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Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

An unexpected discovery made by experts at the Brain Tumor Center at Cincinnati Children's while studying a rare-but-deadly type of brain tumor may also lead to improved treatments for several other forms of cancer that share a common influencing factor called a YAP fusion protein.

2 Feb 2023

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Patients with glioblastoma-;the deadliest type of primary brain tumor-;may potentially benefit from immunotherapy medications called immune checkpoint inhibitors that stimulate an immune response against cancer cells.

2 Feb 2023

Study offers clues about the biology of cells in the spinal cord that die off in ALS

New research offers clues about the biology of cells in the spinal cord that die off in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.

2 Feb 2023

Adoption of electric cars associated with reductions in air pollution and respiratory problems

Electric vehicles are widely hailed as a key way to mitigate climate change through reduced emissions, but research on the dual benefits of reduced air pollution and improved health has been largely hypothetical.

2 Feb 2023

UC Davis launches new institute to advance basic knowledge of psychedelics and neurotherapeutics

The University of California, Davis has launched the Institute for Psychedelics and Neurotherapeutics to advance basic knowledge about the mechanisms of psychedelics and translate it into safe and effective treatments for diseases such as depression, post-traumatic stress disorder, addiction, Alzheimer's disease and Parkinson's disease, among others.

2 Feb 2023

Novel tool uses AI to predict the efficacy of genome-editing repair options

Researchers at the University of Zurich have developed a new tool that uses artificial intelligence to predict the efficacy of various genome-editing repair options.

2 Feb 2023

Bone marrow transplants may prevent blood vessel disease in patients with sickle cell disease

Bone marrow transplants prevented or improved blood vessel disease in the brains of adults with sickle cell disease, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Researchers identify a gene that drives T lymphocytes to exhaustion

A research group funded by the Swiss National Science Foundation has identified a gene that drives T lymphocytes to exhaustion. This opens up new approaches for more effective immunotherapies.

2 Feb 2023

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.

2 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

What is the incidence of COVID-19-associated febrile seizures in children?

Researchers investigated the incidence of febrile seizures among SARS-CoV-2-positive children.

2 Feb 2023

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Researchers evaluated the clinical and genetic characteristics of acute myeloid leukemia (AML) patients with a mutant Ikaros zinc finger protein 1 (IKZF1).

2 Feb 2023

Knowing your cholesterol level can be a crucial factor in overall health

On a top 10 list of things to do, getting your cholesterol level checked likely doesn't make the cut – but no matter your age, knowing your numbers can be a crucial factor in overall health.

2 Feb 2023

'Outside-the-box' method of teaching AI models opens the prospect of finding new cancer treatments

A new 'outside-the-box' method of teaching artificial intelligence (AI) models to make decisions could provide hope for finding new therapeutic methods for cancer, according to a new study from the University of Surrey.

1 Feb 2023

U of A researcher one step closer to demonstrating the potential of brain molecule to halt MS

A University of Alberta researcher is one step closer to demonstrating the potential of a brain molecule called fractalkine to halt and even reverse the effects of multiple sclerosis and other neurodegenerative diseases.

1 Feb 2023

Light-activated nanoscale drills can combat infectious fungi

That stubborn athlete's foot infection an estimated 70% of people get at some point in their life could become much easier to get rid of thanks to nanoscale drills activated by visible light.

1 Feb 2023

New optogenetic tool to study and modulate plasticity in the cerebellum

Light can trigger a signaling cascade in the cerebellum. This also illuminates processes that play an important role in cerebellar diseases.

1 Feb 2023

Highly effective detection of cancer biomarkers using CRISPR

Most cancer diagnostic techniques rely on uncomfortable and invasive procedures, such as biopsies, endoscopies or mammograms.

1 Feb 2023

MD Anderson and Federation Bio collaborate to design and manufacture a synthetic microbial consortium

The University of Texas MD Anderson Cancer Center and Federation Bio today announced a strategic collaboration to design and manufacture a complex, synthetic microbial consortium with the goal of expanding the number of cancer patients who respond to immunotherapy.

1 Feb 2023

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

A recent study posted on the bioRxiv* preprint server has longitudinally characterized the MBC repertoire and humoral response after Omicron BA.1 breakthrough infection in individuals vaccinated with the COVID-19 mRNA vaccine.

1 Feb 2023

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B Cell News and Research

Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Study offers clues about the biology of cells in the spinal cord that die off in ALS

Adoption of electric cars associated with reductions in air pollution and respiratory problems

UC Davis launches new institute to advance basic knowledge of psychedelics and neurotherapeutics

Novel tool uses AI to predict the efficacy of genome-editing repair options

Bone marrow transplants may prevent blood vessel disease in patients with sickle cell disease

Researchers identify a gene that drives T lymphocytes to exhaustion

Microscopic technique enables real-time study of RNA G-quadruplexes in living cells

Researchers report a heterologous vaccination strategy against IBV in Chickens

What is the incidence of COVID-19-associated febrile seizures in children?

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Knowing your cholesterol level can be a crucial factor in overall health

'Outside-the-box' method of teaching AI models opens the prospect of finding new cancer treatments

U of A researcher one step closer to demonstrating the potential of brain molecule to halt MS

Light-activated nanoscale drills can combat infectious fungi

New optogenetic tool to study and modulate plasticity in the cerebellum

Highly effective detection of cancer biomarkers using CRISPR

MD Anderson and Federation Bio collaborate to design and manufacture a synthetic microbial consortium

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

Immunology eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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