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New nanobiosensor can help diagnose early-stage multiple sclerosis

Researchers at the Federal University of São Carlos in Sorocaba have developed a technique to diagnose early-stage multiple sclerosis, a disease of the central nervous system, and distinguish it from neuromyelitis optica, a rare yet severe autoimmune inflammatory process also affecting the central nervous system.

23 Apr 2020

Chinese scientists develop two novel compounds that inhibit SARS-CoV-2 main protease

A team of Chinese scientists has recently developed two novel compounds that inhibit the SARS-CoV-2 main protease (Mpro) and one of them is a good drug candidate for further clinical studies.

23 Apr 2020

Study creates a new platform to study single-cell genomics of many diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

22 Apr 2020

Accelerating Antibody Discovery with Next-Generation Single-Cell Analysis

Accelerating antibody discovery using picodroplet technology for single cell analysis to condense discovery times down to 1-2 days.

From Sphere Fluidics 22 Apr 2020

P-BEST: Fast efficient COVID-19 virus testing before symptoms appear

A highly promising new study published on the preprint server medRxiv in April 2020 reports an efficient new method to conduct high-throughput testing of blood samples for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is causing the rapidly spreading pandemic of COVID-19 disease throughout the world. The method could revolutionize the diagnosis of new cases before they become symptomatic.

22 Apr 2020

PiCoVacc vaccine candidate for COVID-19 effective in animal trials

In a new study available on the bioRxiv preprint server, a group of researchers from China report on the pilot-scale production of a purified inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus vaccine candidate (PiCoVacc), shown to induce virus-specific neutralizing antibodies in rats, mice, and non-human primates.

21 Apr 2020

Sino Biological Partners with Nanommune Inc. to Develop and Market a Novel Coronavirus Multiplex Serological Assay

Sino Biological, Inc. today announced a co-development agreement with Nanommune Inc., an Irvine, California based biotechnology company specializing in the development and application of multiplex array technology.

From Sino Biological Inc. 21 Apr 2020

Bio-Rad Introduces Anti-Ipilimumab Antibodies

Bio-Rad Laboratories, Inc has extended its range of recombinant monoclonal anti-idiotypic antibodies.

21 Apr 2020

ACE2 receptor expression by SARS-CoV-2 across different animal species

A new report published on the preprint server bioRxiv in April 2020 reports that several species of animals can be infected with relative ease by the SARS-CoV-2 virus that is the causative agent of the currently raging COVID-19 pandemic. This casts much light on the possible natural hosts and routes of transmission of this virus.

20 Apr 2020

Mutations in novel coronavirus make it more dangerous

A new report published on the preprint server medRxiv in April 2020 reveals that the novel coronavirus SARS-CoV-2 shows the presence of new mutations acquired within infected human cases, which significantly increase its ability to cause human disease.

20 Apr 2020

CRISPR technology mobilized for rapid COVID-19 diagnosis

A group of authors from the United States published a study in the scientific journal Nature Biotechnology in which they have described a CRISPR-Cas-based approach for rapid and accurate diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection – without the need for complex laboratory infrastructure.

20 Apr 2020

A novel method for predicting promising antiviral drug or vaccine targets

A novel method to predict the most promising targets for antiviral drugs or vaccines is based on the conformational changes viral glycoproteins go through during the process of recognition and binding to the host cell.

20 Apr 2020

Study adds increasing evidence that autoimmunity plays a role in Parkinson's disease

A new study co-led by scientists at the La Jolla Institute for Immunology adds increasing evidence that Parkinson's disease is partly an autoimmune disease. In fact, the researchers report that signs of autoimmunity can appear in Parkinson's disease patients years before their official diagnosis.

20 Apr 2020

New high-throughput approach yields libraries of probes for immunological assays

An immunological test known as a "tetramer assay" can detect T cells in a blood sample that recognize a specific antigen.

20 Apr 2020

New research gives further evidence that autoimmunity plays a role in Parkinson's disease

A new study adds increasing evidence that Parkinson's disease is partly an autoimmune disease.

20 Apr 2020

Research suggests Nelfinavir and Cepharanthine as potential anti-SARS-CoV-2 agents

A new study published in the journal bioRxiv in April 2020 reports the identification of a promising multidrug treatment against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for causing COVID-19 disease. The team predicts that this combination will prevent the virus from reproducing, hence both halting the transmission and progress of the disease.

19 Apr 2020

Kehn-Hall working to rapidly test, deploy new tool to enhance detection of SARS-CoV-2

Kylene Kehn-Hall, Associate Professor/Associate Director, School of Systems Biology, National Center for Biodefense and Infectious Diseases, is working to rapidly test and deploy a universal virus enrichment tool that can be used to enhance the detection of SARS-CoV-2 (COVID-19) for any type of diagnostic assay under development, thereby reducing false negatives and the risk of worldwide pandemic.

18 Apr 2020

Horizon Discovery offers rapid access to CHOSOURCE platform for development of COVID-19 therapies

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation for cell line engineering, today announced special commercial licensing terms to facilitate rapid access to its cGMP-compliant CHOSOURCE platform for the development or production of therapeutic proteins, diagnostic assay components or vaccines relating to COVID-19.

16 Apr 2020

FDA grants Emergency Use Authorization to Ortho’s COVID-19 total antibody test

The U.S. Food and Drug Administration today announced it granted Emergency Use Authorization to Ortho Clinical Diagnostics' total antibody assay for COVID-19—the VITROS Immunodiagnostic Products Anti-SARS-CoV-2 Total Reagent Pack and Calibrators.

From Ortho-Clinical Diagnostics, Inc. 16 Apr 2020

Researchers develop a faster, more accurate COVID-19 test

Millions of people have been tested for the novel coronavirus, most using a kit that relies on the polymerase chain reaction.

15 Apr 2020

Assay News and Research

New nanobiosensor can help diagnose early-stage multiple sclerosis

Chinese scientists develop two novel compounds that inhibit SARS-CoV-2 main protease

Study creates a new platform to study single-cell genomics of many diseases

Accelerating Antibody Discovery with Next-Generation Single-Cell Analysis

P-BEST: Fast efficient COVID-19 virus testing before symptoms appear

PiCoVacc vaccine candidate for COVID-19 effective in animal trials

Sino Biological Partners with Nanommune Inc. to Develop and Market a Novel Coronavirus Multiplex Serological Assay

Bio-Rad Introduces Anti-Ipilimumab Antibodies

ACE2 receptor expression by SARS-CoV-2 across different animal species

Mutations in novel coronavirus make it more dangerous

CRISPR technology mobilized for rapid COVID-19 diagnosis

A novel method for predicting promising antiviral drug or vaccine targets

Study adds increasing evidence that autoimmunity plays a role in Parkinson's disease

New high-throughput approach yields libraries of probes for immunological assays

New research gives further evidence that autoimmunity plays a role in Parkinson's disease

Research suggests Nelfinavir and Cepharanthine as potential anti-SARS-CoV-2 agents

Kehn-Hall working to rapidly test, deploy new tool to enhance detection of SARS-CoV-2

Horizon Discovery offers rapid access to CHOSOURCE platform for development of COVID-19 therapies

FDA grants Emergency Use Authorization to Ortho’s COVID-19 total antibody test

Researchers develop a faster, more accurate COVID-19 test

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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