Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.
The different genes within the genome must be expressed in precise levels and in the exact moment if the complex balance regulating cell activity is to be maintained.
As one of the most common malignant tumors, gastric cancer occupies the second leading cause of cancer-related deaths worldwide with an increasing trend.
Liver cancer is the second leading cause of cancer death worldwide. Two different forms of primary liver cancer cover the majority of cases: About 10 to 20 percent of those affected develop a bile duct carcinoma within the liver (intrahepatic cholangiocellular carcinoma; ICC), the far higher proportion of liver cancers are hepatocellular carcinomas.
Researchers have discovered a molecular pathway that controls the movement of mitochondria within breast cancer cells and influences invasiveness.
Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research.
Researchers at Queen's University Belfast have discovered a ground-breaking therapeutic process that can target and kill bowel cancer cells, which may improve survival rates for bowel cancer patients globally.
Verastem, Inc., operating as Verastem Oncology, a biopharmaceutical company focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced dosing of the first patient in a multicenter Phase I/II clinical trial at the Dana-Farber/Harvard Cancer Center of duvelisib in combination with venetoclax in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.
Researchers in Berlin have described significant differences in the brain immune cells (microglia) of male and female mice.
Atherosclerosis-;the narrowing of arteries due to plaque buildup-;is the underlying reason for the majority of strokes and heart attacks. When atherosclerosis occurs in the arteries that carry blood to the heart muscle, it is called coronary artery disease, the No. 1 killer of Americans.
Most neurons in the human brain live out their lives, enduring the processes of aging before eventually dying. Some, however, choose a more violent route: suicide.
Genetic testing is a powerful diagnostic tool that is increasingly being used for the diagnosis of dilated cardiomyopathy, a disease in which the heart becomes enlarged, making it difficult to pump blood. Cardiomyopathy affects more than 3.5 million people in the United States.
What if instead of daily insulin injections or wearing pumps, just getting a shot every few months could reverse Type 1 diabetes for you - or your dog?
Excessive body fat is associated with negative effects on female fertility and pregnancy. In mice, maternal obesity impairs proper development of egg precursor cells called oocytes.
An estimated 17 percent of humans worldwide die from cancer, but less than five percent of captive elephants-;who also live for about 70 years, and have about 100 times as many potentially cancerous cells as humans-;die from the disease.
According to a new study from the Stanford University School of Medicine programmed cell death or apoptosis follows a trigger and a ripple effect pattern.
Cancer tissue cells are divided into two major groups: cancer cells and cancer stem cells. CSCs are related to cancer progression and dissemination, so it's necessary to eradicate CSCs in order to cure cancer.
Johns Hopkins researchers in collaboration with Insilico Medicine, a biotechnology company based in Rockville Maryland, identify that silencing of the GULP1 gene expression by methylation plays an important role in ovarian carcinogenesis.
A new study in the American Journal of Pathology reports for the first time that injection of neuropeptide vasoactive intestinal peptide directly into the eye of mice enhanced corneal graft survival.
Doxorubicin is a chemotherapy drug widely used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart failure.
The strategy used by the Oropouche virus to replicate in human cells has been described for the first time by researchers at the University of São Paulo in Brazil and international collaborators in an article published in the journal PLOS Pathogens.