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Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, has presented new prospective data demonstrating the strong impact of its 70-Gene Breast Cancer Recurrence assay, MammaPrint, and the corresponding 80-Gene Molecular Subtyping Assay BluePrint, in clinical decision-making for patients with early-stage breast cancer in Germany.

22 Dec 2016

New detection method could lead to noninvasive diagnosis of Creutzfeldt-Jakob disease

The detection of prions in the blood of patients with variant Creutzfeldt-Jakob disease could lead to a noninvasive diagnosis prior to symptoms and a way to identify prion contamination of the donated blood supply, according to researchers at McGovern Medical School at The University of Texas Health Science Center at Houston.

22 Dec 2016

Chromatrap® ensures best quality chromatin in ChIP assays

Chromatrap® offers an optimised unique buffer chemistry that provides the leading solution for the isolation of high quality and high yield chromatin. The success of any ChIP assay is dependent upon the quality of your chromatin.

From Chromatrap® - Porvair Sciences Ltd 20 Dec 2016

New ultrasensitive detection system of in-flow microRNAs uses encoded microgels

Single-stranded, noncoding micro-ribonucleic acids, consisting of 18-23 nucleotides, play a key role in regulating gene expression.

19 Dec 2016

Portable detection system can rapidly identify virulent, multi-drug resistant pathogens in remote areas

A team of researchers has developed a portable detection system that can rapidly identify some of the most virulent, often multi-drug resistant pathogens.

16 Dec 2016

Mayo Clinic creates genetic test to help guide diagnosis, treatment of lymphoma patients

Mayo Clinic has created a genetic test to help guide diagnosis and treatment of patients with diffuse large B-cell lymphoma, the most common type of non-Hodgkin's lymphoma.

16 Dec 2016

Lab-based cellular tests reveal that e-cigarette vapour does not induce DNA damage

E-cigarette vapour does not damage DNA, even at doses 28 times that of equivalent smoke exposure.

16 Dec 2016

Newborns with CMV may have increased risk of developing acute lymphocytic leukemia

Newborns with congenital cytomegalovirus (CMV) -- a common virus in the herpes family -- may have an increased risk of developing acute lymphocytic leukemia (ALL), according to new research published online today in Blood, the Journal of the American Society of Hematology. The study suggests the risk is even greater in Hispanic children.

15 Dec 2016

Porvair sciences introduce products for use in animal and plant genetics

Porvair Sciences will showcase two important technical breakthroughs at PAG XXV in San Diego (USA) from January 14-18, 2017.

From Chromatrap® - Porvair Sciences Ltd 15 Dec 2016

BBI Solutions announces launch of Porcine Liver Esterase enzyme for Urinalysis

BBI Solutions today announced the launch of Porcine Liver Esterase (PLE), a new enzyme for Urinalysis, which is available to sample now.

14 Dec 2016

EUCAST experts say that genetic testing methods cannot be used to determine antimicrobial susceptibility

Experts at the European Committee on Antimicrobial Susceptibility Testing, who define the optimal drug concentrations to inhibit the growth of pathogens, have found that genetic methods cannot yet be used to test for susceptibility in a number of important bacterial species.

9 Dec 2016

Duke researchers develop new cell-based drug screening test for dystonia

Duke University researchers have identified a common mechanism underlying separate forms of dystonia, a family of brain disorders that cause involuntary, debilitating and often painful movements, including twists and turns of different parts of the body.

8 Dec 2016

AstraZeneca introduces world’s most advanced drug discovery robot

AstraZeneca entered a new era in drug development today by unveiling NiCoLA-B, the world’s most advanced drug discovery robot, capable of performing experiments at an industrial scale in the search for new, life-saving medicines.

8 Dec 2016

PITX2 methylation biomarker shows promise for predicting prostate cancer recurrence risk

Prostate-specific antigen (PSA) and other biomarkers are essential tools for diagnosing and monitoring prostate cancer.

8 Dec 2016

New discovery paves way to development of biochemical test for diagnosing Parkinson's disease

Misfolded proteins associated with Parkinson's disease were detected in cerebrospinal fluid by scientists at McGovern Medical School at The University of Texas Health Science Center at Houston, paving the way to development of a biochemical test to diagnosis the disease.

7 Dec 2016

Detecting inflammation in diabetic patients

As well as presenting with high blood glucose, diabetic patients have chronic low-grade inflammation, which can be measured by a range of inflammatory markers such as so-called high-sensitive CRP, TNFa and IL-6 as well as a full blood cell count.

7 Dec 2016

Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

Osaka University researchers revealed that the metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial-mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread.

1 Dec 2016

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity.

30 Nov 2016

New study to examine effectiveness of old antibiotic drug for treating gonorrhea infections

A new clinical research study seeks to determine whether a rapid molecular diagnostic test can reliably identify gonorrhea infections that may be successfully treated with a single dose of an older antibiotic, ciprofloxacin.

18 Nov 2016

Scientists reveal key details of the body's immune response to fungal infections

Every year, fungal infections threaten thousands of patients -- from those with depressed immune systems to others who have had surgeries or devices such as catheters implanted. Moreover, some anti-fungal medications are beginning to lose their power.

17 Nov 2016

Assay News and Research

Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

New detection method could lead to noninvasive diagnosis of Creutzfeldt-Jakob disease

Chromatrap® ensures best quality chromatin in ChIP assays

New ultrasensitive detection system of in-flow microRNAs uses encoded microgels

Portable detection system can rapidly identify virulent, multi-drug resistant pathogens in remote areas

Mayo Clinic creates genetic test to help guide diagnosis, treatment of lymphoma patients

Lab-based cellular tests reveal that e-cigarette vapour does not induce DNA damage

Newborns with CMV may have increased risk of developing acute lymphocytic leukemia

Porvair sciences introduce products for use in animal and plant genetics

BBI Solutions announces launch of Porcine Liver Esterase enzyme for Urinalysis

EUCAST experts say that genetic testing methods cannot be used to determine antimicrobial susceptibility

Duke researchers develop new cell-based drug screening test for dystonia

AstraZeneca introduces world’s most advanced drug discovery robot

PITX2 methylation biomarker shows promise for predicting prostate cancer recurrence risk

New discovery paves way to development of biochemical test for diagnosing Parkinson's disease

Detecting inflammation in diabetic patients

Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

New study to examine effectiveness of old antibiotic drug for treating gonorrhea infections

Scientists reveal key details of the body's immune response to fungal infections

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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