulting in a bottleneck for oral administration type biopharmaceutical development.

20 Sep 2017

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

In a multi-institutional collaborative study, scientists at The Wistar Institute and the Medical University of Vienna, Austria, have identified the role of tumor-infiltrating or tumor-associated B-cells ("TABs") in melanoma progression and resistance to targeted therapy.

20 Sep 2017

Antibodies News and Research

Antibody-based Zika virus therapeutic protects monkeys from infection, study shows

Monoclonal antibody “cocktail” inhibits Zika infection, study reveals

New DNA-based Zika vaccine demonstrates safety and ability to elicit immune response

MRI and ultrasound can detect fetal brain damage caused by Zika in utero

Novel microscopy technique can more accurately diagnose cancer than current methods

Benefits of Biomarkers in Colorectal Cancer Treatment

Scientists explore the reason behind impaired sense of smell in Parkinson's disease

New paper-based test can diagnose Zika infection within 20 minutes

High-speed method generates mini-protein binders with potential to become new class of drugs

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Cellular messaging mechanism could lead to new way of treating disease

Vaccine to prevent Lyme disease on the cards

Study: Antibody neutralizes dengue and Zika virus in mice

Triple-action antibody to be tested as HIV vaccine

New study shows how staph cells evade the body's immune system

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Researchers design novel small antibody fragment with improved crystallizability

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

'Small intestinal permeable peptides' improve biopharmaceuticals absorption in digestive tract

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

Immunology eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest Life Science News