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SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

In a recent study, researchers study the molecular aspects of SARS-CoV-2 host cell entry and inhibition of host-specific cellular mechanisms.

20 Sep 2021

Researcher explores the genetic interplay between personality traits and COVID

In a recent study, scientists aimed to find the genetic effects that the coronavirus disease 2019 (COVID-19) has on individuals with psychiatric disorders.

19 Sep 2021

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

In a recent study, Swiss researchers use improved techniques to understand the biological significance behind the Delta variant.

19 Sep 2021

GIST researchers unravel coordination mechanism of base excision repair

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Guidelines: Summer camp returns to normal during COVID-19

A new report describes measures to ensure that youth activities can continue safely, based on sound epidemiological and infectious disease guidelines.

13 Sep 2021

Study identifies actionable genes and candidate drugs in biliary tract cancer using a knowledgebase

Oncotarget published "Actionability evaluation of biliary tract cancer by genome transcriptome analysis and Asian cancer knowledgebase" which reported that it is necessary to investigate actionable genes and candidate drugs using a sophisticated knowledgebase and characterize BTCs immunologically for evaluating the actionability of molecular and immune therapies.

31 Aug 2021

Headed away to school? Here’s what students with health issues need to know

College is a time of transition, but for those managing chronic medical conditions, it may also be the first time they will be wholly responsible for their own health: setting appointments, securing supplies and pharmaceuticals, and monitoring symptoms.

24 Aug 2021

New study identifies novel compound as promising pan-coronavirus drug candidate

A recent study describes a novel compound with frameshifting capability against MERS-CoV, inhibiting viral propagation within infected cells.

23 Aug 2021

Durable highly protective T cell response to AAV-spike vaccine against COVID-19 pneumonia in mice

New research, available as a preprint on the bioRxiv* server, has focused on the role played by T cell immunity, particularly CD8+ cytotoxic T cells, on preventing lethal infection with SARS-CoV-2 in mice infused with peptide-loaded antigen-presenting dendritic cells (DCs).

19 Aug 2021

A new promising target for broad-spectrum therapeutics against coronaviruses

A recent study by Canadian and US researchers demonstrates how frameshift signals of coronaviruses represent a viable target for developing novel therapeutics with broad-spectrum activity – not only against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also other constituents of the coronavirus family. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

11 Aug 2021

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Last year, University of Alabama at Birmingham researchers reported that reductive stress -; an imbalance in the normal oxidation/reduction homeostasis -; caused pathological changes associated with heart failure in a mouse model.

6 Aug 2021

Next-generation CRISPR tools and therapies improved by modified RNA guides

A new type of gene-editing tool, CRISPR-Cas13, has shown promise in RNA targeting. Previous studies have shown the tool as a potential treatment method for viral diseases, including coronavirus disease (COVID-19).

3 Aug 2021

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

The mutations that give rise to melanoma result from a chemical conversion in DNA fueled by sunlight -; not just a DNA copying error as previously believed, reports a study by Van Andel Institute scientists published today in Science Advances.

30 Jul 2021

Physical pain induces relapse of alcohol consumption, research shows

The study has also shown changes in an area of the brain related to motivation for drug intake, and in a second experiment they have shown that the kappa-type opioid receptor (a protein) is key to causing these animals to relapse.

27 Jul 2021

Brain's "feel good" chemical messenger can be willfully manipulated, study shows

From the thrill of hearing an ice cream truck approaching to the spikes of pleasure while sipping a fine wine, the neurological messenger known as dopamine has been popularly described as the brain's "feel good" chemical related to reward and pleasure.

23 Jul 2021

Bases News and Research

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

Researcher explores the genetic interplay between personality traits and COVID

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

GIST researchers unravel coordination mechanism of base excision repair

Guidelines: Summer camp returns to normal during COVID-19

Study identifies actionable genes and candidate drugs in biliary tract cancer using a knowledgebase

Headed away to school? Here’s what students with health issues need to know

New study identifies novel compound as promising pan-coronavirus drug candidate

Durable highly protective T cell response to AAV-spike vaccine against COVID-19 pneumonia in mice

A new promising target for broad-spectrum therapeutics against coronaviruses

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Next-generation CRISPR tools and therapies improved by modified RNA guides

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

Physical pain induces relapse of alcohol consumption, research shows

Brain's "feel good" chemical messenger can be willfully manipulated, study shows

Vitamin C and TET proteins can work together to give regulatory T cells their life-saving power

A path to treat currently untreatable cases of cystic fibrosis is clearly achievable, study suggests

Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication

Scientists identify existing drugs that may inhibit SARS-CoV-2 virus

Mapping dengue fever hot spots can predict future outbreaks of Zika and chikungunya

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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