Bacteria News and Research

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FDA approves Teflaro for treatment of community-acquired bacterial pneumonia

Forest Laboratories, Inc. announced today that Teflaro(ceftaroline fosamil), a broad-spectrum bactericidal cephalosporin with activity against both gram-positive and gram-negative microorganisms, was approved by the U.S. Food and Drug Administration (FDA) for the treatment of community-acquired bacterial pneumonia (CABP), including cases caused by Streptococcus pneumoniae bacteremia, and acute bacterial skin and skin structure infection (ABSSSI), including cases caused by methicillin-resistant Staphylococcus aureus (MRSA).

30 Oct 2010

Research Roundup: Primary care doc pay and satisfaction; fixes to Medicare reimbursements; free vaccines?

A critical element of improving population health in underserved areas is the adequacy and distribution of the primary care physician supply, write the authors of this study, who interviewed 42 primary care physicians from both underserved and non-underserved areas in Los Angeles County, California.

30 Oct 2010

Teflaro receives FDA approval for treatment of bacterial infections

The U.S. Food and Drug Administration today approved Teflaro (ceftaroline fosamil), an injectable antibiotic to treat adults with community acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI), including methicillin-resistant Staphylococcus aureus (MRSA).

30 Oct 2010

New shuttlte program helps probe spaceflight-induced immune-system impairment

When the space shuttle Discovery lifts off on its final flight Nov. 2, its six astronauts will be joined by 16 rodent passengers on a historic mission of their own. Riding in special self-contained modules that automatically supply them with food and water, the mice will be part of a long-term NASA effort aimed at understanding why spaceflight makes humans more vulnerable to infection by viruses and bacteria.

30 Oct 2010

North American children may be 'too clean'

Rising levels of allergic asthma and eczema in North American children have Canadian scientists wondering if there is such a thing as being "too clean." "We see auto-immune diseases like asthma and eczema increasing rapidly in North American children, but we don't see the same effect in children in the developing world," says Dr. B. Brett Finlay, a Professor in the Michael Smith Laboratories at the University of British Columbia.

29 Oct 2010

University of Maryland to establish major research enterprise for autoimmune diseases

With a new $45 million private gift from the family of a grateful patient, the University of Maryland School of Medicine is planning to establish the nation's only major research enterprise devoted to the study of autoimmune and inflammatory diseases such as celiac disease, multiple sclerosis, chronic obstructive pulmonary disease, asthma and Type 1 diabetes. The gift, from Indiana couple Ken and Shelia Cafferty, is the largest private donation in the history of the University System of Maryland.

29 Oct 2010

New nationwide initiative to conduct research on human immune system

A new nationwide research initiative has been launched to define changes in the human immune system's response to infection and vaccination using human rather than animal models, which could lead to better vaccines and other treatments. Baylor Research Institute (BRI), along with five other U.S.-based Human Immune Phenotyping Centers, will receive a total of $100 million over five years to conduct the research.

28 Oct 2010

Disinfection cap dispensing 70% isopropyl alcohol effectively disinfects IV needleless connectors

A study and review performed by clinicians of PICC Excellence, Inc. found a disinfection cap that dispenses 70% isopropyl alcohol is effective in disinfecting IV needleless connectors after five minutes. The study shows that if a needleless connector is covered and bathed in alcohol by the disinfection cap, no drying time is required to kill nearly all pathogens on the connector.

28 Oct 2010

AnaptysBio announces issuance of two new patents for SHM-XEL platform

AnaptysBio, Inc., a privately-held therapeutic antibody platform and product company, announced the issuance of patents in the US and Europe that provide additional coverage for its SHM-XEL platform. These patents extend AnaptysBio's leadership in the use of somatic hypermutation (SHM) for the discovery and optimization of antibodies and other proteins.

