Antioxidant News and Research

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Antioxidants are substances that protect cells from the damage caused by free radicals (unstable molecules made by the process of oxidation during normal metabolism). Free radicals may play a part in cancer, heart disease, stroke, and other diseases of aging. Antioxidants include beta-carotene, lycopene, vitamins A, C, and E, and other natural and manufactured substances.

New trial for treatment of liver disease

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network is launching its first two clinical trials for the study of NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol.

3 Apr 2005

Cranberry juice may help protect against heart disease

Protection against a wide variety of diseases is among the many benefits of a diet high in whole fruits and vegetables. Cranberries over the years have been identified with preventing or ameliorating urinary tract infections and playing a positive role gum disease, ulcers and even cancer.

3 Apr 2005

Children with autism have a severely abnormal metabolic profile

Chronic biochemical imbalance is often a primary factor in the development of many complex diseases but a possible metabolic basis for autism has not been well explored. Now Arkansas Children's Hospital Research Institute researchers report for the first time that children with autism have a severely abnormal metabolic profile indicating increased vulnerability to oxidative stress.

3 Apr 2005

Hemodialysis causes antioxidant loss leading to long-term complications

An article published in Hemodialysis International discusses the role of oxidative stress (OS) in dialysis patients, an imbalance which can result in long-term health problems. Potential therapeutic options to restore balance in patients are also reviewed.

30 Mar 2005

Pomegranate juice helps keep fatty deposits from collecting on artery walls

A study in the current issue of the Proceedings of the National Academy of Sciences, by Italian and American scientists reports that pomegranate juice helped keep fatty deposits from collecting on artery walls in mice, and kept human heart cells healthier. The mice were specially bred to have high cholesterol and on human heart cells in culture.

22 Mar 2005

Compound found in broccoli is a powerful disease fighter

More than 300 scientific studies point to an antioxidant found in broccoli sprouts, sulforaphane glucosinolate (SGS), as a factor in preventing multiple diseases, including several types of cancer, high blood pressure, macular degeneration and stomach ulcers.

21 Mar 2005

Questions about validity of HOPE TOO vitamin E study

A study published in the March 16 issue of Journal of the American Medical Association (JAMA) suggesting that a "daily-dose" of vitamin E (400 international units) among high-risk (chronically ill) cardiovascular patient populations is associated with a greater risk of heart failure is being challenged by leading health researchers around the country who claim the study lacks the adequate research and controlled sampling audience to justify this conclusion.

16 Mar 2005

More research on Vitamin E surprises scientists

50 years of research into the supposed benefits of taking vitamin E has extolled its antioxidant potential to offer a variety of potential health benefits, including reducing the risk of Alzheimer's, cancer and heart disease.

15 Mar 2005

Beneficial effects of Alpha-Linolenic acid in walnuts

The recently-announced USDA dietary guidelines stress the need for consumers to be more aware of the benefits of polyunsaturated essential omega-3 fatty acids in order to achieve a healthy diet. Many people look to fish, such as salmon, for omega-3s, but plant sources such as walnuts are also specifically noted in the USDA recommendations.

15 Mar 2005

Selenium, vitamin E and the tomato nutrient lycopene have been shown to reduce prostate cancer

Greater levels of selenium, vitamin E and the tomato nutrient lycopene have been shown to reduce prostate cancer in one out of every four Caucasian males - those who inherit a specific genetic variation that's particularly sensitive to oxidative stress.

15 Mar 2005

Gene identified that confers susceptibility to age-related macular degeneration

By combining the tools of high-throughput biology and statistical genetics, scientists at Rockefeller University, Yale University School of Public Health and the National Eye Institute have identified a gene that confers susceptibility to age-related macular degeneration (AMD), the most common cause of vision loss in the United Sates for those over 60.

14 Mar 2005

Protein circulating in the blood delivers selenium to germ cells, enabling normal development of sperm

A paper to be published in the journal Biology of Reproduction offers evidence that a protein circulating in the blood of mammals delivers the dietary micronutrient selenium to germ cells, enabling these cells to develop into normal sperm.

7 Mar 2005

An apple a day keeps breast cancer away

An apple a day can help keep breast cancer away, according to a study in rats by food scientists at Cornell University.

1 Mar 2005

Scientific experts discuss the benefits and safety of vitamin E

Scientific experts in pharmacology, toxicology and nutrition gathered at the University of Southern California (USC) on February 26 for a forum to discuss the benefits and safety of vitamin E.

1 Mar 2005

Researchers have identified a protein called HIF-2a, which is important in retina formation

Hoping to prevent blindness in premature babies, UT Southwestern Medical Center researchers have identified a protein that responds to oxygen levels in cells and tissues and also affects the developing eye.

22 Feb 2005

Green tea protects livers

A new study investigating the effects of the major flavonoid component of green tea on hepatic steatosis (fatty liver) found that it significantly protected livers that suffered ischemia/reperfusion (I/R) injury in mice. I/R injury, which is caused by decreased blood flow, can lead to complications after liver transplantation.

20 Feb 2005

How polychlorinated biphenyls open brain cells to Parkinson's assault

University of Rochester scientists investigating the link between PCBs, pesticides and Parkinson's disease demonstrated new and intricate reactions that occur in certain brain cells, making them more vulnerable to injury after exposures.

9 Feb 2005

High consumption of dairy products and fruits and vegetables may lower the risk of disability

There may be more reason than ever to drink your milk and eat your fruits and vegetables. A Wake Forest University Baptist Medical Center researcher and colleagues reported today that high consumption of dairy products and fruits and vegetables may lower the risk of disability, especially among black women.

7 Feb 2005

You'll live longer if you drink wine instead of beer

A recent article in the Journal of Thrombosis and Haemostasis determined that drinkers of wine benefit from its cardio-protective effects, more so than those who drink beer or other spirits, and may also live longer.

31 Jan 2005

Antioxidants do not prolong the survival of patients with amyotrophic lateral sclerosis, or Lou Gehrig’s disease

A review of recent studies suggests that antioxidant supplements, including vitamin E and selenium, do not prolong the survival of patients with amyotrophic lateral sclerosis, or Lou Gehrig’s disease.

24 Jan 2005

Antioxidant News and Research

Further Reading

New trial for treatment of liver disease

Cranberry juice may help protect against heart disease

Children with autism have a severely abnormal metabolic profile

Hemodialysis causes antioxidant loss leading to long-term complications

Pomegranate juice helps keep fatty deposits from collecting on artery walls

Compound found in broccoli is a powerful disease fighter

Questions about validity of HOPE TOO vitamin E study

More research on Vitamin E surprises scientists

Beneficial effects of Alpha-Linolenic acid in walnuts

Selenium, vitamin E and the tomato nutrient lycopene have been shown to reduce prostate cancer

Gene identified that confers susceptibility to age-related macular degeneration

Protein circulating in the blood delivers selenium to germ cells, enabling normal development of sperm

An apple a day keeps breast cancer away

Scientific experts discuss the benefits and safety of vitamin E

Researchers have identified a protein called HIF-2a, which is important in retina formation

Green tea protects livers

How polychlorinated biphenyls open brain cells to Parkinson's assault

High consumption of dairy products and fruits and vegetables may lower the risk of disability

You'll live longer if you drink wine instead of beer

Antioxidants do not prolong the survival of patients with amyotrophic lateral sclerosis, or Lou Gehrig’s disease

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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