Antipsychotics are medicines used to treat the symptoms of mental disorders such as schizophrenia, depression, bipolar disorder (sometimes called manic-depressive illness), anxiety disorders, and attention deficit-hyperactivity disorder (ADHD). Sometimes medications are used with other treatments such as psychotherapy.
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Researchers assessed the impact of ceramide (CER) and cholesterol (CHOL) on membrane fusion mediated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.
Gold standard treatment plans for people with early psychosis have a patchy success rate, suggesting the need to develop more tailored approaches.
Researchers conducted a retrospective study to determine whether SSRIs with immunomodulatory and antiplatelet properties can decrease the risk of post-acute sequelae of COVID-19 (PASC).
Researchers at the Lieber Institute for Brain Development (LIBD) believe they have solved a riddle that has challenged scientists for more than 70 years: how the brain chemical dopamine relates to schizophrenia, the often-devastating brain disorder characterized by delusional thinking, hallucinations and other forms of psychosis.
People with psychotic disorders such as schizophrenia are 2.5 times more likely than those without a psychotic disorder to eventually develop dementia, according to a review of evidence led by UCL researchers.
Can you teach an old drug new tricks? Although drug treatments for the core symptoms of autism spectrum disorder (ASD) are not currently available, could an existing drug provide a new treatment, even if it previously had no association with ASD? This was the question asked by a new study in the journal Frontiers in Pharmacology. The researchers used a computer model that encompasses proteins involved in ASD and the way they interact.
A research team from the Centre for Safe Medication Practice and Research (CSMPR), Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) conducted the world's first systematic review and meta-analysis of observational studies with over two million individuals and estimated a moderate association between antipsychotic use and breast cancer by over 30%.
Announcing a new article publication from Acta Pharmaceutica Sinica B. The brain is the most advanced organ with various complex structural and functional microregions.
To be decided by the editor
Younger onset dementia has a devastating impact on the lives of people diagnosed and their families, with many developing complex care needs as their illness progresses. In a new study of 5,400 people with younger onset dementia by the Australian Institute of Health and Welfare (AIHW), over half (58%) required permanent residential aged care, with 25% of these people aged under 65 at the time of entry to care.
To treat some of the psychosis issues associated with Parkinson's disease, physicians often prescribe pimavanserin, an antipsychotic drug that acts within the brain to prevent hallucinations and delusions.
Research teams at Mass General Brigham's founding members, Brigham and Women's Hospital and Massachusetts General Hospital, have been approved for more than $50 million in funding awards by the Patient-Centered Outcomes Research Institute for studies focused on treating two important mental health conditions.
In a new study, researchers identified a papain-like protease inhibitor for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.
New research evaluated the recent usage of marijuana and its derivative products, their effects and clinical manifestations, perceptions, pharmaceutics, epidemiological studies, and the long-term ramifications in pediatric populations.
A decade-long effort to reduce medication risks for nursing home residents with dementia has paid off in some ways – but produced unintended consequences that now need addressing, new research shows.
Mariel needed a new gastroenterologist. Having just moved back to San Antonio, the 30-something searched for a doctor to manage her Crohn's disease, an inflammatory bowel condition that is successfully managed with medications and lifelong monitoring — including regular colonoscopies.
Scientists have published a review study in the Journal for Nurse Practitioners that has focussed on various aspects of the use of cannabidiol in Parkinson's.
Herbal supplements may be natural, but that does not mean they are always safe. A new case report appearing in Heart Rhythm Case Reports, an official journal of the Heart Rhythm Society, published by Elsevier, is a case in point.
A literature review in Harvard Review of Psychiatry indicates that, while transcranial electrical stimulation (tES) has rarely been used in treating visual hallucinations (VH) among patients with psychiatric disorders, recent advances in neuroimaging technology show promise in helping tES to more effectively treat VH in psychiatric disorders where VH are a core symptom.