Apolipoprotein News and Research

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Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

In a recent study published in the Journal of the Alzheimer's Association (AA), researchers examined the effects of a low-carbohydrate-modified Mediterranean ketogenic diet (MMKD) on the gut microbiome and metabolome of patients at risk for Alzheimer's disease (AD).

9 Apr 2023

The association between omega-3 polyunsaturated fatty acid intake and reduced risk of Alzheimer's disease

Researchers evaluated the association between omega-3 polyunsaturated fatty acids intake, cognitive decay, and dementia.

7 Apr 2023

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Researchers reviewed the existing knowledge on the mechanisms through which DNA tumor viruses evade the antiviral immunity mediated through mis-incorporated uracil (U).

3 Apr 2023

The association between regular glucosamine use and risk of dementia

Researchers assessed the association between daily glucosamine consumption and the risk of new-onset dementia.

3 Apr 2023

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

A recent review published in Biochemical Pharmacology summarized the ongoing research, providing insights into pathophysiology and emerging drugs for Alzheimer’s disease (AD).

31 Mar 2023

Early life adversity linked to accelerated neurobiological aging, raising vulnerability to depression and Alzheimer's

scientists investigate the neurocognitive correlates of genetic vulnerability to major depressive disorder and Alzheimer's disease.

30 Mar 2023

New review examines link between HDLC and different types of cancer

Researchers summarized studies on the association between high-density lipoprotein cholesterol and different types of cancer

29 Mar 2023

Fiber intake associated with lower risk of cognitive decline in old people with ApoE ε4 genotype

Fiber intake is associated with a lower risk of developing cognitive decline in those old people with the Apolipoprotein E ApoE ε4 genotype, regarded as a genetic risk factor linked to the development of Alzheimer's disease.

22 Mar 2023

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Houston Methodist scientists reversed infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein, showing further evidence that links high cholesterol to female infertility.

15 Mar 2023

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

MK-0616, an experimental oral proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, met its primary endpoint and substantially reduced levels of low-density lipoprotein (LDL) cholesterol in people with high cholesterol and/or heart disease related to clogged arteries, in a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Keto-like diet may be associated with elevated risk of cardiovascular events

The ketogenic or "keto" diet, which involves consuming very low amounts of carbohydrates and high amounts of fats, has been gaining popularity.

5 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

Researchers investigate the role of neurotrophic factors on the cognitive performance of Alzheimer’s disease patients carrying the apolipoprotein E 4 gene.

1 Mar 2023

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Researchers characterize the effects of neuronal apolipoprotein E4 on Alzheimer’s disease-associated pathology.

23 Feb 2023

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

Can carbohydrate be reduced too low for weight loss, and glycemic control?

A new review in the Journal of Clinical Lipidology aimed to describe the definitions of carbohydrate-restricted dietary patterns, the potential benefits related to cardiometabolic risk factors, and whether healthcare professionals should consider it for glycemic management and weight loss.

9 Feb 2023

Apolipoprotein News and Research

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

The association between omega-3 polyunsaturated fatty acid intake and reduced risk of Alzheimer's disease

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

The association between regular glucosamine use and risk of dementia

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

Early life adversity linked to accelerated neurobiological aging, raising vulnerability to depression and Alzheimer's

New review examines link between HDLC and different types of cancer

Fiber intake associated with lower risk of cognitive decline in old people with ApoE ε4 genotype

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

Keto-like diet may be associated with elevated risk of cardiovascular events

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Can carbohydrate be reduced too low for weight loss, and glycemic control?

Study demonstrates intrahost MPXV variation within a single lesion

Study of older adults in China finds link between a healthy lifestyle and slower memory decline

Mpox has been silently circulating in non-mpox-endemic nations for 20 years, according to new study

How does the brain change with age?

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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