Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

New antibody may offer effective drug treatment for breast cancer

An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks.

30 Oct 2023

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

The efficacy of the bivalent Pfizer-BioNTech COVID-19 messenger ribonucleic acid (mRNA) vaccine BNT162b2 BA.4/5.

30 Oct 2023

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

The role of anti-SARS-CoV-2 antibody levels on COVID-19 outcomes in patients with T2D.

30 Oct 2023

Redefining the battle against Alzheimer's with tau-focused treatments

Researchers explore the potential of tau-targeting therapies in treating Alzheimer's disease, focusing on immunotherapies and strategies to improve their efficacy. The study dives into the complex biology of tau proteins, their modifications, and how they can be targeted to halt the progression of Alzheimer's.

29 Oct 2023

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

AbbVie today announced that the UK Medicines and Healthcare products Regulatory Agency has granted conditional Marketing Authorisation for Tepkinly® (epcoritamab) as a monotherapy for the treatment of adults with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), after two or more systemic therapies.

28 Oct 2023

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compared to standard of care when offered a combination treatment of KRAS inhibitor sotorasib and monoclonal antibody panitumumab.

27 Oct 2023

A new era of vaccines leaves old questions about prices unanswered

The world is entering a new era of vaccines. Following the success of covid-19 mRNA shots, scientists have a far greater capacity to tailor shots to a virus's structure, putting a host of new vaccines on the horizon.

27 Oct 2023

Microbubble-based biomarker could improve NIR-PIT treatment for cancer

Researchers at Nagoya University in Japan and their collaborators have used a biomarker based on microbubbles to evaluate the success of near-infrared photoimmunotherapy (NIR-PIT) treatment.

26 Oct 2023

Study shows phages can promote mammalian cellular growth and survival

Bacteriophages, also called phages, are viruses that infect and kill bacteria, their natural hosts. But from a macromolecular viewpoint, phages can be viewed as nutritionally enriched packets of nucleotides wrapped in an amino acid shell.

26 Oct 2023

Dato-DXd improves progression-free survival in patients with metastatic non-squamous NSCLC

Treatment with datopotamab deruxtecan (Dato-DXd), a novel Trop-2 directed antibody-drug conjugate, was found to significantly improve progression-free survival in patients with metastatic non-small cell lung cancer, an improvement that was primarily driven by patients with non-squamous tumors.

26 Oct 2023

Study helps identify children at the highest risk of severe RSV infection

A new study helps to identify children who are at the highest risk of a severe respiratory syncytial virus (RSV) infection and who would thus benefit most from new RSV prevention measures.

26 Oct 2023

New Sartorius Digital Handbook brings the power of High-Throughput Screening (HTS) by cytometry to every scientist

Sartorius, an industry-leading innovator of advanced instruments for cell analysis has released its first Advanced Flow Cytometry Handbook as a comprehensive digital guide to assays and workflows on the iQue® Advanced High Throughput Flow Cytometry Platform.

From Sartorius 26 Oct 2023

Kids not the culprits: Low COVID-19 spread in U.S. child-care centers challenges closure norms

The study found that both children and care providers in U.S. child-care centers showed low rates of COVID-19 transmission, challenging the notion that these settings are high-risk environments for the virus. The results could have implications for revising guidelines on school and child-care center closures.

25 Oct 2023

How strep bacteria outsmart your immune system and why it matters for treatment

Researchers discover that Group A streptococcal infections alter immunoglobulin G (IgG) homeostasis to evade the immune system, affecting the transition from local to systemic infections. The study also raises concerns about the effectiveness of antibody-based therapies, as the bacteria's virulence factors can degrade therapeutic antibodies.

25 Oct 2023

NF-κB activation during COVID-19 and its impact on patients with hypertension

Researchers review the role of NF-κB activation in the replication of SARS-CoV-2 and the impact of COVID-19 medications on NF-κB activation.

25 Oct 2023

Study shows benefit of convalescent plasma in Covid-19 patients requiring artificial ventilation

In a study published in The New England Journal of Medicine, clinicians and researchers from the CHU of Liège and the University of Liège show that the administration of plasma taken from convalescent donors after infection with Sars-CoV-2 to patients suffering from acute respiratory distress syndrome requiring artificial mechanical ventilation significantly reduced mortality (10%).

25 Oct 2023

Omicron's edge: boosters pressure SARS-CoV-2 to adapt and evolve

The effects of vaccine booster doses on the adaptive evolution of the virus.

25 Oct 2023

BA.2.86 Omicron sub-variant shows high receptor affinity but moderate neutralization resistance

Study investigates the receptor affinity and antigenicity of the SARS-CoV-2 Omicron BA.2.86 variant, revealing that it does not show higher resistance to neutralization by human sera than other recent variants. Despite its high number of mutations and receptor affinity, the variant is slightly more sensitive to neutralization than the EG.5.1 variant, warranting continued surveillance.

24 Oct 2023

Community immunity: Steering the evolutionary course of SARS-CoV-2

Researchers in Germany have developed a comprehensive fitness model that forecasts the evolution of SARS-CoV-2 by integrating genetic, epidemiological, and immunological data. The study emphasizes the role of population immunity in shaping viral mutations and provides valuable insights into the emergence of new variants.

24 Oct 2023

Mapping the mysteries: Study reveals surprising hubs of human immune cells

Researchers in Israel comprehensively mapped the distribution and mass of primary immune cells across human tissues. This groundbreaking study, using advanced biotechnological methods, provides insights into the immune system's cellular network, challenging existing notions and emphasizing the bone marrow, lymph nodes, and spleen as primary immune cell reservoirs.

24 Oct 2023

Antibody News and Research

Further Reading

New antibody may offer effective drug treatment for breast cancer

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

Redefining the battle against Alzheimer's with tau-focused treatments

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

A new era of vaccines leaves old questions about prices unanswered

Microbubble-based biomarker could improve NIR-PIT treatment for cancer

Study shows phages can promote mammalian cellular growth and survival

Dato-DXd improves progression-free survival in patients with metastatic non-squamous NSCLC

Study helps identify children at the highest risk of severe RSV infection

New Sartorius Digital Handbook brings the power of High-Throughput Screening (HTS) by cytometry to every scientist

Kids not the culprits: Low COVID-19 spread in U.S. child-care centers challenges closure norms

How strep bacteria outsmart your immune system and why it matters for treatment

NF-κB activation during COVID-19 and its impact on patients with hypertension

Study shows benefit of convalescent plasma in Covid-19 patients requiring artificial ventilation

Omicron's edge: boosters pressure SARS-CoV-2 to adapt and evolve

BA.2.86 Omicron sub-variant shows high receptor affinity but moderate neutralization resistance

Community immunity: Steering the evolutionary course of SARS-CoV-2

Mapping the mysteries: Study reveals surprising hubs of human immune cells

Monoclonal Antibody Manufacturing Trends eBook eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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