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FDA approves first drug for treatment of adult AML patients with specific genetic mutation

The U.S. Food and Drug Administration today approved Tibsovo (ivosidenib) tablets for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) who have a specific genetic mutation.

20 Jul 2018

Karius Test accurately detects invasive fungal infections, shows study

Karius, a life sciences company transforming infectious disease diagnostics with genomics and data through the innovative use of next-generation sequencing to analyze microbial cell-free DNA, announced today the positive results of a clinical study using blood samples from patients with confirmed invasive fungal infections.

20 Jul 2018

Homogenous BTK occupancy assay used in tirabrutinib clinical studies

In a new SLAS Discovery article, Helen Yu and a team of researchers at Gilead Sciences, Inc. present a time-resolved fluorescence resonance energy transfer-based Bruton's tyrosine kinase occupancy assay that can measure target engagement in peripheral blood mononuclear cells and in lymph-node and bone-marrow samples.

17 Jul 2018

Fruit fly research leads to potential drug for debilitating diseases caused by parasitic worms

River blindness and elephantiasis are debilitating diseases caused by parasitic worms that infect as many as 150 million people worldwide.

13 Jul 2018

Engineer patents cost-effective method to remove endotoxins from fluids

By some estimates, 18 million people die each year from sepsis triggered by endotoxins – fragments of the outer membranes of bacteria.

13 Jul 2018

New study suggests testing urine and blood serum as better way to diagnose myeloma

When it comes to diagnosing a condition in which the plasma cells that normally make antibodies to protect us instead become cancerous, it may be better to look at the urine as well as the serum of our blood for answers, pathologists say.

13 Jul 2018

Researchers attempt to create better diagnostic test for radiation exposure

Researchers at the University of Arizona College of Medicine - Phoenix are attempting to create a better diagnostic test for radiation exposure that potentially could save thousands of lives.

11 Jul 2018

Scientists discover new way to predict healthy individuals at risk of developing AML

An international team of leukemia scientists has discovered how to predict healthy individuals at risk of developing acute myeloid leukemia, an aggressive and often deadly blood cancer.

10 Jul 2018

Vitamin D assay from CLC paves way for disease diagnosis

The EZ Vitamin D assay is intended for use in clinical laboratories for the quantitative determination of 25-OH vitamin D in human plasma.

From Carolina Liquid Chemistries Corp. 9 Jul 2018

New study reveals potential shortcomings of antibiotic susceptibility assays

To determine which antibiotics reliably treat which bacterial infections, diagnostic laboratories that focus on clinical microbiology test pathogens isolated from patients.

9 Jul 2018

New small molecules offer promising new way to treat autoinflammatory diseases

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory diseases.

4 Jul 2018

Candida Auris testing kit for use in hospital hygiene applications announced by Bruker

At the International Society for Human and Animal Mycology meeting, Bruker announces Fungiplex™ Candida Auris, a new research-use-only, real-time PCR assay and kit for the detection of Candida auris in hospital hygiene applications.

From Bruker Life Sciences Mass Spectrometry 4 Jul 2018

Simple, accurate and reproducible assay to measure antibodies against malaria

Antibodies against multiple Plasmodium falciparum proteins (or antigens) can be measured using a simple, accurate and reproducible assay that requires very small amounts of blood.

3 Jul 2018

New Rekovelle analysis shows AMH is robust predictor of ovarian response to fertility treatment

Ferring Pharmaceuticals announced today a new analysis of data from the Phase 3 ESTHER-1 trial showing that natural variations in anti-Müllerian hormone levels during and between a woman's menstrual cycle have no clinically relevant impact on ovarian response when using AMH to dose Rekovelle for ovarian stimulation.

2 Jul 2018

Bruker introduces innovative Sierra SPR-32 system at European SLAS 2018 meeting

At the European SLAS 2018 meeting, Bruker today announced the launch of its new SierraTM SPR-32 system with even higher sensitivity and new instrument control software to enable highest SPR throughput with outstanding sensitivity.

From Bruker Life Sciences Mass Spectrometry 29 Jun 2018

Distek’s PrepEngine Mini speeds up sample preparation by 90%

Distek Inc. is excited to release the PrepEngine Mini Sample Prep Station for assay, impurity and content uniformity applications.

26 Jun 2018

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Pancreatic cancer is lethal in about 95% of cases mostly due to failure of first-line therapy gemcitabine. AntiCancer Inc.'s oral methioninase (AC 00619), which is in late pre-clinical development as an anti-cancer as well as an anti-aging drug, has now been shown to overcome gemcitabine resistance in mouse models of human pancreatic cancer, including AntiCancer's patient-derived orthotopic xenograft mouse models.

25 Jun 2018

UC Riverside researcher receives grants to advance cancer, ALS research

Maurizio Pellecchia, who holds the Daniel Hays Chair in Cancer Research at the University of California, Riverside, has received two grants to continue his research aimed at finding therapeutics for cancer, amyotrophic lateral sclerosis, and other neurodegenerative diseases.

21 Jun 2018

KIYATEC enrolls first patients with solid tumors in clinical study of its EV3D drug response assay

KIYATEC, Inc. today announced the enrollment of the first patients in a U.S. clinical study of its Ex Vivo 3D drug response assay across several difficult-to-treat solid tumors.

20 Jun 2018

Improving the quality of biomedical research samples

IBBL (Integrated BioBank of Luxembourg) announces the launch of Findmyassay.com, a new online tool allowing scientists to check the quality of their biological samples and improve the reproducibility of their biomedical research.

19 Jun 2018

Assay News and Research

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

Karius Test accurately detects invasive fungal infections, shows study

Homogenous BTK occupancy assay used in tirabrutinib clinical studies

Fruit fly research leads to potential drug for debilitating diseases caused by parasitic worms

Engineer patents cost-effective method to remove endotoxins from fluids

New study suggests testing urine and blood serum as better way to diagnose myeloma

Researchers attempt to create better diagnostic test for radiation exposure

Scientists discover new way to predict healthy individuals at risk of developing AML

Vitamin D assay from CLC paves way for disease diagnosis

New study reveals potential shortcomings of antibiotic susceptibility assays

New small molecules offer promising new way to treat autoinflammatory diseases

Candida Auris testing kit for use in hospital hygiene applications announced by Bruker

Simple, accurate and reproducible assay to measure antibodies against malaria

New Rekovelle analysis shows AMH is robust predictor of ovarian response to fertility treatment

Bruker introduces innovative Sierra SPR-32 system at European SLAS 2018 meeting

Distek’s PrepEngine Mini speeds up sample preparation by 90%

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

UC Riverside researcher receives grants to advance cancer, ALS research

KIYATEC enrolls first patients with solid tumors in clinical study of its EV3D drug response assay

Improving the quality of biomedical research samples

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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