Anticonvulsants News and Research

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Scientists explore potential new ways to prevent and treat optic nerve hypoplasia

As the number of children born with a vision-impairing condition known as optic nerve hypoplasia (ONH) increases, scientists with the Fralin Biomedical Research Institute at VTC are investigating potential ways to prevent and treat the disease.

30 Jan 2023

Neurons in a bow-shaped brain region become hyperactive after chronic stress exposure

It's clear that chronic stress can impact our behavior, leading to problems like depression, reduced interest in things that previously brought us pleasure, even PTSD.

24 Jan 2023

Buprenorphine-involved overdose deaths did not increase after implementation of prescribing flexibilities

The proportion of opioid overdose deaths involving buprenorphine, a medication used to treat opioid use disorder, did not increase in the months after prescribing flexibilities were put in place during the COVID-19 pandemic, according to a new study.

20 Jan 2023

Supplementary folic acid associated with higher risk of COVID-19 diagnosis and mortality

In a recent study published in the journal BMJ Open, researchers investigated the impact of folic acid supplements and methotrexate, in combination or individually, on disease severity and mortality in coronavirus disease 2019 (COVID-19) cases.

8 Sep 2022

Experts use tools from artificial intelligence to rapidly identify substances that cause overdose deaths

An automated process based on computer algorithms that can read text from medical examiners' death certificates can substantially speed up data collection of overdose deaths – which in turn can ensure a more rapid public health response time than the system currently used, new UCLA research finds.

9 Aug 2022

How common is pediatric cannabis use and what are the risks?

New research evaluated the recent usage of marijuana and its derivative products, their effects and clinical manifestations, perceptions, pharmaceutics, epidemiological studies, and the long-term ramifications in pediatric populations.

12 Jul 2022

Association of neuronal and non-neuronal GABA with neuropsychiatric illness in COVID-19 patients

A new study published in the journal Reports focused on the hijacking of the pancreatic, endothelial, and gut GABA by SARS-CoV-2 and its associated pathology along with interventions.

10 Jun 2022

Medical cannabis use shown to improve cancer-related symptoms in new study

Researchers describe the effectiveness and safety of medical cannabis use for treating cancer-related symptoms.

30 May 2022

Study shows link between psychotropic medication use and post-Covid dementia

Recent studies have highlighted the connection between coronavirus disease 2019 (COVID-19) infection and the development of dementia.

23 Mar 2022

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

In a recent study posted to the medRxiv* preprint server, researchers evaluated if folic acid or methotrexate use impacts the risk of coronavirus disease 2019 (COVID-19) diagnosis or associated mortality in the United Kingdom (UK).

15 Feb 2022

CRISPRa identifies potassium channels as neuronal entry factors and druggable targets for SARS-CoV-2

New research led by Le Cong of Stanford University School of Medicine in California indicates that the KCNA6 potassium channel may help with viral entry and promote infection. In addition, KCNA6 is highly expressed in OLIG2+ neuronal cells, which has been shown to be suspectable to SARS-CoV-2 in the olfactory neuroepithelium. This area appears to contribute to loss of smell commonly observed during infection.

6 Jul 2021

Study: 94% of older adults prescribed fall-risk-increasing drugs

Nearly every older adult was prescribed a prescription drug that increased their risk of falling in 2017, according to new University at Buffalo research.

16 Mar 2021

High levels of folic acid during pregnancy could harm brain development of embryos

A UC Davis MIND Institute study of pregnant mice found that high amounts of folic acid during pregnancy harmed the brain development of embryos. Researchers say the findings indicate that more investigation is needed about the best recommended dosage for pregnant women.

5 Oct 2020

Analysis reveals cocktail of pharmaceuticals in the waters of Bangladesh

In spring of 2019, researchers set out to investigate what chemicals could be found in the waters of Bangladesh.

20 Apr 2020

Common drug for nerve pain could help restore upper limb function after spinal cord injury

Long-term treatment with gabapentin, a commonly prescribed drug for nerve pain, could help restore upper limb function after a spinal cord injury, new research in mice suggests.

3 Dec 2019

Johns Hopkins researchers estimate real-world prevalence of prurigo nodularis

Johns Hopkins researchers report that prurigo nodularis, a skin disease characterized by severely itchy, firm bumps on the skin, may be associated with other inflammatory skin disorders as well as systemic and mental health disorders.

From Johns Hopkins Medicine 26 Aug 2019

Molecular action that enables cilantro to effectively delay certain seizures uncovered

Herbs, including cilantro, have a long history of use as folk medicine anticonvulsants. Until now, many of the underlying mechanisms of how the herbs worked remained unknown.

23 Jul 2019

Compounded pain relief creams not effective finds study

A new study has shown that pain relief creams are no better than dummy or placebo creams when it comes to relieving pain.

6 Feb 2019

Anticonvulsants found to be ineffective for low back pain and can have adverse effects

Anticonvulsant drugs are increasingly being used to treat low back pain, but a new study in CMAJ finds they are ineffective and can have adverse effects.

3 Jul 2018

$Chronic use of opioids related to increased risk of fracture nonunion$

Chronic use of opioids related to increased risk of fracture nonunion

Dr. Robert Zura, Professor and Chair of Orthopaedic Surgery at LSU Health New Orleans School of Medicine, was part of a research team reporting that not only may opioid use increase the risk of bone fractures, but opioids may also impair healing.

18 Jun 2018