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Study discovers genetic variations that increase heart attack risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

10 May 2018

Study reveals increased risks for Alzheimer's, suicide among youth in polluted cities

A University of Montana researcher and her collaborators have published a new study that reveals increased risks for Alzheimer's and suicide among children and young adults living in polluted megacities.

16 Apr 2018

Researchers get one step closer to creating peptide vaccine against atherosclerosis

In the disease atherosclerosis, cholesterol-containing plaques form in vessel walls, causing arteries to narrow and greatly increasing the risk of heart attack and stroke.

12 Apr 2018

Study reveals how apoE4 gene confers risk for Alzheimer's disease in brain cells

Using human brain cells, scientists at the Gladstone Institutes discovered the cause of--and a potential solution for--the primary genetic risk factor for Alzheimer's disease, a gene called apoE4.

9 Apr 2018

High-fat, high-cholesterol diet depletes ranks of artery-protecting immune cells

New research from scientists at the La Jolla Institute for Allergy and Immunology shows how a diet high in fat and cholesterol depletes the ranks of artery-protecting immune cells, turning them into promoters of inflammation, which exacerbate atherosclerotic plaque buildup that occurs in cardiovascular disease.

21 Mar 2018

E-cigarette use linked to fat accumulation in the liver

Using e-cigarettes may lead to an accumulation of fat in the liver, a study of mice exposed to the devices suggests.

19 Mar 2018

PCSK9 inhibitor reduces cardiovascular events in ACS patients with high cholesterol

Among patients with persistently high cholesterol despite high-intensity statin therapy, the proprotein convertase subtilisin-kexin 9 (PCSK9) inhibitor alirocumab reduced rates of major adverse cardiovascular events by 15 percent compared with placebo, in a study presented at the American College of Cardiology's 67th Annual Scientific Session.

12 Mar 2018

Cholesterol and other lipids in the blood play role in many diseases

Lipids are fatty molecules that play important signaling and storage roles in the body, but having an excess of some lipids, like cholesterol, is a risk factor for many metabolic diseases.

8 Feb 2018

Substituting animal proteins with plant proteins could reduce main cholesterol markers, study suggests

Substituting one to two servings of animal proteins with plant proteins every day could lead to a small reduction in the three main cholesterol markers for cardiovascular disease prevention, a new study suggests.

21 Dec 2017

Researchers uncover link between abdominal aortic aneurysm and dysregulated tryptophan metabolism

Researchers have found a link between dysregulated tryptophan metabolism and abdominal aortic aneurysm, a life-threatening vascular disease, according to a new study led by Georgia State University.

13 Nov 2017

Inflammation in mid-life may be linked to brain shrinkage decades later

People who have biomarkers tied to inflammation in their blood in their 40s and 50s may have more brain shrinkage decades later than people without the biomarkers, according to a study published in the November 1, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology. The brain cell loss was found especially in areas of the brain that are affected by Alzheimer's disease.

2 Nov 2017

Wake Forest Baptist receives NIH grants to study risks associated with kidney transplants

The National Institutes of Health has awarded two five-year grants to Wake Forest Baptist Medical Center worth more than $5 million to prospectively study the effects of a genetic variation in organ donors that appears to contribute to survival of kidneys after transplantation.

3 Oct 2017

Impairing critical partnership between brain cells can lead to Alzheimer's disease

Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration. The study published in Cell Metabolism reports a mechanism by which two types of brain cells, neurons and glia, normally support each other's functions.

30 Sep 2017

Decreasing sedentary time 21 minutes per day can help maintain muscle mass, health

Finnish researchers conducted one of the largest and longest studies to find out if it is possible to reduce sedentary time and if the reduction will result in any health benefits during one year.

30 Aug 2017

Moderate intake of carbohydrate and fat associated with better health, says global study

An international study suggests that a diet consisting of a moderate consumption of fat, fruits and vegetables, coupled with avoidance of high levels of carbohydrates, is linked with a decreased risk of death.

30 Aug 2017

Moderate intake of nutrients found to be best for health

Research with more than 135,000 people across five continents has shown that a diet which includes a moderate intake of fat and fruits and vegetables, and avoidance of high carbohydrates, is associated with lower risk of death.

29 Aug 2017

Clinical benefit of LDL cholesterol lowering therapies could depend on reduction in apoB particles

The benefit of lowering low-density lipoprotein (LDL) cholesterol depends on how it is lowered, according to late-breaking results from a naturally randomised genetic trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in JAMA.

29 Aug 2017

Studies aim to better understand potential health benefits of red raspberries

Initial findings from several studies - including both human subjects and animals - on the potential health benefits of red raspberries were presented earlier this year at the 2017 Experimental Biology conference in Chicago.

24 Aug 2017

People with genetic susceptibility to Alzheimer's may have greater cognitive deficits with sleep-disordered breathing

People who carry a genetic susceptibility to Alzheimer's disease appear to be at greater risk of diminished cognition from sleep-disordered breathing than those without the susceptibility, according to new research published online, ahead of print in the Annals of the American Thoracic Society.

21 Jul 2017

Targeting risk factors throughout life stages could prevent 35% of dementia cases, study reveals

A study published in The Lancet, on July 20th 2017, reveals that 1 out of 3 dementia cases are preventable when risk factors are targeted beginning from childhood.

20 Jul 2017