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Researchers receive NIH grant to help develop gene therapy for HIV

Researchers at Washington University School of Medicine in St. Louis have received a $6.2 million grant from the National Institutes of Health (NIH) to develop a gene therapy that would modify the immune system's B cells to spur them to produce broadly neutralizing antibodies against HIV.

18 Apr 2024

Study reveals increased risk of immune abnormalities in children of women with HIV

Researchers have found that children of women with HIV infection have an increased risk of immune abnormalities following exposure to maternal HIV viremia, immune dysfunction, and co-infections during pregnancy.

17 Apr 2024

Global HIV epidemic cannot be ended without keeping former prisoners, other patients engaged in care

New data from an implementation programme to be presented at this year's the ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) stress that the global HIV epidemic cannot be ended without keeping former prisoners and other patients engaged in care, and outlines the efforts made by HIV care clinics in Chicago to locate formerly incarcerated individuals living with HIV who dropped out of care and to reconnect them with treatment services.

16 Apr 2024

Common HIV drugs linked to reduced Alzheimer's disease risk

Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need.

16 Apr 2024

Sugar abnormalities in the blood may promote biological aging and inflammation in HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., along with his team and collaborators, has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV (PLWH).

10 Apr 2024

Increased coronary vessel wall thickness linked to heart dysfunction in asymptomatic HIV patients

A new study found increased coronary vessel wall thickness that was significantly associated with impaired diastolic function in asymptomatic, middle-aged individuals living with HIV.

4 Apr 2024

New report on HIV drug resistance: Challenges and recommendations

The World Health Organization's (WHO) latest HIV Drug Resistance (HIVDR) Report tells us where drug resistance is growing and offers recommendations for countries to monitor and respond to the potential challenges.

1 Apr 2024

Rethinking PrEP's role in prevention of sexually transmitted infections

In their research article published in Eurosurveillance, von Schreeb et al. challenge existing assumptions regarding the relationship between the use of HIV pre-exposure prophylaxis (PrEP) and the incidence of bacterial sexually transmitted infections (STI).

28 Mar 2024

Breakthrough study offers hope for an effective HIV cure

By 2030, the World Health Organization (WHO), the Global Fund and UNAIDS are hoping to end the human immunodeficiency virus (HIV) and AIDS epidemic.

26 Mar 2024

New drug candidates show promise to reverse HIV immune evasion

University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.

19 Mar 2024

Social workers bridge the gap in HIV care for hospitalized patients in Tanzania

Researchers at Weill Cornell Medicine have shown that three months of social worker follow-up support to people hospitalized with HIV in Tanzania had health benefits at low cost.

11 Mar 2024

Vaginal ring and oral PrEP found to be safe for HIV prevention among pregnant cisgender women

The monthly dapivirine vaginal ring and daily oral pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate and emtricitabine were each found to be safe for HIV prevention among cisgender women who started using one of them in their second trimester of pregnancy, according to findings presented today at the 2024 Conference on Retroviruses and Opportunistic Infections (CROI) in Denver.

5 Mar 2024

Study shows semaglutide as a safe and effective therapy for MASLD in people with HIV

A weekly injection of semaglutide was safe and reduced the amount of fat in the liver by 31% in people with HIV and metabolic dysfunction-associated steatotic liver disease (MASLD), according to a presentation today at the 2024 Conference on Retroviruses and Opportunistic Infections (CROI) in Denver.

5 Mar 2024

City of Hope cures oldest person of blood cancer and achieves HIV remission

City of Hope, one of the largest cancer research and treatment organizations in the United States, treated the oldest person to be cured of a blood cancer and then achieve remission for HIV after receiving a blood stem cell transplant from a donor with a rare genetic mutation.

15 Feb 2024

Combination therapy shows promise in targeting latent HIV reservoirs

Antiretroviral therapies (ART) stop HIV replication in its tracks, allowing people with HIV to live relatively normal lives.

15 Feb 2024

U of M research offers new avenue of hope in the fight against chronic HIV

Published in the Journal of Infectious Diseases Oxford Academic, research led by the University of Minnesota Medical School offers a new avenue of hope in the fight against chronic human immunodeficiency virus (HIV) infection.

14 Feb 2024

Vaccines safe for pregnant women with HIV but show reduced immune response

A meta-analysis in eClinicalMedicine finds vaccines are safe for pregnant women living with HIV, showing reduced immunogenicity compared to those without HIV but no increase in adverse events, highlighting the need for their inclusion in vaccine trials.

9 Feb 2024

Paxlovid enhances treatment options for COVID-19 patients

The design, synthesis, and mechanism of action of Paxlovid.

6 Feb 2024

New study reveals key tissues involved in HIV rebound after treatment

In findings that have implications for potential new HIV therapies, researchers from Texas Biomedical Research Institute (Texas Biomed) used genetic sequencing techniques on the nonhuman primate version of the virus to identify that lymph nodes in the abdomen are the leading source of rebound infection after the first week of stopping antiretroviral treatment.

24 Jan 2024

Anti-HIV drugs can be used to prevent inflammatory complications of bacterial sepsis

Bacterial infections can lead to the formation of abscesses -; pockets of dead cells and debris surrounded by inflammatory immune cells. Bacteria multiply within abscesses, causing more inflammation and further damage to surrounding tissues.

17 Jan 2024