Antifungal News and Research

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Antifungals and probiotics could play critical role in potential new therapeutic approaches for IBD

Scientists have determined that fungus may play a key role in chronic intestinal inflammation disorders. They found that patients with Crohn's disease tend to have much higher levels of the fungus Candida tropicalis compared to their healthy family members.

5 Oct 2017

Columbia University receives $9.6 million NIH grant for ME/CFS research center

The National Institutes of Health has awarded a five-year $9.6 million grant to the Center for Infection and Immunity at Columbia University's Mailman School of Public Health to create the Center for Solutions for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (CfS for ME/CFS), an inter-disciplinary, inter-institutional research group dedicated to understanding the biology of the disease in order to develop effective means to diagnose, treat and prevent it.

27 Sep 2017

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Fungal infections represent an increasing health crisis, especially for immune-deficient patients. American scientists now report in the journal Angewandte Chemie that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action.

21 Sep 2017

New collaboration could lead to novel drugs that address unmet medical needs

Southern Research and the University of Tennessee Health Science Center have formed a partnership to advance promising research that could lead to new drugs that address unmet medical needs.

20 Sep 2017

Benefits of charcoal-based dentifrices for oral hygiene still unproven

The growing visibility of charcoal and charcoal-based dentifrices, including many that are offered for sale on the Internet, raises questions about the re-emerging practice of brushing teeth with products containing charcoal.

24 Aug 2017

Multi-drug resistant fungi found in UK hospitals - alarms health officials

Latest reports have confirmed that over 200 patients in England have been infected with a drug-resistant fungus called Candida auris that was first detected in Japan. High alerts have been put in place to look out for further infections and prevent spread.

15 Aug 2017

Tips to follow when you notice signs or symptoms of ringworm

What do athlete's foot, jock itch, and barber's itch all have in common? They are all cases of ringworm, say dermatologists from the American Academy of Dermatology.

8 Aug 2017

Vanderbilt researchers unravel how bacterial toxin prevents DNA replication

One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA.

2 Aug 2017

GW researchers find nitric oxide-releasing nanoparticles as viable treatment for fungal skin infections

George Washington University researchers have found that topically applied nitric oxide-releasing nanoparticles (NO-np) are a viable treatment for deep fungal infections of the skin caused by dermatophytes, for which the current standard of care is treatment with systemic antifungals.

31 Jul 2017

Researchers question use of fungicides on imported flowers, bulbs that induce antifungal drug resistance

Researchers in Manchester are questioning the legal use of certain fungicides used on imported flowers and bulbs following evidence that they induce resistance to the drugs used to treat patients with Aspergillus fumigatus, a virulent of fungal disease.

From The University of Manchester 27 Jun 2017

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

A microscopic fungus called Candida tropicalis triggered gut inflammation and exacerbated symptoms of Crohn's disease, in a recent study conducted at Case Western Reserve University School of Medicine.

22 Jun 2017

Scientists discover new approach for antifungal drug treatments

Each year, invasive fungal infections sicken an estimated 2 million people worldwide and kill nearly 800,000 - but a team of international scientists have discovered a new approach for antifungal drug treatments.

15 Jun 2017

Researchers link intestinal fungi to increased risk of death in patients with alcoholic liver disease

Liver cirrhosis is the 12th leading cause of mortality worldwide and approximately half of those deaths are due to alcohol abuse.

23 May 2017

Despite availability of life-saving medicaiton, annual deaths due to fungal meningitis are still over 180,000

International HIV experts have reported approximately 250,000 fungal meningitis cases annually, in the AIDS report, sub-Saharan Africa contributing 73% of cases. Cryptococcus fungus causes fungal meningitis and usually affects individuals who are above 35 years old, affecting the tissues covering the brain and the spinal cord

8 May 2017

Brown University researchers develop new multi-reaction catalyst

Brown University researchers have developed a new composite catalyst that can perform four separate chemical reactions in sequential order and in one container to produce compounds useful in making a wide range of pharmaceutical products.

25 Apr 2017

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

An antimicrobial protein caused a dramatic reduction in the creamy white lesions associated with oral thrush in a preclinical study, report microbiologists with McGovern Medical School at The University of Texas Health Science Center at Houston.

11 Apr 2017

Dermatologist recommends simple tips to prevent toenail fungus

Although fungal nail infections are usually painless, the condition can be unsightly. If you get nail fungus - more common on the toenails than the fingernails - your symptoms could include yellow or brown nails, or nails that lift up from the nail bed or split or crumble.

14 Mar 2017