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New collaborative model for drug discovery can ensure antibiotics are not lost to resistance

Noting "multidrug-resistant organisms are showing up in top-flight hospitals" around the world, Carl Nathan, chair of the department of microbiology and immunology at Weill Cornell Medical College, writes in this New York Times opinion piece, "What makes the rapid loss of antibiotics to drug resistance particularly alarming is that we are failing to make new ones."

12 Dec 2012

Researchers shed new light on how salmonella bacteria cause infections

Researchers have found that the bacteria are able to change key cells that line the intestine, enabling the bugs to thrive.

12 Dec 2012

Two UT Southwestern researchers to receive 2013 Edith and Peter O'Donnell Award

The Academy of Medicine, Engineering, and Science of Texas (TAMEST) announced that two UT Southwestern Medical Center researchers are among the four chosen for the 2013 Edith and Peter O'Donnell Awards.

12 Dec 2012

Clinical trial to examine AstraZeneca experimental drug against pulmonary tuberculosis

A clinical trial will examine an investigational drug's early bacteria-killing activity in patients newly diagnosed with drug-sensitive pulmonary tuberculosis.

12 Dec 2012

Bacteriophages may play an important role in competition among bacterial strains

Unique viruses called bacteriophages may play an important role in competition among bacterial strains, influencing the overall ecosystem of the human intestine, scientists at The University of Texas at Arlington and UT Southwestern Medical Center say.

11 Dec 2012

Top-line results from Durata Therapeutics’ dalbavancin Phase 3 study on ABSSSI

Durata Therapeutics, Inc. today announced preliminary, top-line results for its DISCOVER 1 ("Dalbavancin for Infections of the Skin COmpared to Vancomycin at an Early Response") Phase 3 study of dalbavancin, which is under investigation for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible gram-positive bacteria, including MRSA (methicillin resistant Staphylococcus aureus).

11 Dec 2012

Orientation of antibody binding to bacteria can mean life or death to the bug

The orientation of antibody binding to bacteria can mean life or death to the bug, according to a study published in The Journal of Experimental Medicine on December 10th. These findings may help explain why these bacteria cause millions of localized infections, but more serious, systemic blood infections are rare.

11 Dec 2012

Potential way to attack common stomach bacteria that cause ulcers

Experiments at the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory have revealed a potential new way to attack common stomach bacteria that cause ulcers and significantly increase the odds of developing stomach cancer.

10 Dec 2012

Communication and checklists may lead to fewer surgical complications

An article published in the December issue of the Journal of the American College of Surgery found decreases in some postoperative complications when surgical teams were trained in communication and to use a procedure check list.

10 Dec 2012

First Edition: December 10, 2012

Today's headlines include news about yesterday's "fiscal cliff" meeting between President Barack Obama and House Speaker John Boehner, as well as other health policy reports.

10 Dec 2012

BlueGenics aims to discover new drugs from deep sea to combat osteoporosis

Searching for substances from the deep sea to combat osteoporosis and other human common diseases is one of the objectives of the new European research project "BlueGenics" which has received funding of EUR 6 million from the European Commission.

10 Dec 2012

Researchers track emergence and global spread of healthcare-associated C. difficile

Researchers show that the global epidemic of Clostridium difficile 027/NAP1/BI in the early to mid-2000s was caused by the spread of two different but highly related strains of the bacterium rather than one as was previously thought. The spread and persistence of both epidemics were driven by the acquisition of resistance to a frontline antibiotic.

10 Dec 2012

Exposure to passive smoking may increase risk of invasive meningococcal disease in children

The dangers of second-hand smoke (passive smoking) on children continue to become ever more apparent. A new study published in BioMed Central's open access journal BMC Public Health shows that second hand smoke and foetal exposure due to maternal smoking while pregnant significantly increase the risk of invasive meningococcal disease.

10 Dec 2012

C5aRA treatment could be effective against periodontitis

Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In its most severe form, which affects 8.5 percent of U.S. adults, periodontitis can impact systemic health.

9 Dec 2012

Nordic project to coordinate initiatives to combat dramatic increase in tick-borne diseases

Last year, more than 40,000 people in Western Scandinavia may have been affected by infections caused by ticks. SEK 17 million has now been invested in a joint Nordic project to coordinate initiatives to combat the dramatic increase in tick-borne diseases.

7 Dec 2012

RedHill Biopharma completes $6.5M private placement

RedHill Biopharma Ltd., an Israeli biopharmaceutical company focusing primarily on development and acquisition of late clinical stage, patent-protected, new formulations and combinations of existing drugs, reported the completion of a private placement in a total amount of approximately $6.5 million.

6 Dec 2012

Study catalogs genetic variation of microbes that live in the gut

Our bodies contain far more microbial genes than human genes. And a new study suggests that just as human DNA varies from person to person, so too does the massive collection of microbial DNA in the intestine.

6 Dec 2012

Johns Hopkins focuses on MRSA, motherhood in November-December 2012 research news brief

Johns Hopkins Nursing researchers focus on MRSA, motherhood, hospital stress, intimate partner violence, and more in the November-December 2012 research news brief.

6 Dec 2012

Breast milk banks: an interview with Dr. Pieter Koorts

The available literature clearly demonstrates that in almost all circumstances a mother’s own breast milk is the ideal food for her infant. This is particularly important for preterm infants. Preterm infants are babies born before 37 completed weeks of pregnancy.

5 Dec 2012

Copper can prevent horizontal transmission of genes in antibiotic-resistant bacteria

New research from the University of Southampton has shown that copper can prevent horizontal transmission of genes, which has contributed to the increasing number of antibiotic-resistant infections worldwide.

5 Dec 2012

Bacteria News and Research

New collaborative model for drug discovery can ensure antibiotics are not lost to resistance

Researchers shed new light on how salmonella bacteria cause infections

Two UT Southwestern researchers to receive 2013 Edith and Peter O'Donnell Award

Clinical trial to examine AstraZeneca experimental drug against pulmonary tuberculosis

Bacteriophages may play an important role in competition among bacterial strains

Top-line results from Durata Therapeutics’ dalbavancin Phase 3 study on ABSSSI

Orientation of antibody binding to bacteria can mean life or death to the bug

Potential way to attack common stomach bacteria that cause ulcers

Communication and checklists may lead to fewer surgical complications

First Edition: December 10, 2012

BlueGenics aims to discover new drugs from deep sea to combat osteoporosis

Researchers track emergence and global spread of healthcare-associated C. difficile

Exposure to passive smoking may increase risk of invasive meningococcal disease in children

C5aRA treatment could be effective against periodontitis

Nordic project to coordinate initiatives to combat dramatic increase in tick-borne diseases

RedHill Biopharma completes $6.5M private placement

Study catalogs genetic variation of microbes that live in the gut

Johns Hopkins focuses on MRSA, motherhood in November-December 2012 research news brief

Breast milk banks: an interview with Dr. Pieter Koorts

Copper can prevent horizontal transmission of genes in antibiotic-resistant bacteria

Microbiology eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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