Antibodies News and Research

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Cancer patients may one day benefit from treatment with mixtures of customized antibodies

In a study published recently in the Proceedings of the National Academy of Sciences (USA), a team of Weizmann Institute scientists have demonstrated how the right combination might form a web that destroys the cancer cell's communication network, ultimately demobilizing the cell.

22 Apr 2005

Experimental vaccine targeting West Nile virus

A small trial testing the safety of an experimental vaccine targeting West Nile virus (WNV) opened today at the National Institutes of Health's (NIH) Clinical Center in Bethesda, MD.

19 Apr 2005

Allergic diseases have increased

The rate of allergic diseases (atopy) in adults has steadily increased over the last quarter of the 20th century, but the reason for the increase is still unknown, according to a study published online by the BMJ.

19 Apr 2005

Researchers discover mechanism by which tumours support their own growth

In a recent issue of the American Journal of Pathology, the Bremen researchers report their findings on a signalling molecule called "High Mobility Group Protein B1" (HMGB1). As a signal sent by tumour cells HMGB1 proteins induce sprouting of blood vessels that supply tumours with oxygen, thus promoting tumour growth.

11 Apr 2005

Increased scrutiny of new multiple sclerosis-fighting drugs after Tysabri withdrawal

The removal of Tysabri from the market soon after its introduction is expected to increase scrutiny of other similar drugs in development for multiple sclerosis (MS), says ECRI, a leading, independent health services research agency.

11 Apr 2005

Malaria's secret weapon revealed

A US-led international team of scientists have discovered how the deadliest malaria parasite is able to "hide" from the body's immune system.

10 Apr 2005

Research helps understand how the malaria parasite disguises itself to avoid detection by the immune system

Scientists are making strides in understanding how the malaria parasite Plasmodium falciparum disguises itself to avoid detection by the immune system. The findings could lead to the development of new drugs for a disease that causes more than 300 million acute illnesses and at least one million deaths each year, most of them in developing countries.

7 Apr 2005

Infection with Chlamydia pneumoniae may increase the risk of heart attack in young men

Preliminary research suggests infection with Chlamydia pneumoniae may increase the risk of heart attack in young men, according to an article in the April 15 issue of Clinical Infectious Diseases.

7 Apr 2005

Epstein-Barr virus may increase risk of lupus

Almost everyone has been infected with Epstein-Barr virus (EBV), a member of the herpes family and one of the most common human viruses.

7 Apr 2005

EvoGenix expands capabilities through US acquisition

EvoGenix and Absalus own complementary technologies which, when combined, are capable of streamlining the identification of new antibody drug candidates and improving the development of safe and effective human therapeutic antibodies.

4 Apr 2005

Infants under one year of age can accept heart transplants from donors of different blood groups

A study showing that infants under one year of age can accept heart transplants from donors of different blood groups without the risk of organ rejection means a better chance of survival for infant patients and more efficient use of donor organs overall.

4 Apr 2005

Unravelling the Ebola virus’s biological cycle

Ebola virus infection in humans provokes a violent haemorrhagic fever. It usually flares up as intense epidemics. These kill 80 % of the people infected. Seven such outbreaks have hit Gabon and the Republic of Congo since 1994, leading to 445 cases resulting in 361 deaths.

4 Apr 2005

Tarvacin shows significant anti-viral activity

Peregrine Pharmaceuticals today announced that there will be two presentations, April 4 and 6, at the American Association of Immunologists (AAI) annual meeting in San Diego, California, indicating the anti-viral potential of its Tarvacin antibody. Dr. Melina Soares of The University of Texas Southwestern Medical Center at Dallas will present pre-clinical data titled "Targeting inside-out phospholipids on viruses in a guinea pig model of Lassa fever."

4 Apr 2005

Tumour Necrosis Factor alpha (TNF-alpha) blocking agents cause skin disease

Members of the second most important family of drugs used to treat rheumatoid arthritis can cause serious dermatological conditions in a quarter of patients under treatment, reveals a study published in the journal Arthritis Research and Therapy.

3 Apr 2005

Stress may enhance the body's ability to fight the flu

Short bouts of intense social stress improved the ability in the mice to recover from the flu. The stress apparently did so by substantially boosting the production of specialized immune cells that fought the virus.

3 Apr 2005

Surprising discovery about natural immunity to pneumococcus

Since 2000, U.S. infants have been routinely immunized against pneumococcal (Streptococcus pneumoniae) infection. Now, Boston researchers have made a surprising discovery about natural immunity to pneumococcus.

29 Mar 2005

New color-coded test for protein folding

Every protein--from albumin to testosterone--is folded into a unique, three-dimensional shape that allows it to function properly. Now Stanford University scientists have developed a simple test that instantly changes color when a protein molecule attached to a gold nanoparticle folds or unfolds.

28 Mar 2005

New therapy for treating cat allergies looks promising

Andrew Saxon, M.D., and a team of researchers at University of California, Los Angeles (UCLA) have found that a molecule designed to block cat allergies can prevent allergic reactions in laboratory mice and was also successful when tested on human cells in a test tube.

28 Mar 2005

New insights into Pemphigus

Pemphigus is a deadly skin blistering disease that occurs when patients' produce antibodies that attack proteins in their own cells – called autoantibodies.

28 Mar 2005

Antibodies from tobacco plants protect against anthrax

Scientists have produced, in tobacco plants, human antibodies that could be used to treat anthrax exposure. They reported their findings at the 2005 American Society for Microbiology Biodefense Research Meeting.

23 Mar 2005