Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

UCR receives $2.2 million grant to target critical oncogenes of B-cell lymphoma 2

One way to tackle cancer, the second-leading cause of death in the United States, is to target oncogenes -- genes that have the potential to cause cancer.

17 Jan 2020

Study sets the record straight on unproven therapy to treat sepsis

The Jan. 17 issue of the Journal of the American Medical Association features an important study about sepsis with an accompanying editorial by a University of Nebraska Medical Center expert.

17 Jan 2020

Scientists discover how B-cells in tumor cells promote a favorable immunotherapy response

The white blood cells are potent fighters that protect the body against foreign invaders, including pathogens and cancer cells. Scientists have found that the presence of B cells, which are powerhouses, in tumor cells, combat the disease from within.

16 Jan 2020

Researchers identify how marijuana accelerates growth of HPV-related head and neck cancer

University of California San Diego School of Medicine researchers have identified the molecular mechanism activated by the presence of tetrahydrocannabinol (THC) - the ingredient that causes people to feel the euphoria or "high" associated with cannabis - in the bloodstream that accelerates cancer growth in patients with human papillomavirus (HPV)-positive head and neck squamous cell carcinoma.

13 Jan 2020

Scientists discover how dying cells prevent dangerous immune reactions

Dying cells in the body can keep the immune system in check, thus preventing unwanted immune responses against the body's own tissues.

8 Jan 2020

Daily aspirin use may help prevent colorectal cancer

A new study has shown that regular use of aspirin may protect against heart disease, reduce colorectal tumor growth and prevent relapse.

7 Jan 2020

Discovery of cellular 'hands' could have implications in the fields of cell, developmental biology

The protein, called syndecan-4, combines with fellow cell membrane proteins, called integrins, to form protruding 'hands' that sense the environment outside the cell.

6 Jan 2020

Aspirin’s benefits may extend beyond heart health to colorectal cancer treatment

The benefits of a daily aspirin may extend beyond heart health to colorectal cancer treatment, say City of Hope researchers who have found aspirin appears to reduce tumor growth and inhibit recurrence of the disease.

6 Jan 2020

Certain bacteria can override programmed cell death

Certain bacteria can override a defense mechanism of the immune system, so called programmed cell death, through inhibition of death effector molecules by their outer membranes components.

26 Dec 2019

Immunologists discover new RIPK1 mechanism that leads to cell death

Scientists at St. Jude Children's Research Hospital have discovered a new way that the molecule RIPK1 leads to cell death in infected, damaged or unwanted cells showing that more than one mechanism can trigger the process.

23 Dec 2019

p53 may play a more important role in kidney cancer than previously thought

The p53 gene, which researchers had thought was less relevant in kidney cancer, may play an important role after all – a discovery that could lead to new treatments.

20 Dec 2019

Catastrophic macropinocytosis may aid in cancer treatment

In laboratory experiments, a metabolic inhibitor was able to kill a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues through a non-apoptotic route -- catastrophic macropinocytosis.

18 Dec 2019

Novel and targeted cellular product causes cell death in non-Hodgkin lymphoma models

Investigators at Rutgers Cancer Institute of New Jersey have found that a treatment based on a novel cellular product programmed to deliver an overabundance of chimeric antigen receptor causes cell death in non-Hodgkin lymphoma models that are sensitive or resistant to standard therapies.

16 Dec 2019

New tool gives more reliable and precise results in cancer research

Every cell contains a vast number of proteins, each of which has a specific function, for example as a receptor for another molecule or an enzyme that catalyzes chemical reactions.

16 Dec 2019

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often prescribed to lower cholesterol, block this metabolic pathway and cause the cancer cells to die, as scientists from the German Cancer Research Center have now discovered.

12 Dec 2019

Apoptosis News and Research

UCR receives $2.2 million grant to target critical oncogenes of B-cell lymphoma 2

Study sets the record straight on unproven therapy to treat sepsis

Scientists discover how B-cells in tumor cells promote a favorable immunotherapy response

Researchers identify how marijuana accelerates growth of HPV-related head and neck cancer

Scientists discover how dying cells prevent dangerous immune reactions

Daily aspirin use may help prevent colorectal cancer

Discovery of cellular 'hands' could have implications in the fields of cell, developmental biology

Aspirin’s benefits may extend beyond heart health to colorectal cancer treatment

Certain bacteria can override programmed cell death

Immunologists discover new RIPK1 mechanism that leads to cell death

p53 may play a more important role in kidney cancer than previously thought

Catastrophic macropinocytosis may aid in cancer treatment

Novel and targeted cellular product causes cell death in non-Hodgkin lymphoma models

New tool gives more reliable and precise results in cancer research

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Researchers investigate NOTCH1 mutations in keratinocyte lines derived from OSCC biopsies

Scientist earns prestigious award for research into cell suicide

Failure in proteasome transportation system may cause neurodegenerative diseases

Streamlining Immuno-Oncological Therapeutic Antibody Discovery

Research findings provide novel therapeutic space to induce scarless regenerative healing

Applying Optical Filters to Neuroscience

How SpatialOMx is Delivering New Insights into Disease Research

Studying Alzheimer’s and Parkinson’s Disease using Pre-Formed Fibrils

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