Antiretroviral News and Research

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Well-armed immune cells help long-term non-progressors contain HIV

To help develop an effective HIV vaccine, researchers are trying to better understand how the immune systems of a small minority of HIV-infected people known as long-term non-progressors (LTNPs) contain the virus naturally.

5 Dec 2008

New insights into development of the human immune system

A UCSF study has found that a surprisingly high number of maternal cells enters the fetus during pregnancy, prompting the generation of special immune cells in the fetus that suppress a response against the mother.

5 Dec 2008

Extraordinary immune cells may hold the key to managing HIV

People who manage to control HIV on their own are providing scientists with valuable information about how the immune system eliminates virus-infected cells.

5 Dec 2008

WHO boss says major milestone reached in fight against AIDS

Dr. Margaret Chan, WHO Director-General says a major milestone in the long struggle against HIV/AIDS has been reached.

3 Dec 2008

20th anniversary of World AIDS day - experts say universal, voluntary testing could reduce new HIV cases by 95%

December the 1st 2008 marked the 20th anniversary of World AIDS day - a day when people around the world take stock of the AIDS situation and consider those who have died from the disease and those who are struggling to live with it.

1 Dec 2008

Universal voluntary testing, immediate treatment can reduce new HIV cases by 95% within 10 years

Universal and annual voluntary testing followed by immediate antiretroviral therapy treatment (irrespective of clinical stage or CD4 count) can reduce new HIV cases by 95% within 10 years, according to new findings based on a mathematical model developed by a group of HIV specialists in WHO.

26 Nov 2008

AHF: Lancet’s Africa AIDS study shows global testing woefully under-funded

A study published in the British medical journal Lancet yesterday suggesting that testing all adults in Africa annually for HIV and immediately treating every person who tests positive could halt the AIDS epidemic in Africa within a decade has spurred the AIDS Healthcare Foundation (AHF) to renew its call for the massive scale up of, and dramatically increased funding for global HIV testing and antiretroviral treatment worldwide.

26 Nov 2008

Selzentry (maraviroc) becomes fully approved HIV antiretrovial

The U.S. Food and Drug Administration (FDA) has granted Selzentry (maraviroc) full (traditional) approval for use in treatment-experienced adults with CCR5-tropic HIV-1 in combination with other antiretrovirals.

25 Nov 2008

AIDS advocates tell WHO: Stop harmful single-dose treatment for expectant mothers and infants

As World AIDS Day 2008 approaches, a coalition of hundreds of HIV/AIDS medical care providers and advocates, representing dozens of organizations, today sent a letter to Dr. Margaret Chan, Director General of the World Health Organization (WHO), urging an end to harmful single-dose HIV/AIDS treatment as a recommended treatment for expectant mothers and infants worldwide.

25 Nov 2008

Results out from first phase III randomized clinical trial to study the best time to begin ART in infants

Testing very young babies for HIV and giving antiretroviral therapy (ART) immediately to those found infected with the virus dramatically prevents illness and death, according to a report in the New England Journal of Medicine.

19 Nov 2008

Genetic Immunity announces first patient dosed in trial with DermaVir patch for HIV

Genetic Immunity, a US/Hungarian clinical-stage company focused on development of nanomedicines for targeted immune amplification, today announced it has treated the first subject in a Phase II clinical study to evaluate DermaVir Patch.

13 Nov 2008

Astragalus root plant chemical used to fight HIV

Like other kinds of cells, immune cells lose the ability to divide as they age because a part of their chromosomes known as a telomere becomes progressively shorter with cell division.

11 Nov 2008

Protein called TIM-3 turns off HIV-fighting T cells

In HIV-infected patients the body's immune system is unable to fight off the virus.

11 Nov 2008

Cells exhausted from fighting HIV infection can be rescued

Researchers at the University of Toronto and the University of California, San Francisco, have revealed new hope for HIV treatment with the discovery of a way to 'rescue' immune cells that are exhausted from fighting off HIV infection.

11 Nov 2008

Scientists engineer T cells to recognize HIV-1 strains that have evaded the immune system

The findings of the study, published online in the journal Nature Medicine, have important implications for developing new treatments for HIV, especially for patients with chronic infection who fail to respond to antiretroviral regimens.

10 Nov 2008

New tuberculosis vaccine safer, more effective than BCG vaccine for HIV-positive people

A new tuberculosis vaccine could be safer and more effective than the currently available BCG vaccine, particularly for HIV-positive people, according to a study to be published in the November issue of Infection and Immunity, IANS/Times of India reports (IANS/Times of India, 10/24).

28 Oct 2008

The sooner the better when it comes to HIV/AIDS treatment

New research into HIV/AIDS therapy has found that starting treatment with drugs for the AIDS virus may be better sooner than later as victims are more than 70% less likely to die when they started taking cocktails of HIV drugs earlier than currently recommended.

27 Oct 2008

CytoDyn files new IND for Cytolin

CytoDyn, Inc. has filed a new IND for a study to reconfirm dose ranging and to "prove the principle" with a randomized, double-blind placebo controlled study of Cytolin, the Company's first-in-class drug for treating HIV/AIDS. This comes 13 years after the first IND was issued for the drug.

22 Oct 2008

Researchers identify novel type of antibody that potently inhibits HIV infection

A small antibody fragment that is highly effective in neutralizing the human immunodeficiency virus (HIV) by preventing the virus from entering cells has been identified by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

21 Oct 2008

Antiretroviral drug efavirenz associated with better outcomes in HIV-infected adults

A study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that HIV-infected patients taking the antiretroviral drug efavirenz were more likely to adhere to treatment and less likely to experience virologic failure and death compared to patients taking nevirapine.

14 Oct 2008

Antiretroviral News and Research

Well-armed immune cells help long-term non-progressors contain HIV

New insights into development of the human immune system

Extraordinary immune cells may hold the key to managing HIV

WHO boss says major milestone reached in fight against AIDS

20th anniversary of World AIDS day - experts say universal, voluntary testing could reduce new HIV cases by 95%

Universal voluntary testing, immediate treatment can reduce new HIV cases by 95% within 10 years

AHF: Lancet’s Africa AIDS study shows global testing woefully under-funded

Selzentry (maraviroc) becomes fully approved HIV antiretrovial

AIDS advocates tell WHO: Stop harmful single-dose treatment for expectant mothers and infants

Results out from first phase III randomized clinical trial to study the best time to begin ART in infants

Genetic Immunity announces first patient dosed in trial with DermaVir patch for HIV

Astragalus root plant chemical used to fight HIV

Protein called TIM-3 turns off HIV-fighting T cells

Cells exhausted from fighting HIV infection can be rescued

Scientists engineer T cells to recognize HIV-1 strains that have evaded the immune system

New tuberculosis vaccine safer, more effective than BCG vaccine for HIV-positive people

The sooner the better when it comes to HIV/AIDS treatment

CytoDyn files new IND for Cytolin

Researchers identify novel type of antibody that potently inhibits HIV infection

Antiretroviral drug efavirenz associated with better outcomes in HIV-infected adults

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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