Antiretroviral News and Research

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Discovery of dopamine terminal injury in brains of people with HIV dementia

Scientists at the U.S. Department of Energy’s Brookhaven National Laboratory have discovered a key mechanism in the brains of people with human immunodeficiency virus (HIV) dementia.

20 Sep 2004

WHO urges Member States to act now to avoid a major HIV/AIDS epidemic

Dr Shigeru Omi, World Health Organization Regional Director for the Western Pacific, has warned of the danger of HIV "bridging" into the general population from infected individuals with high-risk behaviour unless countries and areas in the Region act now to avoid a major HIV/AIDS epidemic.

16 Sep 2004

Early use of combination-drug treatments could improve HIV survival rates

Survival rates of HIV-positive patients could be improved if combination-drug treatment were begun earlier than current clinical guidelines now recommend, according to a new study by researchers from The New York Academy of Medicine and the Johns Hopkins University Bloomberg School of Public Health.

14 Sep 2004

Researchers uncover how HIV causes abnormalities in antibody-producing cells

HIV wreaks much of its damage by targeting the “orchestra conductor” of the immune system, a key class of T cells—CD4+ T cells—whose destructive relationship with HIV has been well-studied by AIDS researchers.

8 Sep 2004

Generic tritherapy can be used as a basic treatment for AIDS

A clinical trial, conducted in Cameroon by IRD researchers working with other organizations and supported by the ANRS, has demonstrated that one of the most common combinations currently deployed in Africa, using nevirapine, stavudine and lamivudine, satisfies these criteria.

5 Sep 2004

Highly active antiretroviral therapies for AIDS are not initiated soon enough

Highly active antiretroviral therapy (HAART) has been shown to delay progression of AIDS and reduce mortality, yet the optimal time to start it is unknown.

2 Sep 2004

FDA reinforces use of Sustiva in first-line HIV combination therapy

Bristol-Myers Squibb has announced that Sustiva® (efavirenz) has received approval from the U.S. Food and Drug Administration to include new long-term virologic and clinical data from BMS Study 006 in its prescribing information.

26 Aug 2004

Clinicians have been able to reduce mortality rates in HIV positive children from 15 to 3 percent

"This is perhaps the first time that it has been demonstrated that HIV positive children can be successfully treated with antiretroviral therapy in resource-limited settings and the outcomes are comparable to those we have seen in U.S. pediatric antiretroviral clinical trials,"

23 Aug 2004

New information about how HIV evades eradication from the body

Researchers at the National Cancer Institute, have discovered new information about how human immunodeficiency virus (HIV), the virus that causes acquired immune deficiency (AIDS), possibly evades eradication from the body.

23 Aug 2004

Discovery of new ways to manipulate AIDS virus

16 Aug 2004

People living with HIV in rural communities may face different barriers to taking proper care of themselves

People who live with HIV in rural areas are less likely to keep up with their treatment schedules if they are problem drinkers, say Tulane University researchers. Overall, about one in three HIV positive people surveyed by the researchers reported skipping at least one dose of their medications in the past week.

7 Aug 2004

Bush administration is depriving millions access to life-saving generic drugs

AIDS Healthcare Foundation, has commended the World Health Organization (WHO) for their leadership and sincere interest in ensuring the safety of generic HIV/AIDS drugs in the developing world.

6 Aug 2004

Approval of fixed-dose combination treatments for HIV-1 infection

The Food and Drug Administration has announced the approvals of Epzicom (abacavir/lamivudine) and Truvada (tenofovir disoproxil/emtricitabine), two fixed-dose combination treatments for HIV-1 infection.

5 Aug 2004

Approval of an injectable filler to correct facial fat loss in people with HIV/AIDS

The Food and Drug Administration has approved an injectable filler to correct facial fat loss in people with human immunodeficiency virus (HIV) infection.

5 Aug 2004

FDA approves two fixed-dose combination treatments for HIV-1 infection

The Food and Drug Administration has announced approved Epzicom (abacavir/lamivudine) and Truvada (tenofovir disoproxil/emtricitabine), two fixed-dose combination treatments for HIV-1 infection.

2 Aug 2004

Mining giant Rio Tinto has developed and implemented a global HIV/AIDS strategy

Rio Tinto’s response to HIV/AIDS draws upon the International Labour Organisation (ILO) Code of Good Practice on HIV/AIDS. Discrimination towards employees on the basis of real or perceived HIV status is not tolerated. The confidentiality of all information on the HIV status and condition of employees and community members is strictly upheld.

2 Aug 2004

Inexpensive generic three-in-one fixed-dose combination pill taken twice a day has helped HIV/AIDS patients in Uganda

The Arua Hospital AIDS Program today commemorated two years of providing free access to antiretroviral (ARV) treatment for nearly 1,100 people living with HIV/AIDS in Arua, a rural region in northwestern Uganda.

2 Aug 2004

New drug combination more effective than the previous generation of hepatitis C/HIV therapy

A new study reveals the highest efficacy rates ever reported among patients co-infected with hepatitis C and HIV treated with pegylated interferon and ribavirin.

28 Jul 2004

Latin America still not faced a large-scale AIDS epidemic

Although the risk patterns that favor the expansion of HIV are very widespread, the majority of the countries of Latin America have still not faced a large-scale AIDS epidemic, according to a publication by the Pan American Health Organization and the World Bank.

26 Jul 2004

New guidelines for antiretroviral drugs to prevent the transmission of HIV from mothers to their children

The World Health Organization has published new guidelines underlining the effectiveness of antiretroviral drugs to prevent the transmission of HIV from seropositive mothers to their children.

15 Jul 2004