Aspergillosis News and Research

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Nearly 5 million asthmatics with ABPA could benefit from antifungal treatment, say researchers

An estimated 4,837,000 asthmatics with allergic bronchopulmonary aspergillosis (ABPA) could benefit substantially from antifungal treatment, say researchers from the University of Toronto and Manchester University.

9 May 2013

ICU misdiagnosis alarmingly common in the acute care setting

Each year as many as 40,500 critically ill U.S. hospital patients die with an unknown medical condition that may have caused or contributed to their death, Johns Hopkins patient safety experts report in a recent study.

28 Aug 2012

University of Nevada researcher to optimize new rapid test for melioidosis

A new rapid test to diagnose melioidosis, a difficult infection to treat - and classified as a biothreat by the Centers for Disease Control and Prevention - is being optimized and tested by University of Nevada School of Medicine researcher David AuCoin.

9 Aug 2012

Mylan receives FDA approval for generic Sporanox ANDA

Mylan Inc. today announced that its subsidiary Mylan Pharmaceuticals Inc. has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Itraconazole Capsules, 100 mg.

27 Jul 2012

Doctors underestimate worldwide burden of CPA, says public health expert

Researchers have discovered that over a million people worldwide diagnosed with TB go on to develop an incurable but manageable fungal infection which is usually left untreated because it is mistaken for a recurrence of the disease.

2 Dec 2011

Pfizer releases Phase III study results comparing VFEND-ERAXIS combination to VFEND for IA

Pfizer Inc. today reported the top-line results of an international Phase III clinical trial which compared the combination of VFEND (voriconazole) and ERAXISTM (anidulafungin) to VFEND monotherapy for primary therapy of invasive aspergillosis, a life-threatening invasive fungal infection that can develop as a complication in patients with compromised immune systems.

1 Oct 2011

Researchers discover lack of oxygen in the lungs after mold invasion

Researchers led by Montana State University have found a surprising condition that occurs in the lungs after an invasion of a common mold that can cause deadly infections in humans.

6 Aug 2011

Genome Research publishes studies utilizing emerging Collaborative Cross mouse strains

The Collaborative Cross represents a large collection of new inbred mouse strains created by the mouse genetics community aimed at revolutionizing the study of complex genetic traits and diseases. Derived from classical inbred strains and wild-derived strains, the CC captures nearly 90% of known genetic variation in laboratory mice, far surpassing more commonly used inbred strains.

15 Jul 2011

Lab21 acquires molecular diagnostics company Myconostica Ltd

Lab21 Limited, the global specialist in personalised medicine and clinical diagnostics has today announced that it has acquired Myconostica Ltd, a molecular diagnostic company focussing on the diagnosis of fungal infections of clinical importance.

23 May 2011

New test can diagnose deadly human fungal infections

Deadly human fungal infections caused by certain strains of Aspergillus fungi appear to be developing resistance to current drug treatments at an alarming rate, say scientists.

5 May 2011

Performance of Myconostica's MycAssay Aspergillus in CF reported at British Thoracic Society meeting

At the prestigious annual British Thoracic Society meeting in London on December 1st, Dr Caroline Baxter reported the highly sensitive performance of Myconostica's real-time PCR assay MycAssayTM Aspergillus in cystic fibrosis sputum which is 260% more sensitive than the currently used culture.

6 Dec 2010

Vitamin D may be effective in preventing allergies in patients cystic fibrosis, asthma

Vitamin D may be an effective therapy to treat and even prevent allergy to a common mold that can cause severe complications for patients with cystic fibrosis and asthma.

26 Aug 2010

Researchers discover a fungal protein that causes disease in plants and animals

Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech and Montana State University have discovered a fungal protein that plays a key role in causing disease in plants and animals and which also shields the pathogen from oxidative stress.

7 Nov 2009

Cimzia approved in U.S. for rheumatoid arthritis

UCB announced today that the U.S. Food and Drug Administration (FDA) approved Cimzia, the only PEGylated anti-TNF (Tumor Necrosis Factor), for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA).

13 May 2009

New test for a deadly fungal infection in patients with damaged immune systems

A quicker, cheaper and more accurate test for deadly Aspergillus fumigatus fungal infections in patients with damaged or suppressed immune systems was described today, (Thursday 2 April) at the Society for General Microbiology meeting in Harrogate, by Dr Christopher Thornton from the University of Exeter, UK.

1 Apr 2009

Discovery of gene that regulates mold's resistance to drugs

Montana State University scientists concerned about lethal mold infections have found a gene that regulates the mold's resistance to drugs.

8 Nov 2008

Gamma interferon could aid fight against fungal infections

Interferon, the "superhero" cure for viral infections, may be a strong weapon in the battle against fungal infections in immunocompromised patients, according to an article in the November issue of Microbiology Today.

1 Nov 2007

New treatment Candida fungi - fewer side effects

A new treatment for Candida species of fungi which can cause thrush and sepsis (a life-threatening infection leading to fever, hypotension, and shock) has proven equally effective as the existing treatment in a drug trial.

26 Apr 2007

LaeA gene shown to be an ideal prospect for new ways to fight infection

For the growing number of people with diminished immune systems - cancer patients, transplant recipients, those with HIV/AIDS - infection by a ubiquitous mold known as Aspergillus fumigatus can be a death sentence.

15 Apr 2007

New drug delivery method incorporates drug molecules in fat

Devastating blood-borne fungal infections that can be lethal for HIV/AIDS, cancer, and organ transplant patients may be treated more successfully, thanks to a new drug delivery method developed by researchers at the University of British Columbia in Vancouver.

5 Mar 2007