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New technique detects specific chromosomal damage - helps identify precancerous changes

A new technique could pave the way toward screening people at risk for lung cancer for the genetic changes that may foreshadow malignancies, researchers from the University of Colorado say.

3 Sep 2007

Geron demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction

Geron Corporation has reported its scientists and collaborators have demonstrated that human embryonic stem cell (hESC)-derived cardiomyocytes improve heart function when transplanted after myocardial infarction.

28 Aug 2007

Novel approach used to uncover genetic components of aging

People who live to 100 or more are known to have just as many - and sometimes even more - harmful gene variants compared with younger people.

26 Aug 2007

Reported failure of vitamin E to prevent heart attacks may be due to underdosing

The findings, published early online in Free Radical Biology and Medicine, suggest that these earlier studies all had a fundamental flaw the doses used werent high enough to have a significant antioxidant effect.

24 Aug 2007

Cell-based sensor for analysis of EGFR biomarker expression in oral cancer

Using a microfluidic device designed to capture and enrich cells from biological samples, a research team at The University of Texas at Austin has developed a test that can detect an important early marker for oral squamous cell carcinoma, which accounts for more than 90 percent of oral cancers. Oral cancer is the sixth most common cancer worldwide and is difficult to detect early enough to treat successfully.

22 Aug 2007

New diagnostic tool to detect infection-causing bacteria

Infection-causing bacteria can't hide from researchers at Northern Arizona University, who recently helped develop the first diagnostic tool to detect them.

3 Aug 2007

Researchers improve accuracy of thyroid hormone testing

Researchers at Georgetown University Medical Center have developed a fast and accurate way to measure a major hormone released by the thyroid gland--an advance they say may help in the treatment of many women who have overactive or underactive thyroid glands.

26 Jul 2007

Gold nanorods identify metastatic tumor cells

Using a series of gold nanorods, each with its own characteristic optical signature, researchers at Purdue University have developed a method for rapidly assaying the cellular composition of breast tumors.

23 Jul 2007

Nanoscale dots target and track apoptosis

Apoptosis, or programmed cell death, is a hallmark effect triggered by effective anticancer drugs. Now, researchers in Korea have developed a biocompatible, fluorescent nanoparticle that could provide an early sign that apoptosis is occurring as a result of anticancer therapy.

23 Jul 2007

Fast market penetration for Roche HIV viral load monitoring test

One-third of Roche Diagnostics' molecular customer base has already purchased or ordered the COBAS AmpliPrep /COBAS TaqMan HIV-1 assay, just eight weeks after the assay received approval from the Food & Drug Administration to go to market.

From Roche Sequencing and Life Science 17 Jul 2007

FDA approves gene test to detect spread of breast cancer into lymph nodes

Veridex, LLC, a Johnson & Johnson company, has announced U.S. Food and Drug Administration (FDA) approval of the first intra-operative and gene-based test to detect the spread of breast cancer into the lymph nodes.

17 Jul 2007

FDA approves new test which detects breast cancer spread

The Food and Drug Administration (FDA) in the U.S. has given approval for a new test to be used which can detect if breast cancer has spread to a patient's lymph nodes.

16 Jul 2007

Senomyx issued new U.S. patent for "T1R taste receptors and genes encoding same"

Senomyx, Inc. has announced the issuance by the U.S. Patent and Trademark Office of U.S. Patent No. 7,241, 880, "T1R Taste Receptors and Genes Encoding Same."

12 Jul 2007

Notch2 locus predicts prognosis in brain tumor patients

PLoS ONE has just published a study which defines a gene locus on chromosome 1 that predicts prognosis of brain tumor patients and may even set the basis for the development of more efficient drugs to combat brain cancer.

28 Jun 2007

Why NSAIDs damage the tissue that lines the gastrointestinal tract

New versions of drugs like buffered aspirin and Vioxx could produce fewer harmful side effects thanks to research being done at Kansas State University's College of Veterinary Medicine.

23 Jun 2007

DNA repair proteins monitored at double-strand break

St. Jude investigators recently had a molecule's eye view of the human cell's DNA repair kit as it assembled on a double-strand break to link together the broken ends.

23 Jun 2007

Entecavir can compromise HIV treatment

Treating hepatitis B patients with the drug entecavir can cause those who are also infected with HIV to become resistant to two of the most important drugs in the anti-HIV arsenal, according to a new report in the New England Journal of Medicine.

23 Jun 2007

New uderstanding of how enzymes work

In a publication selected as a "2007 Hot Article" by the journal Biochemistry , University at Buffalo chemists report the discovery of a central mechanism responsible for the action of the powerful biological catalysts known as enzymes.

20 Jun 2007

Biomoda files patent protection for lung cancer detection technology

Biomoda, Inc. has disclosed that it is again expanding its intellectual property portfolio with an additional unique patent pending to enhance the stability and greatly increase the shelf-life of its assay.

17 Jun 2007

CRT and Manchester University announce biomarker alliance with AstraZeneca

Cancer Research Technology Limited (CRT), the cancer-focused development and commercialisation company, and The University of Manchester today announce the establishment of an alliance with AstraZeneca to develop serological pharmacodynamic (PD) biomarkers.

4 Jun 2007

Assay News and Research

New technique detects specific chromosomal damage - helps identify precancerous changes

Geron demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction

Novel approach used to uncover genetic components of aging

Reported failure of vitamin E to prevent heart attacks may be due to underdosing

Cell-based sensor for analysis of EGFR biomarker expression in oral cancer

New diagnostic tool to detect infection-causing bacteria

Researchers improve accuracy of thyroid hormone testing

Gold nanorods identify metastatic tumor cells

Nanoscale dots target and track apoptosis

Fast market penetration for Roche HIV viral load monitoring test

FDA approves gene test to detect spread of breast cancer into lymph nodes

FDA approves new test which detects breast cancer spread

Senomyx issued new U.S. patent for "T1R taste receptors and genes encoding same"

Notch2 locus predicts prognosis in brain tumor patients

Why NSAIDs damage the tissue that lines the gastrointestinal tract

DNA repair proteins monitored at double-strand break

Entecavir can compromise HIV treatment

New uderstanding of how enzymes work

Biomoda files patent protection for lung cancer detection technology

CRT and Manchester University announce biomarker alliance with AstraZeneca

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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