Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Scientists identifiy key compounds that stimulate stem cell growth in the brain

Scientists at Harvard University have identified key compounds that stimulate stem cell growth in the brain, which may one day lead to restored function for people affected by Parkinson's disease, strokes, multiple sclerosis, and a wide range of neurological disorders.

4 Sep 2006

Scientists trick cancer cells into suicide

Scientists in the U.S. believe they have found a way to trick cancer cells into committing suicide.

28 Aug 2006

Pomegranate juice may decrease PSA progression in patients with cancer recurrence after treatment

Because of their high content of antioxidants, pomegranate juice is frequently recommended for cancer prevention and overall wellness. While small studies have suggested a role against prostate carcinogenesis, no organized trials have been published until now.

17 Aug 2006

Birch bark compound may be potent prostate cancer fighter

A compound found in the bark of the white birch tree - betulonic acid, a derivative of betulinol - may finally have been rendered a water-soluble, bio-available drug, and is already showing the potential to be a possible agent against prostate cancer - in cell culture and in an animal model.

25 Jul 2006

Diblock copolymer micellar nanoparticles decorated with annexin-A5 proteins

One of the banes of modern cancer therapy is that clinicians and patients must often wait months before they can tell if a given treatment is working.

17 Jul 2006

Scientists discover promising new therapeutic target for heart disease

Scientists at the Boston Biomedical Research Institute identified Puma (p53 upregulated modulator of apoptosis) as a potential new target for the therapeutic intervention of heart disease.

10 Jul 2006

Scientists find a cytokine against auto-immune hepatitis

There are about 400 million patients of hepatitis in the world. Some of them are suffering from autoimmune hepatitis, a disease in which the body's immune system attacks liver cells.

5 Jul 2006

Gleevec strangles drug-resistant, metastatic prostate cancer

A medication used to treat other types of cancer strangles drug-resistant, metastatic prostate cancer by cutting off its blood supply, researchers from The University of Texas M. D. Anderson Cancer Center report in the June 7 issue of the Journal of the National Cancer Institute.

7 Jun 2006

Hydrophobic statins not associated with increased breast cancer risk

A report published in the Journal of the National Cancer Institute found that women who took statins--the widely used cholesterol lowering drugs--do not face an increased breast cancer risk as had been suggested by some previous studies.

6 Jun 2006

New data show Enzastaurin's activity across multiple cancer cell lines

Eli Lilly and Company's enzastaurin, an investigational, multi-targeted therapy that is currently the focus of two global Phase III clinical trials, one for the treatment of glioblastoma and one in non-Hodgkin's lymphoma

5 Jun 2006

Men with enlarged prostate can benefit from Botox injection

When researchers at the Chang Gung University Medical College, Taiwan and the University of Pittsburgh School of Medicine injected botulinum toxin A, or Botox, into the prostate gland of men with benign prostatic hyperplasia (BPH), a condition commonly referred to as enlarged prostate, they found that it eased symptoms and improved quality of life.

23 May 2006

Sulforaphane shown to inhibit the occurrence of hereditary colon cancer

Need another reason to eat vegetables? A new study at Rutgers shows that certain vegetables - broccoli and cauliflower, in particular - have natural ingredients that may reduce the risk of developing hereditary cancers.

17 May 2006

Exercise shown to protect against skin and bowel cancer

Two studies have shown that exercise can protect against skin and bowel cancer, and they have identified new mechanisms that could be responsible for this effect.

17 May 2006

Exercise protects against skin cancer

While doctors and scientists have long agreed that physical activity has health benefits, Rutgers cancer researcher Allan Conney and his New Jersey colleagues have found that exercise can even protect against skin cancer.

16 May 2006

Study sheds light on cancer susceptibility and disease involving bone-marrow failure

Defective protein production can occur in cells even when the genes controlling those proteins are normal, according to a new study to be published May 12 in Science.

12 May 2006

Inhibiting cell process may give cancer drug a boost

A molecule that interferes with the internal scaffolding that shapes the cell may kill cancer cells, retard the growth of tumors and give a boost to a common chemotherapy drug, according to findings appearing in the May 3 issue of the European Journal of Cancer.

3 May 2006

An engineered virus that tracks down and compels cancer cells to eat themselves

An engineered virus tracks down and infects the most common and deadly form of brain cancer and then kills tumor cells by forcing them to devour themselves, researchers at The University of Texas M. D. Anderson Cancer Center report.

3 May 2006

Three-dimensional breast cell cultures reveal clues to breast cancer hidden inside stem cells

Stem cells and how to boost them is hot on the research agenda. But stopping them could be critical too, as evidence implicating stem cells in cancer is mounting.

3 May 2006

Caspase-12 antagonists could potentially be useful in the treatment of sepsis and other inflammatory and immune disorders

According to the new study, the presence of caspase-12, which appears to modulate inflammation and innate immunity in humans, increases the body's "vulnerability to bacterial infection and septic shock" while a deficiency confers strong resistance to sepsis. This new discovery suggests that caspase-12 antagonists could be a potentially useful in the treatment of sepsis and other inflammatory and immune disorders.

26 Apr 2006

Kidney treatments may be improved with new understanding of cell death mechanism

Finding how two proteins conspire to get kidney cells to self-destruct when oxygen supplies are low may one day improve dismal mortality rates for ischemic renal failure, researchers say.

23 Apr 2006