Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Investigating new cancer therapy candidates with live-cell imaging

There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs should work better than each alone.

From Essen BioScience, Inc. A Sartorius Company 16 Oct 2017

Newly discovered compound causes cancer cell death, whilst sparing healthy cells

Researchers have discovered a compound that can trigger cancer cells to self-destruct, without causing any damage to healthy cells.

10 Oct 2017

New treatment approach makes cancer cells commit suicide while sparing healthy cells

Scientists at Albert Einstein College of Medicine have discovered the first compound that directly makes cancer cells commit suicide while sparing healthy cells.

9 Oct 2017

Penn study explains how acute viral infections can linger

Infections caused by viruses, such as respiratory syncytial virus, or RSV, measles, parainfluenza, and Ebola, are typically considered acute. These viruses cause disease quickly and live within a host for a limited time. But in some cases, the effects of the infection, and presence of the virus itself, can persist.

6 Oct 2017

Study sheds light on the mechanism of lung damage in premature babies

The lungs are one of the last organs to undergo full maturation in a baby's body. Children that are born very prematurely do not have fully developed lungs, and are therefore more susceptible to associated complications.

30 Sep 2017

Drug approved to treat parasitic infections also exerts anti-tumor effect on EOC cells

Osaka Researchers, in partnership with other Japanese and U.S. scientists, report a new gene target, KPNB1, for treatment against epithelial ovarian cancer (EOC).

28 Sep 2017

MIPT scientist proposes unique model to predict cancer development

A scientist from the Moscow Institute of Physics and Technology has proposed a model that can predict the number of key carcinogenic events for each cancer type based on the relationship between morbidity and age.

26 Sep 2017

Research highlights problems with titanium based nanoparticles in joint implants

A team of researchers from Mayo Clinic have found that that Titanium Dioxide (TiO2) nanoparticles that are present in bone implants may be causing harm by impairing bone formation and interfering with resorption at the site of repair. This can lead to loosening of the implants and pain.

15 Sep 2017

AMSBIO's product portfolio covers cancer and cardiovascular research with new CD47 range

AMSBIO has announced a new range of CD47-relevant products suitable for rapid high throughput screening studies.

From AMS Biotechnology 13 Sep 2017

Researchers discover major mechanism in development of liver cancer

Liver cancer is the second-leading cause of cancer-related death and represents the fastest rising cancer worldwide. In most cases, the tumor develops in patients with chronic liver disease.

11 Sep 2017

Researchers find signaling pathway in cells that plays key role in development of fatty liver disease

Morbid obesity affects the liver: Almost one-third of all adults suffer from chronic fatty liver disease, which can lead to infections and even trigger cancer. Researchers at the University Children's Hospital Zurich and the University of Zurich have now found a signaling pathway in cells that play an important role in the development of fatty liver disease.

7 Sep 2017

STING signaling pathway induces apoptosis in T cells

EPFL scientists show that the STING signaling pathway, which helps coordinate the innate immune system, causes cell death in T cells of the adaptive immune system. This “killing” effect includes cancerous T cells, and has implications for treating T cell-derived cancers.

5 Sep 2017

Defect in DNA repair machinery causes underdevelopment of neural network

DNA is the computer code that programs every event in the body. Despite the importance of DNA fidelity, as the body develops, cells grow and replicate, DNA is constantly turned over. This repeated process can compromise the DNA, which is why the body has many DNA repair machineries.

30 Aug 2017

Study tests therapeutic effect of conventional and new cancer drug combinations

Cancer is one of the major causes of death worldwide affecting 8.2 million of people per year, and in the US, the number of new cases will achieve 1.6 million in 2017. The global impact of this disease costs a trillion of dollars, which makes critical the development of new drugs and treatment against it.

28 Aug 2017

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Concurrent administration of the T-cell stimulating anti-OX40 antibody and the immune checkpoint inhibitor anti-PD1 antibody attenuated the effect of anti-OX40 and resulted in poor treatment outcomes in mice.

28 Aug 2017

Gut bacterium can stop chemotherapy from causing cancer cell death

Researchers at Michigan Medicine and in China showed that a type of bacterium is associated with the recurrence of colorectal cancer and poor outcomes.

27 Jul 2017

Researchers discover potential chemical 'silver bullet' to reduce risk of colon cancer

In preclinical experiments, researchers at VCU Massey Cancer Center have uncovered a new way in which colon cancer develops, as well as a potential "silver bullet" for preventing and treating it.

26 Jul 2017

Wistar scientists discover new therapeutic strategy for difficult-to-treat form of ovarian cancer

A potential new therapeutic strategy for a difficult-to-treat form of ovarian cancer has been discovered by Wistar scientists. The findings were published online in Nature Cell Biology.

24 Jul 2017

Research shows how dietary essential fatty acids can help treat Alzheimer’s, other diseases

Understanding how dietary essential fatty acids work may lead to effective treatments for diseases and conditions such as stroke, Alzheimer's disease, age-related macular degeneration, Parkinson's disease and other retinal and neurodegenerative diseases.

18 Jul 2017

Scientists gain new insights into protein network that regulates programmed cell death

Researchers use a simplified model of a protein network to explain how apoptosis is regulated, whose malfunction is linked to cancer and neurodegenerative diseases.

14 Jul 2017

Apoptosis News and Research

Investigating new cancer therapy candidates with live-cell imaging

Newly discovered compound causes cancer cell death, whilst sparing healthy cells

New treatment approach makes cancer cells commit suicide while sparing healthy cells

Penn study explains how acute viral infections can linger

Study sheds light on the mechanism of lung damage in premature babies

Drug approved to treat parasitic infections also exerts anti-tumor effect on EOC cells

MIPT scientist proposes unique model to predict cancer development

Research highlights problems with titanium based nanoparticles in joint implants

AMSBIO's product portfolio covers cancer and cardiovascular research with new CD47 range

Researchers discover major mechanism in development of liver cancer

Researchers find signaling pathway in cells that plays key role in development of fatty liver disease

STING signaling pathway induces apoptosis in T cells

Defect in DNA repair machinery causes underdevelopment of neural network

Study tests therapeutic effect of conventional and new cancer drug combinations

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Gut bacterium can stop chemotherapy from causing cancer cell death

Researchers discover potential chemical 'silver bullet' to reduce risk of colon cancer

Wistar scientists discover new therapeutic strategy for difficult-to-treat form of ovarian cancer

Research shows how dietary essential fatty acids can help treat Alzheimer’s, other diseases

Scientists gain new insights into protein network that regulates programmed cell death

Using AFM to study cell mechanics and function

Investigating new cancer therapy candidates with live-cell imaging

Freezing Point Osmometry in Life Science Applications

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