Antipsychotic News and Research

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Antipsychotics are medicines used to treat the symptoms of mental disorders such as schizophrenia, depression, bipolar disorder (sometimes called manic-depressive illness), anxiety disorders, and attention deficit-hyperactivity disorder (ADHD). Sometimes medications are used with other treatments such as psychotherapy.

Clozapine improves outcomes in treatment-resistant schizophrenia

The Psychiatry and Mental Health research group at the Germans Trias i Pujol Research Institute (IGTP), together with the ETEP (Study and Treatment of Psychotic Episodes) group at Hospital del Mar, has published a study in the Spanish Journal of Psychiatry and Mental Health that analyzes the use of clozapine in patients with treatment-resistant schizophrenia in the first two years after the first psychotic episode (FEP).

12 Jul 2024

Study reveals link between the use of antipsychotics in dementia and socioeconomic status

A study led by the Economic Evaluation of Chronic Diseases group of Biogipuzkoa Health Research Institute has revealed the relationship between the use of antipsychotics in dementia and socioeconomic status.

2 Jul 2024

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Schizophrenia is a complicated mental health disorder accompanied by wide range of symptoms such as hallucinations, impaired cognitive ability, and disorganized speech or behavior.

27 Jun 2024

Quality Improvement Program for Missouri saves millions and enhances elder care

A researcher at the University of Missouri has developed a program that improves the quality of care and reduces avoidable hospitalizations in nursing homes -; saving Missouri nursing homes and Medicare millions of dollars and allowing Missouri nursing homes to invest more in retaining their most skilled staff members.

24 Jun 2024

Research points to a potential approach to mitigating diabetes risk from antipsychotic medications

New University of Pittsburgh research points to a potential approach to reducing the risk of diabetes associated with widely prescribed antipsychotic medications.

13 Jun 2024

Common drugs linked to reduced risk of bleeding stroke from brain aneurysm

A new study suggests that people who take a few common drugs may have a decreased risk of having a bleeding stroke due to a ruptured brain aneurysm.

5 Jun 2024

Psychoactive drugs are having a moment. The FDA will soon weigh in.

Lori Tipton is among the growing number of people who say that MDMA, also known as ecstasy, saved their lives.

29 May 2024

Novel coating in antipsychotics mitigates unwanted weight gain and boosts serotonin levels

Thousands of Australians struggle with serious mental health conditions. But when the recommended treatment involves antipsychotic medications, the side effects are excess kilos, which only adds weight to an already complex diagnosis.

28 May 2024

New help for dealing with aggression in people with dementia

Caring for older adults with dementia is stressful, especially when they become physically or verbally aggressive, wander away from home, develop paranoia or hallucinations, engage in inappropriate or repetitive behaviors, or refuse to let caregivers help them.

28 May 2024

Medicare warning letters effectively cut antipsychotic prescribing for dementia patients

Warning letters from Medicare can safely cut prescribing of a powerful but risky antipsychotic, according to a new study at Columbia University Mailman School of Public Health.

25 Apr 2024

Risks of antipsychotic use in dementia extend beyond previous alerts, study shows

Antipsychotic use in people with dementia is associated with higher risks of a wide range of serious health outcomes compared with non-use, according to a new study from a collaboration across the Universities of Manchester, Nottingham, Edinburgh and Dundee.

23 Apr 2024

Study shows antipsychotic drugs increase health risks in dementia patients

Study found that antipsychotic drug use in dementia patients is linked to increased risks of stroke, heart failure, and other serious conditions.

18 Apr 2024

Antipsychotics for dementia associated with elevated risks of serious adverse outcomes

Antipsychotic use in people with dementia is associated with elevated risks of a wide range of serious adverse outcomes including stroke, blood clots, heart attack, heart failure, fracture, pneumonia, and acute kidney injury, compared with non-use, finds a study published by The BMJ today.

17 Apr 2024

Study finds dysfunction of key brain systems in people with psychosis

Inside the brains of people with psychosis, two key systems are malfunctioning: a "filter" that directs attention toward important external events and internal thoughts, and a "predictor" composed of pathways that anticipate rewards.

13 Apr 2024

Study finds racial disparities in chemical sedation rates for psychiatric patients in the EDs

Black patients presenting at Emergency Departments (EDs) across the country with psychiatric complaints are 63 percent more likely to be chemically sedated than their white counterparts.

8 Apr 2024

Ketogenic diet can be a powerful aid in treating mental illness

For people living with serious mental illness like schizophrenia or bipolar disorder, standard treatment with antipsychotic medications can be a double-edged sword.

1 Apr 2024

Antipsychotic use during pregnancy not linked to childhood neurodevelopmental disorders or learning difficulties

The use of antipsychotics during pregnancy isn't linked to childhood neurodevelopmental disorders or learning difficulties, UNSW Sydney-led study shows – giving assurance to those concerned about continuing their medications during pregnancy.

18 Mar 2024

Pomegranate seed oil boosts brain function in mild cognitive impairment study

Study demonstrates that pomegranate seed oil (PSO) combined with the Mediterranean Diet (MeDi) significantly enhances cognitive functions in individuals with mild cognitive impairment (MCI), suggesting PSO as a potential natural intervention for cognitive health.

5 Feb 2024

Cedars-Sinai pioneers method to identify dementia patients for better care

Cedars-Sinai investigators are using electronic health records to identify hospitalized patients likely to have dementia.

12 Jan 2024

AI models for mental health hit generalizability snag

Scientists from Yale and the University of Cologne were able to show that statistical models created by artificial intelligence (AI) predict very accurately whether a medication responds in people with schizophrenia.