Anticoagulant News and Research

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Pancreatitis drug Nafamostat shows promise for coronavirus

With the increasing number of infections across the globe, scientists have resorted to studying existing drugs in the hope of discovering a cure for the coronavirus disease (COVID-19). A team of researchers has found that an existing drug, Nafamostat or Fusan, a drug used to treat acute pancreatitis, may effectively block the process used by the novel coronavirus to spread and cause illness.

1 Apr 2020

CVIA publishes new issue that brings key research papers from top cardiologists

The journal Cardiovascular Innovations and Applications (CVIA) has just published a new issue, Volume 4 Issue 3 with an invitation to join the International Brugada Electrocardiographic Indices Registry.

1 Apr 2020

Direct oral anticoagulant more effective in lowering risk of VTE after common orthopedic surgeries

The direct oral anticoagulant rivaroxaban dramatically cut the likelihood of serious venous thromboembolism (VTE) in people recovering from lower limb orthopedic surgery requiring immobilization in comparison with enoxaparin, another anticoagulant agent, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Oral apixaban as effective as dalteparin for treating blood clots in people with cancer

For people with cancer, the oral blood thinner apixaban is at least as effective as dalteparin, a low molecular weight heparin given by injection, in preventing a repeat venous thromboembolism (VTE), or blood clot, with no excess in major bleeding events, according to Phase 3 trial results presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Adding antiplatelet therapy to oral anticoagulants raises risk for TAVR patients with atrial fibrillation

Patients with atrial fibrillation who took oral anticoagulants alone after undergoing transcatheter aortic valve replacement had a lower rate of bleeding complications without an increased risk of clotting-related complications compared to patients who took antiplatelet medication in addition to oral anticoagulants, in a trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

29 Mar 2020

How cannabis interacts with medications

A new practice guideline published in the journal CMAJ in February 2020 describes five types of drug interactions possible with the use of cannabis. Cannabis is a plant-derived drug containing the psychoactive ingredient delta-9-tetrahydrocannabinol (THC) and non-psychoactive cannabidiol (CBD). These cannabinoids are broken down by the liver enzymes cytochrome P450 C(YP)34A, and CYP2CC9.

2 Mar 2020

Study finds racial, ethnic disparities in stroke prevention among patients undergoing dialysis

In a study of patients with kidney failure and atrial fibrillation, racial/ethnic minorities experienced higher rates of stroke compared with non-Hispanic White patients, and they were less likely to fill prescriptions of stroke-preventive medications.

20 Feb 2020

Alarming link between marijuana and increased heart risk

Marijuana use is rising steadily across the US as more and more states enact laws making it a legal recreational and medicinal agent. However, a new study underlines the fact that this is, in fact, playing with an unknown substance, which may cause serious bodily harm. The review article, published in the Journal of the American College of Cardiology, shows that more than 2 million adults who currently have heart or vascular disease gave a history of being currently on marijuana products, or having used them in the past.

20 Jan 2020

New evidence-based clinical practice guideline for nosebleed published

The American Academy of Otolaryngology-Head and Neck Surgery Foundation published the Clinical Practice Guideline: Nosebleed (Epistaxis) today in Otolaryngology-Head and Neck Surgery.

7 Jan 2020

Researchers show new potential path to improve bone-repair procedures

Researchers are moving closer to a new approach for improving spinal fusion procedures and repairing broken or defective bones that avoids an over-production of bone that commonly occurs in current treatments.

3 Jan 2020

First reported occurrence and treatment of venous thrombosis during spaceflight

Serena Auñón-Chancellor, M.D., M.P.H., Clinical Associate Professor of Medicine at LSU Health New Orleans School of Medicine's branch campus in Baton Rouge, is the lead author of a paper describing a previously unrecognized risk of spaceflight discovered during a study of astronauts involved in long-duration missions.

2 Jan 2020

Inhibition of a single enzyme may reduce heparin-induced thrombocytopenia

Heparin is widely used as an anticoagulant, but evokes in some patients a potentially life-threatening condition called HIT. Clinical scientists at Ludwig-Maximilians-Universitaet in Munich have now shown that inhibition of a single enzyme may markedly reduce this risk.

21 Dec 2019

Researchers develop spray gel for frostbite injuries

Mountaineers and winter sports enthusiasts know the dangers of frostbite -- the tissue damage that can occur when extremities, such as the nose, ears, fingers and toes, are exposed to very cold temperatures. However, it can be difficult to get treated quickly in remote, snowbound areas.

11 Dec 2019

LUNAC-led drug discovery project receives funding under Innovate UK’s Biomedical Catalyst program

LUNAC Therapeutics, a UK based drug discovery company focused on the identification and development of advanced anticoagulants with minimal bleeding risk, today announced that, along with the Medicines Discovery Catapult and the University of Leeds, it has been awarded £3.14M funding under Innovate UK’s Biomedical Catalyst program.

4 Dec 2019

Researchers find new way to interpret blood tests to diagnose pulmonary embolism

A study led by Hamilton researchers has found a new way to interpret blood test results in patients who are investigated for blood clots in their lungs, a condition known as pulmonary embolism.

27 Nov 2019

Geospatial model helps compare costs of different anticoagulant therapies

Appropriately selected anticoagulation therapy can help to reduce the medical costs of patients suffering from atrial fibrillation. A new study from the University of Eastern Finland shows that direct oral anticoagulants can be a more cost-effective alternative than traditional warfarin therapy when the patient's place of residence is taken into consideration.

27 Nov 2019

Miniscule robots like "Magic School Bus" could clear blood clots

Pulmonary embolism is a condition where a clot forms and blocks the arteries of the lungs and this restricts the blood flow to the lungs and lowers the amount of oxygen reaching the different organs. Statistics from the National Institutes of Health show that pulmonary embolism leads to nearly 200,000 to 300,000 deaths in the United States annually putting it at number three in cardiovascular diseases right after heart attack and stroke.

19 Nov 2019

LUNAC announces spin out with £2.65 million funding to develop advanced anticoagulants

LUNAC Therapeutics today announced it has spun out of the University of Leeds with £2.65M funding in the first close of a Series A financing round.

15 Nov 2019

Clinical benefit of anticoagulants for atrial fibrillation decreases with age, shows study

The net clinical benefit of anticoagulants for atrial fibrillation (AF) -- one of the most important causes of irregular heartbeats and a leading cause of stroke -- decreases with age, as the risk of death from other factors diminishes their benefit in older patients, according to a study led by researchers at UC San Francisco.

11 Nov 2019

Researchers investigate whether aspirin can decrease rate of intracranial aneurysm growth

Researchers conducted a database search to investigate whether aspirin can aid in the prevention of intracranial aneurysm rupture by hindering aneurysm growth. The researchers identified 146 patients harboring multiple intracranial aneurysms, five millimeters or less in diameter, that had been observed for at least five years.

29 Oct 2019