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New player in the control of HDL cholesterol

Researchers have identified a new player in the control of so-called "good" cholesterol that circulates in the bloodstream and reduces heart attack risk, according to a report in the August issue of Cell Metabolism, a publication of Cell Press.

8 Aug 2007

Bcl-3 protein regulates inflammation by blocking ubiquitination

Researchers at the University of Pennsylvania School of Medicine recently identified how a regulatory protein called Bcl-3 helps to control the body's inflammation response to infection by interfering a critical biochemical process called ubiquitination.

8 Aug 2007

High-intensity focused ultrasound may alerts the immune system to cancer

An intense form of ultrasound that shakes a tumor until its cells start to leak can trigger an alarm that enlists immune defenses against the cancerous invasion, according to a study led by researchers at Duke University's Pratt School of Engineering.

8 Aug 2007

Chemotherapy with bevacizumab increases risk of blood clots in arteries

Treatment with chemotherapy and bevacizumab, an anticancer drug, is associated with a greater risk of blood clots in patients, arteries compared with treatment with chemotherapy only, according to a study published online August 7 in the Journal of the National Cancer Institute.

8 Aug 2007

Bacteria - you can live without 'em, but it won't do you any good!

The finding challenges the conventional wisdom that even harmless bacteria – and the immune response they provoke – suck up the energy of the host organism and hasten its death.

8 Aug 2007

Scientists tackle gene doping in athletes

Gene doping has the potential to spawn athletes capable of out-running, out-jumping and out-cycling the strongest of champions.

7 Aug 2007

New research may lead to future gene therapies for patients with sickle cell anemia and beta-thalassemia

Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.

7 Aug 2007

Overexposure to metals and Alzheimer's disease

A multi-institutional team of researchers led by Emory University has defined for the first time how metal ions bind to amyloid fibrils in the brain in a way that appears toxic to neurons.

7 Aug 2007

New understanding of Leber congenital amaurosis

People suffering from a severe retinal disease will sooner or later lose their eyesight considerably or even become completely blind.

7 Aug 2007

Potential new ways to prevent smoking-related cellular damage

In the current issue of PLoS One, researchers show how a poorly understood and previously unsuspected mechanism may be the key to understanding how life-style associated forms of oxidative stress, such as exposure to cigarette smoke, damage cells in the lungs.

7 Aug 2007

Link identified between Alzheimer's disease and glaucoma

UK scientists have shown for the first time that key proteins involved in Alzheimer's disease are also implicated in glaucoma, the major cause of irreversible blindness worldwide.

7 Aug 2007

How cells change the pace of their steps

Scientists at UC San Diego have discovered how cells of higher organisms change the speed at which they move, a basic biological discovery that may help researchers devise ways to prevent cancer cells from spreading throughout the body.

7 Aug 2007

Green tea holds promise for psoriasis and dandruff

Green tea could hold promise as a new treatment for skin disorders such as psoriasis and dandruff, Medical College of Georgia researchers say.

7 Aug 2007

Mechanistic model of DNA repair

Ionizing radiation, toxic chemicals, and other agents continually damage the body's DNA, threatening life and health: unrepaired DNA can lead to mutations, which in turn can lead to diseases like cancer.

6 Aug 2007

New insight into mechanism of DNA-break repair

A new UC Davis study that explains the actions of a gene mutation that causes early onset cancer provides a fundamental insight into the mechanism of DNA-break repair.

6 Aug 2007

Ten ALS genes found

Blood samples from more than 220 ALS patients at the Methodist Neurological Institute were used in research that revealed significant changes in or around 10 specific genes in sporadic ALS, the most common form of ALS.

6 Aug 2007

LKB1 gene - new lung tumor-suppressor

Collaborating scientists in Boston and North Carolina have found that a particular gene can block key steps of the lung cancer process in mice.

6 Aug 2007

New tool for use in addressing lead poisoning

Lead in goat blood might not be on the top of your shopping list, but for U.S. medical personnel who each year perform more than 2 million human blood measurements, Standard Reference Material (SRM) 955c from the National Institute of Standards and Technology (NIST) can't be beat.

6 Aug 2007