Antipsychotic News and Research

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Antipsychotics are medicines used to treat the symptoms of mental disorders such as schizophrenia, depression, bipolar disorder (sometimes called manic-depressive illness), anxiety disorders, and attention deficit-hyperactivity disorder (ADHD). Sometimes medications are used with other treatments such as psychotherapy.

Study confirms QT-prolonging effects of grapefruit juice

Grapefruit juice is already listed as a substance to avoid when taking QT-prolonging medications because it increases the toxicity of many drugs.

9 May 2019

Compound derived from broccoli sprouts may restore brain chemistry imbalance related to schizophrenia

In a series of recently published studies using animals and people, Johns Hopkins Medicine researchers say they have further characterized a set of chemical imbalances in the brains of people with schizophrenia related to the chemical glutamate.

From Johns Hopkins Medicine 9 May 2019

Meth vs. opioids: America has two drug epidemics, but focuses on one

Kim had been wine tasting with a friend in Sonoma, Calif. They got into an argument in the car that night and Kim thought someone was following them. She was utterly convinced. And she had to get away.

7 May 2019

Texting helps improve medication adherence, health outcomes for patients with schizophrenia

Texting patients with schizophrenia and their lay health supporters in a resource-poor community setting is more effective than a free-medicine program alone in improving medication adherence and reducing relapses and re-hospitalizations, according to a study published April 23 in the open-access journal PLOS Medicine by Wenjie Gong of Central South University in Hunan, China, Dong (Roman) Xu of Sun Yat-sen University Global Health Institute, Guangdong, China and colleagues.

24 Apr 2019

Pregnant women with type 1 diabetes are at greater risk of preterm birth

Pregnant women with type 1 diabetes are at increased risk of delivering their baby prematurely. The risk increases as blood sugar levels rise, however women who maintain the recommended levels also risk giving birth prematurely.

23 Apr 2019

Study provides new insights into regulatory T cells' role in protecting against autoimmune disease

An international study led from Karolinska Institutet provides new insights into the regulatory T cells' role in protecting against autoimmune disease.

23 Apr 2019

Scientists identify 104 high-risk genes for schizophrenia

Using a unique computational "framework" they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute has identified 104 high-risk genes for schizophrenia.

23 Apr 2019

Initial gene analysis could result in more effective antipsychotic treatment

An initial gene analysis may yield better outcomes when patients are treated with the antipsychotic drugs risperidone and aripiprazole.

16 Apr 2019

Watchdogs cite lax medical and mental health treatment of ICE detainees

It’s Saturday morning and the women of the Contreras family are busy in Montclair, Calif., making pupusas, tamales and tacos. They’re working to replace the income of José Contreras, who has been held since last June at Southern California’s Adelanto ICE Processing Center, a privately run immigration detention center.

15 Apr 2019

Making smarter decisions about where to recover after hospitalization

Every year, nearly 2 million people on Medicare — most of them older adults — go to a skilled nursing facility to recover after a hospitalization. But choosing the facility can be daunting, according to an emerging body of research.

11 Apr 2019

New study offers insight into development of delusions

Delusions are one of the most common symptoms of psychosis, but little is known about what causes them. A new study from researchers at Columbia University and New York State Psychiatric Institute offers insight into the development of delusions, which could lead to better treatments for people with psychosis.

22 Mar 2019

Roundworm study suggests alternatives for treatment of schizophrenia

A group of Brazilian scientists have long conducted experiments with roundworms to investigate the role of schizophrenia-linked genes in patients' response to antipsychotic drugs. The results obtained thus far point to new ways of understanding resistance to certain classes of medication.

20 Mar 2019

Changing drugs, deprescribing do not lower severity and duration of delirium in ICU patients

The results of two new Regenstrief Institute trials published in the Journal of the American Geriatrics Society underscore and confirm the need to look to options other than medication to lower the duration or severity of delirium in intensive care unit patients.

6 Mar 2019

Study sheds new light on early development of embryos

By applying gene analysis to individual cells from early mouse embryos, researchers at Karolinska Institutet in Sweden have discovered previously unknown cellular stages of fetal development from fertilized egg to living being. The study is published in the scientific journal Cell Reports.

5 Mar 2019

Researchers discover new and rare skeletal disease

Researchers at Karolinska Institutet in Sweden have discovered a new and rare skeletal disease. In a study published in the journal Nature Medicine they describe the molecular mechanism of the disease, in which small RNA molecules play a role that has never before been observed in a congenital human disease.

25 Feb 2019

Some drug combinations may be more effective than others for schizophrenic patients

Patients with schizophrenia are often treated with more than one type of psychiatric medication, but a new study suggests that some combinations may be more effective than others.

21 Feb 2019

Research finds steep rise in self-poisonings among young people

Self-harm from self-poisoning in children and adolescents is not only increasing but starting at a younger age, finds new research by University of Sydney and the NSW Poisons Information Centre.

20 Feb 2019

Antipsychotic polypharmacy may be beneficial for schizophrenia patients

Combining certain types of two antipsychotic agents in the maintenance treatment of schizophrenia is associated with a lower risk of relapse than using monotherapy. T

20 Feb 2019

Violence, malnutrition and lack of care reported in huge numbers in Australia's aged care system

According to the reports of a recent inquiry, inspectors looking at aged care homes in Australia over the last year have reported an alarming rise in missing residents, violence that was not reported and severe degrees of malnutrition among the residents.

12 Feb 2019

Improvements in pharmacological study to fight cognitive impairment in schizophrenia

A study by the UPV/EHU has assessed the effectiveness of various drugs, which are used to delay cognitive deterioration in patients with Alzheimer's, in improving cognitive impairment displayed by patients with schizophrenia.

17 Jan 2019