Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Immunoglobulins might be promising treatment for Alzheimer's disease

Intravenous immunoglobulin might offer a promising treatment for Alzheimer's disease, suggests preliminary research in the Journal of Neurology Neurosurgery and Psychiatry.

15 Sep 2004

New biological principle and therapeutic goal for cancer treatment

Pioneering research on leukaemia cells can have identified their vulnerable spot. This new knowledge can now be used to produce more effective medicines.

14 Sep 2004

Researchers have discovered a possible way to distinguish lethal from localized prostate cancers

If future studies show their test -- measuring the level of activity of a signaling pathway called Hedgehog -- can predict which prostate cancers will spread, the results could revolutionize decision making processes for prostate cancer patients, the researchers say.

13 Sep 2004

Transthyretin discovery may halt progression of Alzheimer's

In a finding that may cause a dramatic shift in the way scientists and researchers search for a therapy for Alzheimer's disease, a team of researchers led by Jeff Johnson, an associate professor at the School of Pharmacy, has discovered that increased expression of a protein called transthyretin in the brain appears to halt the progression of the disease.

10 Sep 2004

Researchers uncover how HIV causes abnormalities in antibody-producing cells

HIV wreaks much of its damage by targeting the “orchestra conductor” of the immune system, a key class of T cells—CD4+ T cells—whose destructive relationship with HIV has been well-studied by AIDS researchers.

8 Sep 2004

Long-term outcomes for liver transplantation due to hepatitis C

A new study on liver transplants necessitated by the hepatitis C virus (the most common indication for this type of transplant) found that long-term outcomes are similar to patients receiving transplants due to other diseases.

8 Sep 2004

Phase I clinical trial of new drug for severe asthma

Cambridge Antibody Technology today announced that it is starting a Phase I clinical trial of CAT-354, a human anti-IL-13 monoclonal antibody, which is a potential treatment for severe asthma, following recent approval from the Medicines and Healthcare products Regulatory Agency (MHRA).

8 Sep 2004

MorphoSys obtains license on human cell line technology for use in its antibody research

MorphoSys has announced today a non-exclusive license agreement with Dutch biotechnology company Crucell and DSM Biologics.

8 Sep 2004

Sinovac completes dosing in phase 1 human clinical testing of SARS vaccine

Sinovac Biotech Ltd. has announced that all 36 subjects of the Phase I human clinical trial for its inactivated SARS vaccine have now been vaccinated with two doses of either SARS vaccine or placebo.

7 Sep 2004

Stopping bacteria from talking to each other could help prevent serious infections

Stopping bacteria from talking to each other could help prevent serious infections say scientists from Aberdeen, in new research presented Monday at the Society for General Microbiology’s 155th Meeting at Trinity College Dublin.

7 Sep 2004

Hair growing stem cells may one day provide treatments for human hair conditions

Researchers at the Howard Hughes Medical Institute at The Rockefeller University have isolated stem cells from the skin of a mouse, and showed, for the first time, that an individual stem cell can renew itself in the laboratory and then be used in grafts to produce skin, hair and oil glands.

5 Sep 2004

Chiron acquires a variant Creutzfeldt-Jakob disease research company

Chiron Corporation has announced that it had acquired Prion Solutions Inc., a privately held company based in La Jolla, Calif., focused on research into variant Creutzfeldt-Jakob disease (vCJD) and other prion-related diseases. Financial terms of the acquisition were not disclosed.

1 Sep 2004

Major trends in AIDS research that the different research teams throughout the world are pursuing

The science will be presented during the conference which is taking place in Lausanne until September 1, 2004. The advances in fundamental research, notably through a better understanding of the complex processes of immune defence, HIV and the functioning of vaccines, promote the genesis and development of new vaccine candidates.

30 Aug 2004

Call for increased political and financial commitment to the development of preventive and therapeutic AIDS vaccines

At the opening ceremony of the Lausanne, Switzerland, AIDS VACCINE '04 conference, leaders in the field of AIDS vaccine research called for increased political and financial commitment to facilitate the development of preventive and therapeutic AIDS vaccines as a public health imperative in fighting HIV/AIDS.

30 Aug 2004

More women are surviving advanced breast cancer

Writing in the Journal of Clinical Oncology, (Vol. 22, No. 16: 3302-3308), doctors from 3 French hospitals reported on 724 women whose first diagnosis was breast cancer that had spread to other parts of the body (stage 4). It is rare for women to be diagnosed with such late stage disease.

27 Aug 2004

Phase 1 clinical trial of new anticancer drug from Human Genome Sciences

Human Genome Sciences has begun dosing patients in a Phase 1 clinical trial of HGS-TR2J, a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies.

25 Aug 2004

Regular exercise boosts immune system in older men

As it turns out, judging by the reaction strength of their immune system to an unknown, but harmless, protein antigen, it’s possible for men over 70 to mount an immune response similar to that produced by much younger men -- if they get regular moderate physical activity of about six hours a week.

25 Aug 2004

Powerful new cancer-fighting property of Herceptin

For many patients with advanced breast cancer, the cancer drug Herceptin (trastuzumab) has offered new hope when traditional cancer drugs failed to work, shrinking tumors and sending some patients into remission.

23 Aug 2004

Researchers find how cancers, particularly lymphomas, develop and might be prevented

Researchers at Children's Hospital Boston have begun unraveling the mystery of how B lymphocytes - key infection-fighting cells in the body - are able to create many different kinds of specialized antibodies through selective gene mutations, while being protected from random mutations that could give rise to cancers.

23 Aug 2004

Exposure to simian virus 40 (SV40) is not associated with cancer in humans

Two upcoming studies by scientists at the National Cancer Institute (NCI), provide further evidence that exposure to simian virus 40 (SV40) is not associated with cancer in humans.

23 Aug 2004