Artemisinin News and Research

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Artemisinin is a drug used to treat multi-drug resistant strains of falciparum malaria. The compound (a sesquiterpene lactone) is isolated from the plant Artemisia annua. Not all plants of this species contain artemisinin.

Acute malnutrition raises risk of malaria treatment failure in young children

Children with acute malnutrition across Africa and Asia have a higher risk of treatment failure and malaria reinfection, even after being given the best currently available and recommended malaria treatment.

13 Mar 2024

What natural compounds can help you manage your rosacea?

Researchers reviewed existing data on rosacea management using botanicals.

7 Feb 2024

Deep learning algorithm identifies antimalarial drug as promising treatment for osteoporosis

Artificial intelligence has exploded in popularity and is being harnessed by some scientists to predict which molecules could treat illnesses, or to quickly screen existing medicines for new applications.

18 Oct 2023

New artemisinin-resistant malaria parasite detected in Eritrea

Diagnosis of Plasmodium falciparum malaria using rapid diagnostic tests and treatment with artemisinin derivatives, the main component of the malaria treatments recommended by the World Health Organization (WHO), are under threat in the Horn of Africa.

29 Sep 2023

Study demonstrates novel role of Axin1 in mediating intestinal homeostasis and microbiota

A groundbreaking study conducted by Jun Sun's research team at the University of Illinois Chicago has revealed a new and critical role of Axin1 in regulating intestinal epithelial development and microbial homeostasis.

22 Sep 2023

Scientists identify malaria-causing parasites resistant to both treatment and detection in Ethiopia

Scientists have detected new strains of malaria-causing parasites in Ethiopia that are both resistant to current treatments and escape detection by common diagnostic tests -; a development that could increase cases and deaths from malaria and make eliminating the persistent disease an even greater challenge.

11 Sep 2023

UTSA researchers study the mechanism of action of Sweet Annie's medicinal compounds

Vibrant green leaves sprout from tall fragrant plants sitting neatly in two rows of terracotta pots in Valerie Sponsel's UTSA biology laboratory.

8 Sep 2023

Researchers zero in on a potential new target for malaria: Biological clocks

Health officials warn that drug resistance could wipe out recent progress against malaria, particularly in Africa and southeast Asia.

6 Jun 2023

Novel way of synthesizing artemisinin could lead to cost-effective treatment for malaria

Southwest Research Institute (SwRI) and The University of Texas at San Antonio (UTSA) have developed a method to synthesize the highly potent antimalarial drug artemisinin, which could lead to a more cost-effective treatment for malaria.

2 May 2023

Laos malaria outbreak in 2020–21 likely caused by multidrug-resistant strains of P. falciparum

Researchers describe the genetic epidemiology and dynamics of the Plasmodium falciparum responsible for malaria outbreaks in Attapeu Province, Laos.

5 Dec 2022

Meta-analysis informs a change to treatment guidelines for uncomplicated malaria in the first trimester of pregnancy

A new WWARN meta-analysis commissioned by the World Health Organization (WHO) which informed a change to its treatment guidelines has been published in The Lancet.

28 Nov 2022

Researchers discover new antiviral compounds derived from two Korean native plants

Codonopsis lanceolata, more commonly referred to as "deodeok", is used as a medicinal herb in South Korea.

11 Nov 2022

Scientists create a mathematical model to predict genetic resistance to antimalarial drugs

Researchers have created a mathematical model to predict genetic resistance to antimalarial drugs in Africa to manage one of the biggest threats to global malarial control.

12 Aug 2022

The effect of Artemisia annua hot water extracts against the SARS-CoV-2 Omicron variant

Researchers assessed the effect of Artemisia annua hot water extracts against the SARS-CoV-2 Omicron variant.

28 Jul 2022

Researchers evaluate artemisinin for COVID-19 management

Researchers assessed the effectiveness of artemisinin-based antimalarials in the management of COVID-19.

16 Jun 2022

Well-established group of antimalarials unlikely to be affected by resistance, study shows

New research published today in Antimicrobial Agents and Chemotherapy, shows that the well-established group of antimalarials, known as artemisinins, are unlikely to be affected by resistance.

26 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Researchers at the University of California, San Francisco, have discovered that cells carrying the most common mutation found in human cancer accumulate large amounts of ferrous iron and that this "ferroaddiction" can be exploited to specifically deliver powerful anticancer drugs without harming normal, healthy cells.

11 Mar 2022

IPD pooled analysis quantifies the underlying hematological response following malaria infection

A new malaria study using a very large analysis of pooled individual patient data (IPD) from more than 70,000 patients of all ages, has been published today in BMC Medicine.

9 Mar 2022

Outcomes of phase 3 clinical trial of CVO PLUS CURATIF capsules for COVID-19 treatment

A phase 3 randomized clinical trial has recently been conducted to investigate the efficacy of a capsule formulation in treating mild-to-moderate COVID-19 patients.

23 Feb 2022