28 Oct 2010

Scientists determine tertiary structure of TehA membrane protein in Haemophilus bacteria

Proteins are molecular machines that transport substances, catalyze chemical reactions, pump ions, and identify signaling substances. They are chains of amino acids and the individual amino acid sequence is known for many of them. However, the functions a protein can carry out inside the cell are determined by the three-dimensional spatial structure of the protein. Establishing this so-called tertiary structure presents a great challenge to scientists.

28 Oct 2010

BioSilta releases EnPresso tablet that regulates protein production in recombinant bacteria

BioSilta announces the release of the EnPresso Tablet Cultivation Set, a tabletised form of the patented EnBase technology. The EnBase technology is based on providing an enzymatic-controlled glucose supply in a fed-batch type manner, which allows an extended growth period and promotes higher final cell density.

27 Oct 2010

Expert shares information on detoxification to promote better health

Cold and flu season is right around the corner, so it's time to start taking the steps to keep your body protected. Natural chelation and detoxification expert, Dr. Isaac Eliaz is re-shaping the way we look at detox methods by examining ways to enhance your body's natural defenses and prevent germs from attacking. Dr. Eliaz has profound information on various modalities of detoxification, including effective detox diets, integrative supplement formulas, lifestyle modifications, and detoxification therapies.

27 Oct 2010

USAID announces LAUNCH: Health innovators

The U.S. Agency for International Development (USAID), NASA, NIKE, Inc. and the U.S. Department of State are pleased to announce those selected to participate in the LAUNCH: Health Forum. The innovators selected will participate in an event at NASA's Kennedy Space Center in Florida October 30-31, followed immediately by the launch of the Space Shuttle Discovery on November 1.

27 Oct 2010

Study demonstrates changing levels of nitrite and nitrate in breast milk

Ask someone in the know to list the substances in breast milk that make it the ideal food for newborns and you may hear about proteins that guard against infection, fats that aid in the development of the nervous system and carbohydrates that promote the growth of healthy bacteria. But, you may not hear too much about the nitrite and nitrate in breast milk and their contributions to developing gastrointestinal, immune and cardiovascular systems.

27 Oct 2010

MDI and Westburg enter exclusive distribution agreement for Detect-Ready MRSA panel in Benelux region

Molecular Detection Inc. (MDI), a company developing Detect-Ready™ tests designed to increase the speed and accuracy of infectious disease diagnosis, and life sciences and diagnostics distributor Westburg BV today announced that they have entered into an exclusive agreement for distribution of MDI's Detect-Ready MRSA panel in the Benelux region.

26 Oct 2010

Researchers find new antibiotic strategies for hibernating bugs

New strategies to apply antibiotics more effectively to hibernating bugs have been developed by researchers at the University of Hertfordshire.

26 Oct 2010

Place of birth, low SES and exposure to pests associated with asthma in U.S.-born children

Researchers from Tufts University pooled data from five previous epidemiological studies to investigate the prevalence of asthma in children in the Boston neighborhoods of Chinatown and Dorchester. Among children born in the United States, low socioeconomic status (SES) and exposure to pests (mice and cockroaches) were both associated with having asthma. Neither association was present in children born outside of the United States. The study was published online in advance of print in the Journal of Immigrant and Minority Health.

26 Oct 2010

Study reveals two enzymes help immune cells deploy pathogen-killing traps

A new study reveals that two enzymes help immune cells deploy pathogen-killing traps by unraveling and using the chromatin (DNA and its associated proteins) contained in the cells' nuclei to form defensive webs. The study appears online on October 25 in The Journal of Cell Biology.

26 Oct 2010

Pathogenic listeria tricks intestinal cells to cause sickness

Pathogenic listeria tricks intestinal cells into helping it pass through those cells to make people ill, and, if that doesn't work, the bacteria simply goes around the cells, according to a Purdue University study.

26 Oct 2010

Dietary intake of PUFAs associated with decreased prevalence of periodontitis

Periodontitis, a common inflammatory disease in which gum tissue separates from teeth, leads to accumulation of bacteria and potential bone and tooth loss. Although traditional treatments concentrate on the bacterial infection, more recent strategies target the inflammatory response.

26 Oct 2010