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How cannabis interacts with medications

A new practice guideline published in the journal CMAJ in February 2020 describes five types of drug interactions possible with the use of cannabis. Cannabis is a plant-derived drug containing the psychoactive ingredient delta-9-tetrahydrocannabinol (THC) and non-psychoactive cannabidiol (CBD). These cannabinoids are broken down by the liver enzymes cytochrome P450 C(YP)34A, and CYP2CC9.

2 Mar 2020

Five things to know about drug interactions with cannabinoids

A practice article provides 5 things to know on how drugs can interact with cannabinoids in CMAJ.

2 Mar 2020

Study finds significant increase in skin allergy to 'bee glue'

Skin allergy to an ingredient found in many natural skin products has more than doubled since 2007, according to a study in the British Journal of Dermatology.

28 Feb 2020

Metal complexes could hold the key to next generation of antibiotics

Compounds containing metals could hold the key to the next generation of antibiotics to combat the growing threat of global antibiotic resistance.

27 Feb 2020

Essential oil components could meet the criteria set for drug candidates

A research team at the VIB-KU Leuven Center for Microbiology and the KU Leuven Department of Biology showed that, contrary to generally held belief, most components of essential oils could meet the criteria set for drug candidates.

23 Feb 2020

Swansea University drug resistance research highlighted in two prestigious journals

Swansea University research into the threat posed by antifungal drug resistance has been highlighted in two prestigious international journals.

14 Feb 2020

Acid reflux drug may be a promising therapy to reduce preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of the drugs in mice.

13 Feb 2020

Scientists discover potential drug compounds that target common type of liver cancer

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)'s Genome Institute of Singapore have discovered four potential drug compounds that target hepatocellular carcinoma, the most common type of liver cancer.

30 Dec 2019

Valley fever cases climb in California’s Central Valley — and beyond

Valley fever cases are on the rise in California and across the arid Southwest, and scientists point to climate change and population shifts as possible reasons.

17 Dec 2019

Yeasts derived from food can reduce multi-drug resistant fungal infections

A study by researchers in the United States and India has shown that probiotic yeasts derived from food are able to reduce the virulence of, and even prevent infections by, several types of fungi that are responsible for life-threatening infections in hospitalized and immune-compromised individuals, including the multi-drug resistant Candida auris, which was recently listed as an urgent threat by the U.S. Centers for Disease Control in its 2019 Antibiotic Resistance Threats report.

10 Dec 2019

Yale study highlights the need to develop effective, less toxic approaches to treat AML patients

A new study by Yale Cancer Center researchers shows understanding treatment patterns for patients with acute myeloid leukemia is vital to develop strategies to improve outcomes.

9 Dec 2019

Common first-line treatment for cryptococcal meningitis in being compromised by drug resistance

A common first-line treatment approach for cryptococcal meningitis in low-income countries is being compromised by the emergence of drug resistance, new University of Liverpool research warns.

8 Dec 2019

Common treatment for cryptococcal meningitis compromised by emergence of drug resistance

A common first-line treatment approach for cryptococcal meningitis in low-income countries is being compromised by the emergence of drug resistance, new University of Liverpool research warns.

6 Dec 2019

Failure to ensure environmental management of pharmaceuticals can lead to adverse outcomes

Poor sanitation leads to untreated wastewater entering river systems in many countries where industrialisation and urbanisation is not supported by appropriate infrastructure.

3 Dec 2019

Medicinal plants: from genes to drugs

We eat plants, wear their products, burn them for fuel, and use them to build our houses. Plants are the very basis of the food chain on earth. They are also the source of oxygen in the atmosphere, and a treasure house containing a host of compounds that have biological effects on the body. Some of these chemicals are produced as self-defence, to guard against pests and diseases.

27 Nov 2019

Study on sea sponge opens up possibilities to create new antitumor drugs

Chemists from Far Eastern Federal University's School of Natural Sciences developed a new method to synthesize biologically active derivatives of fascaplysin -- cytotoxic pigment of a sea sponge. For the first time, they got a sufficient amount of 3-bromofascaplysin and 3,10-dibromofascaplysin, which were known before but were not available for study.

14 Nov 2019

Kazan University showcases innovative antiseptic in Vienna

The event was co-organized by the Ministry of Industry and Trade of Russia, Skolkovo, Russian Venture Company, ChemRar, RDI Group, Vienna Business Agency, and others.

30 Oct 2019

Study uses baker's yeast to show how genes interact to influence a surprising cellular outcome

Most diseases are complex--caused by faults in multiple genes--but studying how combinations of different genetic variants affect cellular traits is challenging.

23 Oct 2019

Researchers create new material with antifungal and antitumor properties

A new material with antifungal and antitumor properties has been developed by researchers at the Center for Development of Functional Materials (CDMF), one of the Research, Innovation and Dissemination Centers (RIDCs) supported by São Paulo Research Foundation - FAPESP.

3 Oct 2019

Certain fungi increase pancreatic cancer risk, study finds

Certain fungi move from the gut to the pancreas, expand their population more than a thousand-fold, and encourage pancreatic cancer growth, a new study finds.

2 Oct 2019